Biomaterials Research (생체재료학회지)

Korean Society for Biomaterials (한국생체재료학회)
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Research trends in biomimetic medical materials for tissue engineering: commentary

  • Park, Ki Dong (Department of Molecular Science and Technology, Ajou University) ;
  • Wang, Xiumei (School of Materials Science and Engineering, Tsinghua University) ;
  • Lee, Jae Young (School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST)) ;
  • Park, Kyung Min (College of Life Science and Bioengineering, Incheon National University) ;
  • Zhang, ShengMin (Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology) ;
  • Noh, Insup (Convergence Institute of Biomedical Engineering and Biomaterials, Seoul National University of Science and Technology)
  • Received : 2016.01.11
  • Accepted : 2016.02.24
  • Published : 2016.03.01
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Abstract

We introduce our active experts' communications and reviews (Part II) of 2015 Korea-China Joint Symposium on Biomimetic Medical Materials in Republic of Korea, which reflect their perspectives on current research trends of biomimetic medical materials for tissue regeneration in both Korea and China. The communications covered three topics of biomimetics, i.e., 1) hydrogel for therapeutics and extracellular matrix environments, 2) design of electrical polymers for communications between electrical sources and biological systems and 3) design of biomaterials for nerve tissue engineering. The reviews in the Part II will cover biomimetics of 3D bioprinting materials, surface modifications, nano/micro-technology as well as clinical aspects of biomaterials for cartilage.

Keywords

Acknowledgement

Supported by : National Research Foundation of Korea (NRF), Natural Science Foundation of China (NSFC)

References

  1. Lv S, Dudek DM, Cao Y, et al. Designed biomaterials to mimic the mechanical properties of muscles. Nature. 2010;465:69-73. https://doi.org/10.1038/nature09024
  2. He J, Wang XM, Spector M, Cui FZ. Scaffolds for central nervous system tissue engineering. Front Mater Sci. 2012;6:1-25. https://doi.org/10.1007/s11706-012-0157-5
  3. Lutolf MP, Gilbert PM, Blau HM. Designing materials to direct stem-cell fate. Nature. 2009;462:433-41. https://doi.org/10.1038/nature08602
  4. Onoe H, Okitsu T, Itou A, Kato-Negishi M, Gojo R, Kiriya D, et al. Metre-long cell-laden microfibres exhibit tissue morphologies and functions. Nat Mater. 2013;12:584-90. https://doi.org/10.1038/nmat3606
  5. Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell. 2009;5:17-26. https://doi.org/10.1016/j.stem.2009.06.016
  6. Park KM, Gerecht S. Hypoxia-inducible hydrogels. Nat Commun. 2014;5:4075. https://doi.org/10.1038/ncomms5075
  7. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126:677-89. https://doi.org/10.1016/j.cell.2006.06.044
  8. Hurtado A, Cregg JM, Wang HB, Wendell DF, Oudega M, Gilbert RJ, et al. Robust CNS regeneration after complete spinal cord transection using aligned poly-L-lactic acid microfibers. Biomaterials. 2011;32:6068-79. https://doi.org/10.1016/j.biomaterials.2011.05.006
  9. Han S, Wang B, Jin W, Xiao Z, Li X, Ding W, et al. The linear-ordered collagen scaffold-BDNF complex significantly promotes functional recovery after completely transected spinal cord injury in canine. Biomaterials. 2015;41:89-96. https://doi.org/10.1016/j.biomaterials.2014.11.031
  10. Jiang X, Cao HQ, Shi LY, Ng SY, Stanton LW, Chew SY. Nanofiber topography and sustained biochemical signaling enhance human mesenchymal stem cell neural commitment. Acta Biomaterialia. 2012;8:1290-302. https://doi.org/10.1016/j.actbio.2011.11.019
  11. Lim SH, Liu XY, Song H, Yarema KJ, Mao HQ. The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells. Biomaterials. 2010;31:9031-9. https://doi.org/10.1016/j.biomaterials.2010.08.021
  12. Cho YI, Choi JS, Jeong SY, Yoo HS. Nerve growth factor (NGF)-conjugated electrospun nanostructures with topographical cues for neuronal differentiation of mesenchymal stem cells. Acta Biomaterialia. 2010;6:4725-33. https://doi.org/10.1016/j.actbio.2010.06.019
  13. Wallace GG, Higgins MJ, Moulton SE, Wang C. Nanobionics: the impact of nanotechnology on implantable medical bionic devices. Nanoscale. 2012;4:4327-47. https://doi.org/10.1039/c2nr30758h
  14. McCaig CD, Rajnicek AM, Song B, Zhao M. Has electrical growth cone guidance found its potential? Trends Neurosci. 2002;25(7):354-59. https://doi.org/10.1016/S0166-2236(02)02174-4
  15. Patel S, Kurpinski K, Quigley R, Gao H, Hsiao BS, Poo MM, et al. Bioactive nanofibers: synergistic effects of nanotopography and chemical signaling on cell guidance. Nano Lett. 2007;7:2122-28. https://doi.org/10.1021/nl071182z
  16. Pelto J, Bjorninen M, Palli A, Talvitie E, Hyttinen J, Mannerstrom B, et al. Novel polypyrrole-coated polylactide scaffolds enhance adipose stem cell proliferation and early osteogenic differentiation. Tissue Eng Pt A. 2013;19(7-8):882-92. https://doi.org/10.1089/ten.tea.2012.0111
  17. Guimard NK, Gomez N, Schmidt CE. Conducting polymers in biomedical engineering. Prog Polym Sci. 2007;32(8-9):876-921. https://doi.org/10.1016/j.progpolymsci.2007.05.012
  18. Hardy JG, Lee JY, Schmidt CE. Biomimetic conducting polymer-based tissue scaffolds. Curr Opin Biotech. 2013;24:847-54. https://doi.org/10.1016/j.copbio.2013.03.011
  19. Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech. 2011;4:165-78. https://doi.org/10.1242/dmm.004077
  20. Green RA, Lovell NH, Wallace GG, Poole-Warren LA. Conducting polymers for neural interfaces: challenges in developing an effective long-term implant. Biomaterials. 2008;29:3393-99.
  21. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell. 2006;126:677-89. https://doi.org/10.1016/j.cell.2006.06.044
  22. Ding H, Zhong M, Kim YJ, Pholpabu P, Balasubramanian A, Hui CM, et al. Biologically derived soft conducting hydrogels using heparin-doped polymer networks. ACS Nano. 2014;8:4348-57. https://doi.org/10.1021/nn406019m
  23. Shekaran A, Garcia AJ. Nanoscale engineering of extracellular matrixmimetic bioadhesive surfaces and implants for tissue engineering. Biochim Biophys Acta. 2011;1810(3):350-60. https://doi.org/10.1016/j.bbagen.2010.04.006
  24. Gomez N, Lee JY, Nickels JD, Schmidt CE. Micropatterned polypyrrole: a combination of electrical and topographical characteristics for the stimulation of cells. Adv Funct Mater. 2007;17:1645-53. https://doi.org/10.1002/adfm.200600669
  25. Lee JY. Electrically conducting polymer-based nanofibrous scaffolds for tissue engineering applications. Polym Rev. 2013;53:443-59. https://doi.org/10.1080/15583724.2013.806544
  26. Hardy JG, Geissler SA, Aguilar D, Villancio-Wolter MK, Mouser DJ, Sukhavasi RC, et al. Instructive conductive 3D silk foam-based bone tissue scaffolds enable electrical stimulation of stem cells for enhanced osteogenic differentiation. Macromol Biosci. 2015;11:1490-6.
  27. Ma Z, Mao Z, Gao C. Surface modification and property analysis of biomedical polymers used for tissue engineering. Colloid Surf B. 2007;60:137-57. https://doi.org/10.1016/j.colsurfb.2007.06.019
  28. Lee JY, Bashur CA, Milroy CA, Forciniti L, Goldstein AS, Schmidt CE. Nerve growth factor-immobilized electrically conducting fibrous scaffolds for potential use in neural engineering applications. IEEE Trans Nanobiosci. 2012;11(1):15-21. https://doi.org/10.1109/TNB.2011.2159621
  29. Povlich LK, Cho JC, Leach MK, Corey JM, Kim J, Martin DC. Synthesis, copolymerization and peptide-modification of carboxylic acid-functionalized 3,4-ethylenedioxythiophene (EDOTacid) for neural electrode interfaces. Biochim Biophys Acta. 2013;1830(9):4288-93. https://doi.org/10.1016/j.bbagen.2012.10.017
  30. Lee JW, Serna F, Nickels J, Schmidt CE. Carboxylic acid-functionalized conductive polypyrrole as a bioactive platform for cell adhesion. Biomacromolecules. 2006;7(6):1692-5. https://doi.org/10.1021/bm060220q
  31. Kai D, Prabhakaran MP, Jin G, Ramakrishna S. Polypyrrole-contained electrospun conductive nanofibrous membranes for cardiac tissue engineering. J Biomed Mater Res A. 2011;99(3):376-85.
  32. Shi G, Rouabhia M, Wang Z, Dao LH, Zhang Z. A novel electrically conductive and biodegradable composite made of polypyrrole nanoparticles and polylactide. Biomaterials. 2004;25(13):2477-88. https://doi.org/10.1016/j.biomaterials.2003.09.032
  33. Zhu B, Luo SC, Zhao H, Lin HA, Sekine J, Nakao A, et al. Large enhancement in neurite outgrowth on a cell membrane-mimicking conducting polymer. Nat Commun. 2014;5:4523. https://doi.org/10.1038/ncomms5523
  34. Shinde UP, Yeon B, Jeong B. Recent progress of in situ formed gels for biomedical applications. Prog Polym Sci. 2013;38:672-701. https://doi.org/10.1016/j.progpolymsci.2012.08.002
  35. Seliktar D. Designing cell-compatible hydrogels for biomedical applications. Science. 2012;336:1124-8. https://doi.org/10.1126/science.1214804
  36. Park KM, Ko KS, Joung YK, Shin H, Park KD. In situ cross-linkable gelatin-poly (ethylene glycol)-tyramine hydrogel via enzyme-mediated reaction for tissue regenerative medicine. J Mater Chem. 2011;21:13180-7. https://doi.org/10.1039/c1jm12527c
  37. Nguyen MK, Alsberg E. Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine. Prog Polym Sci. 2014;39:1236-65.
  38. Cushing MC, Anseth KS. Hydrogel cell cultures. Science. 2007;316:1133-4. https://doi.org/10.1126/science.1140171
  39. Huebsch N, Mooney DJ. Inspiration and application in the evolution of biomaterials. Nature. 2009;462:426-32. https://doi.org/10.1038/nature08601
  40. Place ES, Evans ND, Stevens MM. Complexity in biomaterials for tissue engineering. Nat Mater. 2009;8:457-70. https://doi.org/10.1038/nmat2441
  41. Highley CB, Rodell CB, Burdick JA. Direct 3D printing of shear‐thinning hydrogels into self‐healing hydrogels. Adv Mater. 2015;27:5075-9. https://doi.org/10.1002/adma.201501234
  42. Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nat Biotech. 2014;32:773-85. https://doi.org/10.1038/nbt.2958

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