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Skin Cancer Concerns in People of Color: Risk Factors and Prevention

  • Gupta, Alpana K (Division of Molecular Cytology, National Institute of Cancer Prevention and Research (Formerly, Institute of Cytology and Preventive Oncology) (ICMR) Department of Health Research) ;
  • Bharadwaj, Mausumi (Division of Molecular Genetics and Biochemistry, National Institute of Cancer Prevention and Research (ICMR)) ;
  • Mehrotra, Ravi (Division of Molecular Cytology, National Institute of Cancer Prevention and Research (Formerly, Institute of Cytology and Preventive Oncology) (ICMR) Department of Health Research)
  • Published : 2016.12.01

Abstract

Background: Though people of color (POC) are less likely to become afflicted with skin cancer, they are much more likely to die from it due to delay in detection or presentation. Very often, skin cancer is diagnosed at a more advanced stage in POC, making treatment difficult.The purpose of this research was to improve awareness regarding skin cancers in people of color by providing recommendations to clinicians and the general public for early detection and photo protection preventive measures. Methods: Data on different types of skin cancers were presented to POC. Due to limited research, there are few resources providing insights for evaluating darkly pigmented lesions in POC. Diagnostic features for different types of skin cancers were recorded and various possible risk factors were considered. Results: This study provided directions for the prevention and early detection of skin cancer in POC based on a comprehensive review of available data. Conclusions: The increased morbidity and mortality rate associated with skin cancer in POC is due to lack of awareness, diagnosis at a more advanced stage and socioeconomic barriers hindering access to care. Raising public health concerns for skin cancer prevention strategies for all people, regardless of ethnic background and socioeconomic status, is the key to timely diagnosis and treatment.

Keywords

References

  1. Agbai ON, Buster K, Sanchez M, et al (2014). Skin cancer and photoprotection in people of color: A review and recommendations for physicians and the public. J Am Acad Dermatol 70,748-62 Available at: http://www.ncbi.nlm.nih. gov/pubmed/24485530 [Accessed September 28, 2016]. https://doi.org/10.1016/j.jaad.2013.11.038
  2. Al-Dujaili Z, Henry M, Dorizas ASS, Sadick NSS (2015). Skin cancer concerns particular to women. Int J Women's Dermatology, 1, 123-25 https://doi.org/10.1016/j.ijwd.2015.07.002
  3. Anand P, Kunnumakkara AB, Sundaram C, et al (2008). Cancer is a preventable disease that requires major lifestyle changes. Pharm Res, 25, 2097-116. https://doi.org/10.1007/s11095-008-9661-9
  4. Anon (n.d.) Cancer Statistics Review, 1975-2013 - SEER Statistics. http://seer.cancer.gov /csr/1975_2013/.
  5. Bigler C, Feldman J, Hall E, Padilla RS (1996). Pigmented basal cell carcinoma in Hispanics. J Am Acad Dermatol, 34,751-52 https://doi.org/10.1016/S0190-9622(96)90007-9
  6. Bradford PT (2009). Skin cancer in skin of color. Dermatol Nurs, 21, 170-77.
  7. Brenner M, Hearing VJ (2008). The protective role of melanin against UV damage in human skin. Photochem Photobiol, 84, 539-49 https://doi.org/10.1111/j.1751-1097.2007.00226.x
  8. Buster KJ, You Z, Fouad M, Elmets C (2012). Skin cancer risk perceptions: a comparison across ethnicity, age, education, gender, and income. J Am Acad Dermatol, 66, 771-79. https://doi.org/10.1016/j.jaad.2011.05.021
  9. Byrd KM, Wilson DC, Hoyler SS, Peck GL (2004) Advanced presentation of melanoma in African Americans. J Am Acad Dermatol, 50, 21-4. https://doi.org/10.1016/S0190-9622(03)02091-7
  10. Chang Y, Barrett JH, Bishop DT, Armstrong BK, et al. (2009). Sun exposure and melanoma risk at different latitudes: A pooled analysis of 5700 cases and 7216 controls. Int J Epidemiol, 38, 814-30. https://doi.org/10.1093/ije/dyp166
  11. Chen YC, Christiani DC, Su HJ, Hsueh YM, Smith TJ RL (2010). Early-life or lifetime sunexposure, sunreaction, andthe risk of squamous cell carcinoma in an Asian population. Cancer Causes Control, 21, 771-76. https://doi.org/10.1007/s10552-010-9505-x
  12. Cheng SY Luk NM, Chong LY (2001). Special features of nonmelanoma skin cancer in Hong Kong Chinese patients: 10-year retrospective study. Int J Women's Dermatology, 7, 22-8.
  13. Cho H, Hall JG, Kosmoski C, Fox RL, Mastin T (2010). Tanning, skin cancer risk, and prevention: a content analysis of eight popular magazines that target female readers, 1997-2006. Health Commun, 25, 1-10. https://doi.org/10.1080/10410230903265938
  14. Cooley JH, Quale LM (2013). Skin cancer preventive behavior and sun protection recommendations. Semin Oncol Nurs, 29, 223-26. https://doi.org/10.1016/j.soncn.2013.06.008
  15. Cress RD, Holly EA (1997). Incidence of cutaneous melanoma among non-Hispanic whites, Hispanics, Asians, and blacks: an analysis of California cancer registry data, 1988-93. Cancer Causes Control, 8, 246-52. https://doi.org/10.1023/A:1018432632528
  16. Cummins DL, Cummins JM, Pantle H, et al (2006). Cutaneous malignant melanoma. Mayo Clin Proc, 81, 500-07. https://doi.org/10.4065/81.4.500
  17. D'Orazio J, Jarrett S, Amaro-Ortiz A, Scott T (2013). UV radiation and the skin. Int J Mol Sci, 14, 12222-48. https://doi.org/10.3390/ijms140612222
  18. Del Bino S, Sok J, Bessac E, Bernerd F (2006). Relationship between skin response to ultraviolet exposure and skin color type. Pigment Cell Res, 19, 606-14. https://doi.org/10.1111/j.1600-0749.2006.00338.x
  19. Donaldson MR, Coldiron BM (2011). No end in sight: the skin cancer epidemic continues. Semin Cutan Med Surg, 30, 3-5. https://doi.org/10.1016/j.sder.2011.01.002
  20. Drucker AM, Rosen CF (2011). Drug-Induced Photosensitivity. Drug Saf, 34, 821-37. https://doi.org/10.2165/11592780-000000000-00000
  21. El_Ghissassi F, Baan R, Straif K, et al (2009). WHO international Agency for research on cancer monograph working group. A review of human carcinogens-part D: radiation. Lancet Oncol, 10, 751-52. https://doi.org/10.1016/S1470-2045(09)70213-X
  22. Finn L, Markovic SN, Joseph RW (2012). Therapy for metastatic melanoma: the past, present, and future. BMC Med, 10, 23-30. https://doi.org/10.1186/1741-7015-10-23
  23. Friedman LC, Bruce S, Weinberg AD, et al (1994). Early detection of skin cancer: racial/ethnic differences in behaviors and attitudes. J Cancer Educ, 9,105-10.
  24. Galiczynski EM, Vidimos AT (2011). Nonsurgical treatment of nonmelanoma skin cancer. Dermatol Clin, 29, 297-09. https://doi.org/10.1016/j.det.2011.01.011
  25. Gloster HM, Neal K (2006). Skin cancer in skin of color. J Am Acad Dermatol, 55, 741-60. https://doi.org/10.1016/j.jaad.2005.08.063
  26. Gohara MA (2008). Skin cancer in skins of color. J Drugs Dermatol, 7, 441-45.
  27. Gordon LG, Scuffham PA, van der Pols JC, et al (2009). Regular sunscreen use is a cost-effective approach to skin cancer prevention in subtropical settings. J Invest Dermatol, 129, 2766-71. https://doi.org/10.1038/jid.2009.141
  28. Gordon R (2013). Skin cancer: An overview of epidemilogy and risk factors. Semin Oncol Nursing, 29, 160-69. https://doi.org/10.1016/j.soncn.2013.06.002
  29. Goss PE, Strasser-Weippl K, Lee-Bychkovsky BL, et al. (2014). Challenges to effective cancer control in China, India, and Russia. Lancet Oncol, 15, 489-38. https://doi.org/10.1016/S1470-2045(14)70029-4
  30. Griffiths CE, Wang TS, Hamilton TA, Voorhees JJ, Ellis CN (1992). A photonumeric scale for the assessment of cutaneous photodamage. Arch Dermatol, 128, 347-51. https://doi.org/10.1001/archderm.1992.01680130061006
  31. Gritz ER, Tripp MK, De Moor CA, et al (2003) Skin cancer prevention counseling and clinical practices of pediatricians. Pediatr Dermatol, 20, 16-24. https://doi.org/10.1046/j.1525-1470.2003.03004.x
  32. Halder RM, Bridgeman-Shah S (1995). Skin cancer in African Americans. Cancer, 75, 667-73. https://doi.org/10.1002/1097-0142(19950115)75:2+<667::AID-CNCR2820751409>3.0.CO;2-I
  33. Halder RM, Ara CJ (2003). Skin cancer and photoaging in ethnic skin. Dermatol Clin, 21, 725-32. https://doi.org/10.1016/S0733-8635(03)00085-8
  34. Hansen L (2014). Skin Cancer , Ref Modul Biomed Res, 10, 1-4.
  35. Hemminki K, Zhang H, Czene K (2003). Time trends and familial risks in squamous cell carcinoma of the skin. Arch Dermatol, 139, 885-89.
  36. Ho SGY, Chan HHL (2009). The Asian dermatologic patient: review of common pigmentary disorders and cutaneous diseases. Am J Clin Dermatol, 10, 153-68. https://doi.org/10.2165/00128071-200910030-00002
  37. Hu S, Parmet Y, Allen G, et al (2009). Disparity in melanoma: a trend analysis of melanoma incidence and stage at diagnosis among whites, Hispanics, and blacks in Florida. Arch Dermatol, 145, 1369-74.
  38. Hughes BR, Wetton N, Collins M, Newton Bishop JA (1996). Health education about sun and skin cancer: language, ideas and perceptions of young children. Br J Dermatol, 134, 624-29. https://doi.org/10.1111/j.1365-2133.1996.tb06960.x
  39. Ichihashi M, Naruse K, Harada S, et al (1995). Trends in nonmelanoma skin cancer in Japan. Recent Results Cancer Res, 139, 263-73.
  40. Imahiyerobo-Ip J, Ip I, Jamal S, Nadiminti U, Sanchez M (2011). Skin cancer awareness in communities of color. J Am Acad Dermatol, 64, 198-200. https://doi.org/10.1016/j.jaad.2010.02.012
  41. Ishihara K, Saida T, Yamamoto A (2001). Japanese skin cancer society prognosis and statistical investigation committee updated statistical data for malignant melanoma in Japan. Int J Clin Oncol, 6, 109-16. https://doi.org/10.1007/PL00012091
  42. Jackson BA (2009). Nonmelanoma skin cancer in persons of color. Semin Cutan Med Surg, 28, 93-5. https://doi.org/10.1016/j.sder.2009.04.010
  43. Jacobsen AA, Galvan A, Lachapelle CC,et al (2016). Defining the need for skin cancer prevention education in uninsured, minority, and immigrant communities. JAMA Dermatol, (in print).
  44. Kaidbey KH, Agin PP, Sayre RM, Kligman AM (1979). Photoprotection by melanin-a comparison of black and Caucasian skin. J Am Acad Dermatol, 1, 249-60. https://doi.org/10.1016/S0190-9622(79)70018-1
  45. Kikuchi A, Shimizu H, Nishikawa T (1996). Clinical histopathological characteristics of basal cell carcinoma in Japanese patients. Arch Dermatol, 132, 320-24 https://doi.org/10.1001/archderm.1996.03890270096014
  46. Kim GK, Del Rosso JQ, Bellew S (2009a). Skin cancer in Asians part 1: Nonmelanoma skin cancer. J Clin Aesthetic Dermatol, 2, 39-42.
  47. Kim M, Boone SL, West DP, et al (2009b). Perception of skin cancer risk by those with ethnic skin. Arch Dermatol, 145, 207-08.
  48. Koh D, Wang H, Lee J, et al (2003). Basal cell carcinoma, squamous cell carcinoma and melanoma of the skin: analysis of the Singapore cancer registry data 1968-97. Br J Dermatol, 148, 1161-66. https://doi.org/10.1046/j.1365-2133.2003.05223.x
  49. Kundu R V, Kamaria M, Ortiz S, et al (2010). Effectiveness of a knowledge-based intervention for melanoma among those with ethnic skin. J Am Acad Dermatol, 62, 777-84. https://doi.org/10.1016/j.jaad.2009.08.047
  50. Lallas A, Apalla Z, Ioannides D, et al (2015). Dermoscopy in the diagnosis and management of basal cell carcinoma. Future Oncol, 11, 2975-84. https://doi.org/10.2217/fon.15.193
  51. Larnier C, Ortonne JP, Venot A, et al (1994). Evaluation of cutaneous photodamage using a photographic scale. Br J Dermatol, 130,167-73. https://doi.org/10.1111/j.1365-2133.1994.tb02895.x
  52. Lazareth V (2013). Management of non-melanoma skin cancer. Semin Oncol Nurs, 29, 182-94. https://doi.org/10.1016/j.soncn.2013.06.004
  53. Lee CS, Lim HW (2003). Cutaneous diseases in Asians. Dermatol Clin, 21, 669-77. https://doi.org/10.1016/S0733-8635(03)00078-0
  54. Leiter U, Eigentler T, Garbe C (2014). Epidemiology of skin cancer. Adv Exp Med Biol, 810, 120-40.
  55. Leiter U, Garbe C (2008) Epidemiology of melanoma and nonmelanoma skin cancer-the role of sunlight. Adv Exp Med Biol, 624, 89-103.
  56. Longstreth J, de Gruijl FR, Kripke ML, et al (1998) Health risks. J Photochem Photobiol B, 46, 20-39. https://doi.org/10.1016/S1011-1344(98)00183-3
  57. Lozano R, Naghavi M, Foreman K, et al. (2012) Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380, 2095-2128. https://doi.org/10.1016/S0140-6736(12)61728-0
  58. Madankumar R, Gumaste PV, Martires K, et al (2016). Acral melanocytic lesions in the United States: Prevalence, awareness, and dermoscopic patterns in skin-of-color and non-Hispanic white patients. J Am Acad Dermatol, 74, 724-30. https://doi.org/10.1016/j.jaad.2015.11.035
  59. Mahon SM (2003). Skin cancer prevention: education and public health issues. Semin Oncol Nurs, 19, 52-61. https://doi.org/10.1053/sonu.2003.50005
  60. Mann D (2016). Moving beyond bob marley: understanding skin cancer in skin of color. Pract Dermatology.
  61. Markovic SN, Erickson LA, Rao RD, et al (2007). Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clin Proc, 82, 364-80. https://doi.org/10.1016/S0025-6196(11)61033-1
  62. Merrill SJ, Subramanian M, Godar DE (2016). Worldwide cutaneous malignant melanoma incidences analyzed by sex, age, and skin type over time (1955-2007): Is HPV infection of androgenic hair follicular melanocytes a risk factor for developing melanoma exclusively in people of Europeanancestry?. Dermatoendocrino, 8, 121539.
  63. Meyer T (2009) Molecular events in skin cancer. Cancer Treat Res, 146, 189-92.
  64. Montagna W, Carlisle K (1991). The architecture of black and white facial skin. J Am Acad Dermatol, 24, 929-37. https://doi.org/10.1016/0190-9622(91)70148-U
  65. Mueller CSL, Reichrath J (2008). Histology of melanoma and nonmelanoma skin cancer. Adv Exp Med Biol, 624, 215-26.
  66. Narayanan DL, Saladi RN, Fox JL (2010). Ultraviolet radiation and skin cancer. Int J Dermatol, 49, 978-86. https://doi.org/10.1111/j.1365-4632.2010.04474.x
  67. Nikolaou V, Stratigos AJ (2014), Emerging trends in the epidemiology of melanoma. Br J Dermatol, 23, 11-19.
  68. Norval M, Lucas RM, Cullen AP, et al (2011). The human health effects of ozone depletion and interactions with climate change. Photochem Photobiol Sci, 10, 199-225. https://doi.org/10.1039/c0pp90044c
  69. Peterlik M, Grant WB, Cross HS (2009) Calcium, vitamin D and cancer. Anticancer Res, 29, 3687-98.
  70. Pipitone M, Robinson JK, Camara C, et al (2002). Skin cancer awareness in suburban employees: a Hispanic perspective. J Am Acad Dermatol, 47, 118-23. https://doi.org/10.1067/mjd.2002.120450
  71. Rigel DS (2010). Epidemiology of melanoma. Semin Cutan Med Surg, 29, 204-9. https://doi.org/10.1016/j.sder.2010.10.005
  72. Riker AI, Zea N, Trinh T (2010). The epidemiology, prevention, and detection of melanoma. Ochsner J, 10, 56-65.
  73. Rubin AI, Chen EH, Ratner D (2005). Basal-cell carcinoma. N Engl J Med, 353, 2262-69. https://doi.org/10.1056/NEJMra044151
  74. Saladi RN, Persaud AN (2005). The causes of skin cancer: a comprehensive review. Drugs Today, 41, 37-53. https://doi.org/10.1358/dot.2005.41.1.875777
  75. Sanchez G, Nova J, Rodriguez-Hernandez AE, et al (2016). Sun protection for preventing basal cell and squamous cell skin cancers. Cochrane database Syst Rev, 7, CD011161.
  76. Simoes MCF, Sousa JJS, Pais AACC (2015). Skin cancer and new treatment perspectives: A review. Cancer Lett, 357, 8-42. https://doi.org/10.1016/j.canlet.2014.11.001
  77. Sng J, Koh D, Siong WC, Choo TB (2009) Skin cancer trends among Asians living in Singapore from 1968 to 2006. J Am Acad Dermatol, 61, 426-32. https://doi.org/10.1016/j.jaad.2009.03.031
  78. Society american cancer (2016) Melanoma Skin Cancer. Cancer Facts & Figs 2016.
  79. Steding-Jessen M, Birch-Johansen F, Jensen A, et al (2010) Socioeconomic status and non-melanoma skin cancer: a nationwide cohort study of incidence and survival in Denmark. Cancer Epidemiol, 34, 689-95. https://doi.org/10.1016/j.canep.2010.06.011
  80. Stern RS (2010). Prevalence of a history of skin cancer in 2007: results of an incidence-based model. Arch Dermatol, 146, 279-82.
  81. Tadokoro T, Kobayashi N, Zmudzka BZ, et al (2003). UVinduced DNA damage and melanin content in human skin differing in racial/ethnic origin. FASEB J, 17, 1177-79. https://doi.org/10.1096/fj.02-0865fje
  82. Togsverd-Bo K, Sorensen SS, Haedersdal M (2013).Organ transplant recipients need intensive control and treatment of skin cancer. Ugeskr Laeger, 175, 1408-11.
  83. Tucker MA, Goldstein AM (2003). Melanoma etiology: where are we?. Oncogene, 22, 3042-52. https://doi.org/10.1038/sj.onc.1206444
  84. Weinstock MA (2006). Cutaneous melanoma: public health approach to early detection. Dermatol Ther, 19, 26-31. https://doi.org/10.1111/j.1529-8019.2005.00053.x
  85. Wu X-C, Eide MJ, King J, et al (2011) Racial and ethnic variations in incidence and survival of cutaneous melanoma in the United States, 1999-2006. J Am Acad Dermatol, 65, 26-37. https://doi.org/10.1016/j.jaad.2010.12.028
  86. Young C (2009). Solar ultraviolet radiation and skin cancer. Occup Med (Lond), 59, 82-88. https://doi.org/10.1093/occmed/kqn170
  87. Zell JA, Cinar P, Mobasher M, et al (2008). Survival for patients with invasive cutaneous melanoma among ethnic groups: the effects of socioeconomic status and treatment. J Clin Oncol, 26, 66-75. https://doi.org/10.1200/JCO.2007.12.3604
  88. Zhu G, Lin J-C, Kim S-B, et al (2016). Asian expert recommendation on management of skin and mucosal effects of radiation, with or without the addition of cetuximab or chemotherapy, in treatment of head and neck squamous cell carcinoma. BMC Cancer, 16, 42-54. https://doi.org/10.1186/s12885-016-2073-z