Journal of Digestive Cancer Research

Korean Society of Gastrointestinal Cancer Research (대한소화기암연구학회)
권호 표지

Late Occurrence of Multiple Bone Metastasis in Patient with Well Controlled Advanced Pancreatic Cancer

  • Min Cheol Kim (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Da Eun Jeong (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Joon Hyuk Choi (Department of Pathology, Yeungnam University College of Medicine) ;
  • Tae Nyeun Kim (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine)
  • Received : 2016.06.03
  • Accepted : 2016.06.14
  • Published : 2016.06.30
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Abstract

A 67-year-old male was admitted due to abdominal pain. Abdominal CT scan performed in a local clinic showed about 2 cm sized pancreatic tail mass with extensive liver and multiple regional lymph node metastasis. Histology of liver biopsy revealed poorly differentiated adenocarcinoma. He underwent chemotherapy with gemcitabine and erlotinib for 5 cycles followed by 8 cycles of second line chemotherapy with 5-fluorouracil and cisplatin. At 12 months after diagnosis, follow-up abdominal CT scan revealed marked reduction of tumor mass in the liver and pancreas with small residual tumor. After one month of last chemotherapy, he complained radiating pain along left leg. Blood chemistry revealed isolated elevation of alkaline phosphatase (ALP) and multiple bone metastasis were demonstrated in bone scan. Palliative radiation therapy to pelvic bone was performed for the relief of bone pain. The prognosis of advanced pancreatic cancer is extremely poor. We report late occurrence of multiple bone metastasis in a patient with well controlled advanced pancreatic cancer with chemotherapy.

Keywords

References

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