Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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In vitro antibiotic susceptibility of field isolates of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis from Korea

  • Jang, Jisung (Department of Veterinary Medicine, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Kim, Kiju (Department of Veterinary Medicine, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Park, Soyeon (Department of Veterinary Medicine, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Park, Bokyoung (Department of Veterinary Medicine, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Um, Hyungmin (DongBang Co., Ltd.) ;
  • Coulier, Marc (ECO Animal Health) ;
  • Hahn, Tae-Wook (Department of Veterinary Medicine, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • Received : 2016.02.04
  • Accepted : 2016.04.15
  • Published : 2016.06.30
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Abstract

The present study was conducted to determine the antibiotic susceptibilities of local Mycoplasma hyopneumoniae (Mhp) and Mycoplasma hyorhinis (Mhr) filed isolates. Minimum inhibitory concentrations (MICs) of Mhp and Mhr field isolates (twelve each) obtained from enzootic pneumonia-like lung lesions during 2009-2011 from Korea were determined using the broth microdilution method. Tylvalosin showed the highest activity against Mhp and Mhr field isolates, with $MIC_{90}$ values of $0.06{\mu}g/mL$ and $0.12{\mu}g/mL$, respectively. Therefore, Korean Mhp and Mhr isolates are highly susceptible to tylvalosin.

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References

  1. Barate AK, Jang G, Cho SB, Hahn TW. RAPD and SDS-PAGE analysis of Mycoplasma hyorhinis isolates of South Korea. Indian J Anim Sci 2014, 84, 26-28.
  2. Barate AK, Jang GS, Cho S, Hahn TW. Proteomic and genetic diversity of Mycoplasma hyopneumoniae isolates from South Korea. J Pure Appl Microbiol 2013, 7, 3125-3129.
  3. Barate AK, Lee HY, Jeong HW, Truong LQ, Joo HG, Hahn TW. An improved multiplex PCR for diagnosis and differentiation of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis. Korean J Vet Res 2012, 52, 39-43.
  4. Friis NF. Some recommendations concerning primary isolation of Mycoplasma suipneumoniae and Mycoplasma flocculare a survey. Nord Vet Med 1975, 27, 337-339.
  5. Hannan PCT. Guidelines and recommendations for antimicrobial minimum inhibitory concentration (MIC) testing against veterinary mycoplasma species. Vet Res 2000, 31, 373-395. https://doi.org/10.1051/vetres:2000100
  6. Hannan PCT, Windsor GD, de Jong A, Schmeer N, Stegemann M. Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones. Antimicrob Agents Chemother 1997, 41, 2037-2040.
  7. Maes D, Segales J, Meyns T, Sibila M, Pieters M, Haesebrouck F. Control of Mycoplasma hyopneumoniae infections in pigs. Vet Microbiol 2008, 126. 297-309. https://doi.org/10.1016/j.vetmic.2007.09.008
  8. Tavio MM, Poveda C, Assuncao P, Ramirez AS, Poveda JB. In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. Vet Rec 2014, 175, 539. https://doi.org/10.1136/vr.102458
  9. Thongkamkoon P, Narongsak W, Kobayashi H, Pathanasophon P, Kishima M, Yamamoto K. In vitro susceptibility of Mycoplasma hyopneumoniae field isolates and occurrence of fluoroquinolone, macrolides and lincomycin resistance. J Vet Med Sci 2013, 75, 1067-1070. https://doi.org/10.1292/jvms.12-0520
  10. Vicca J, Stakenborg T, Maes D, Butaye P, Peeters J, de Kruif A, Haesebrouck F. In vitro susceptibilities of Mycoplasma hyopneumoniae field isolates. Antimicrob Agents Chemother 2004, 48, 4470-4472. https://doi.org/10.1128/AAC.48.11.4470-4472.2004
  11. Wu CC, Shryock TR, Lin TL, Faderan M, Veenhuizen MF. Antimicrobial susceptibility of Mycoplasma hyorhinis. Vet Microbiol 2000, 76, 25-30. https://doi.org/10.1016/S0378-1135(00)00221-2

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