Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy

정맥 내 지질 유탁액 치료 후 성공적으로 회복한 초오 중독 1례

  • Shin, Hee Jun (Department of Emergency Medicine, College of Medicine, Soon Chun Hyang University Hospital) ;
  • Lim, Hoon (Department of Emergency Medicine, College of Medicine, Soon Chun Hyang University Hospital)
  • 신희준 (순천향대학교 부천병원 응급의학교실) ;
  • 임훈 (순천향대학교 부천병원 응급의학교실)
  • Received : 2016.05.15
  • Accepted : 2016.06.02
  • Published : 2016.06.30
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Abstract

Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.

Keywords

References

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