Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지
DOI QR코드

DOI QR Code

Improved Survival of Cervical Cancer Patients in a Screened Population in Rural India

  • Jayant, Kasturi (Nargis Dutt Memorial Cancer Hospital) ;
  • Sankaranarayanan, Rengaswamy (Early Detection and Prevention Section and Screening Group, World Health Organization -International Agency for Research on Cancer (WHO-IARC)) ;
  • Thorat, Ranjit V (Nargis Dutt Memorial Cancer Hospital) ;
  • Muwonge, Richard (Early Detection and Prevention Section and Screening Group, World Health Organization -International Agency for Research on Cancer (WHO-IARC)) ;
  • Hingmire, Sanjay J (Nargis Dutt Memorial Cancer Hospital) ;
  • Panse, Nandkumar S (Nargis Dutt Memorial Cancer Hospital) ;
  • Shastri, Surendra S (Department of Preventive Oncology, Tata Memorial Center, Tata Memorial Hospital and Cancer Research Institute) ;
  • Malvi, Sylla G (Nargis Dutt Memorial Cancer Hospital) ;
  • Nene, Bhagwan (Nargis Dutt Memorial Cancer Hospital)
  • Published : 2016.11.01
⟨ Previous Next ⟩

Abstract

Objectives: To describe the survival experience of cervix cancer patients in a screened rural population in India. Methods: Included 558 cervical cancer patients diagnosed in 2000-2013 in a cohort of 100,258 women invited for screening during 2000-2003. The primary end point was death from cervical cancer. We used the Kaplan-Meier method to estimate cumulative observed survival and Cox proportional hazards regression to assess the effect of patient characteristics on survival after diagnosis. Results: Of the 558 cases included, 143 (26%) and 114 (20%) were diagnosed in stages IA and IB respectively; 252 (45.2%) were dead, and 306 (54.8%) were alive at the last follow-up. The overall 5-year observed survival was 60.5%. The 5-year survival of stage IA patients was 95.1% and 5.3% for stage IV patients. All surgically treated stage IA patients, 94.1% of stage IB patients receiving intracavitary radiotherapy, 62% of stage IIB, 49% of stage III and 25% of stage IV patients receiving radiotherapy survived for 5 years. Conclusion: Higher 5-year survival in our study than elsewhere in India is due to the high proportion of early stage cancers detected by screening combined with adequate treatment, resulting into a favourable prognosis.

Keywords

References

  1. Bah E, Sam O, Whittle H, et al (2011). Cancer survival in the Gambia, 1993-1997. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 97-106.
  2. Benedet JL, Bender H, Jones H, et al (2000) FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet, 70, 209-62. https://doi.org/10.1016/S0020-7292(00)90001-8
  3. Berrino F, De Angelis R, Sant M, et al (2007). Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995-99: results of the EUROCARE-4 study. Lancet Oncol, 8, 773-83. https://doi.org/10.1016/S1470-2045(07)70245-0
  4. Chen RJ, Lin YH, Chen CA, et al (1999). Influence of histologic type and age on survival rates for invasive cervical carcinoma in Taiwan. Gynecol Oncol, 73, 184-90. https://doi.org/10.1006/gyno.1999.5364
  5. Chokunonga E, Borok MZ, Chirenje ZM, et al (2011). Cancer survival in Harare, Zimbabwe, 1993-1997. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 249-55.
  6. Dikshit R, Kanhere S, Surange S (2011). Cancer survival in Bhopal, India, 1991-1995. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 107-13.
  7. Ferlay J, Soerjomataram I, Ervik M, et al (2013) 'GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet].' International Agency for Research on Cancer: Lyon (Available from: http://globocan.iarc.fr, accessed on 10/04/2016)
  8. Gajalakshmi V, Rajaraman S, Shanta V (2000). A survival study of cervical cancer in Chennai, India. Indian J Cancer, 37, 158-64.
  9. Jayalekshmi P, Gangadharan P, Sebastian P (2011). Cancer survival in Karunagappally, India, 1991-1997. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 125-32.
  10. Jayant K, Nene BM, Dinshaw KA, et al (2011). Cancer survival in Barshi, India, 1993-2000. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 101-6.
  11. Jayant K, Nene BM, Dinshaw KA, et al (1998). Survival from cervical cancer in Barshi registry, rural India. In 'Cancer survival in developing countries', Eds R Sankaranarayanan, RJ Black, and DM Parkin. International Agency for Research on Cancer, Lyon, pp 69-77.
  12. Jayant K, Rao RS, Nene BM, et al (1996). Improved survival in cervical cancer cases in a rural Indian population. Br J Cancer, 74, 285-87. https://doi.org/10.1038/bjc.1996.353
  13. Jensen OM, Parkin DM, Maclennan R, et al (1991) 'Cancer Registration Principles and Methods. IARC Scientific Publications. No.95. International Agency for Research on Cancer: Lyon.
  14. Kosary CL (1994). FIGO stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: an analysis of 1973-87 SEER cases of cancers of the endometrium, cervix, ovary, vulva, and vagina. Semin Surg Oncol, 10, 31-46. https://doi.org/10.1002/ssu.2980100107
  15. Laudico A, Mapua C (2011). Cancer survival in Manila, Philippines, 1994-1995. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon pp 147-54.
  16. Movva S, Noone AM, Banerjee M, et al (2008). Racial differences in cervical cancer survival in the Detroit metropolitan area. Cancer, 112, 1264-71. https://doi.org/10.1002/cncr.23310
  17. Nandakumar A, Anantha N, Venugopal TC (1998). Population-based survival from breast and cervical cancer and lymphoreticular malignancies in Bangalore, India. In 'Cancer survival in developing countries', Eds R Sankaranarayanan, RJ Black, and DM Parkin. International Agency for Research on Cancer, Lyon, pp 61-8.
  18. Ponten J, Adami HO, Bergstrom R, et al (1995). Strategies for global control of cervical cancer. Int J Cancer, 60, 1-26. https://doi.org/10.1002/ijc.2910600102
  19. Ries LAG, Melbert D, Krapcho M, et al (2008) 'Cancer Statistics Review, 1975-2005, National Cancer Institute. Bethesda, MD. Based on November 2007 SEER data submission, posted to the SEER web site. http://seer.cancer.gov/ csr/1975_2005.' National Cancer Institute: Bethesda, MD
  20. Sankaranarayanan R, Nene BM, Shastri SS, et al (2009). HPV screening for cervical cancer in rural India. N Engl J Med, 360, 1385-94. https://doi.org/10.1056/NEJMoa0808516
  21. Sankaranarayanan R, Swaminathan R (2011) 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162.' International Agency for Research on Cancer: Lyon.
  22. Sankaranarayanan R, Swaminathan R, Brenner H, et al (2010). Cancer survival in Africa, Asia, and Central America: a population-based study. Lancet Oncol, 11, 165-73. https://doi.org/10.1016/S1470-2045(09)70335-3
  23. Shanta V, Gajalakshmi CK, Swaminathan R (1998). Cancer survival in Chennai (Madras), India. In 'Cancer survival in developing countries', Eds R Sankaranarayanan, RJ Black, and DM Parkin. International Agency for Research on Cancer, Lyon, pp 89-100.
  24. Sumitsawan Y, Srisukho S, Sastraruji A, et al (2011). Cancer survival in Chiang Mai, Thailand, 1993-1997. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 199-209.
  25. Swaminathan R, Rama R, Nalini S, Shanta V (2011). Cancer survival in Chennai (Madras), India, 1990-1999. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 115-24.
  26. Swaminathan R, Selvakumaran R, Esmy PO, et al (2009). Cancer pattern and survival in a rural district in South India. Cancer Epidemiol, 33, 325-31. https://doi.org/10.1016/j.canep.2009.09.008
  27. Wabinga H, Parkin DM, Nambooze S, Amero J (2011). Cancer survival in Kampala, Uganda, 1993-1997. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 243-7.
  28. Yeole BB, Kumar AV, Kurkure A, et al (2004). Population-based survival from cancers of breast, cervix and ovary in women in Mumbai, India. Asian Pac J Cancer Prev, 5, 308-15.
  29. Yeole BB, Kurkure AP, Sunny L (2011). Cancer survival in Mumbai, India, 1992-1999. In 'Cancer survival in Africa, Asia, the Caribbean and Central America. IARC Scientific Publications volume 162', Eds R Sankaranarayanan and R Swaminathan. International Agency for Research on Cancer, Lyon, pp 133-42.