Asian Pacific Journal of Cancer Prevention

  • 제17권7호
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  • Pages.3243-3248
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  • 2016
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Survival of Patients with Stomach Cancer and its Determinants in Kurdistan

  • Moradi, Ghobad (Department of Epidemiology and Biostatistics, Medical School, Kurdistan University of Medical Sciences) ;
  • Karimi, Kohsar (Department of Epidemiology and Biostatistics, Medical School, Kurdistan University of Medical Sciences) ;
  • Esmailnasab, Nader (Department of Epidemiology and Biostatistics, Medical School, Kurdistan University of Medical Sciences) ;
  • Roshani, Daem (Department of Epidemiology and Biostatistics, Medical School, Kurdistan University of Medical Sciences)
  • 발행 : 2016.07.01
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Stomach cancer is the fourth most common cancer and the second leading cause of death from cancer in the world. In Iran, this type of cancer has high rates of incidence and mortality. This study aimed to assess the survival rate of patients with stomach cancer and its determinants in Kurdistan, a province with one of the highest incidence rates of stomach cancer in the country. Materials and Methods: We studied a total of 202 patients with stomach cancer who were admitted to Tohid Hospital in Sanandaj from 2009 to 2013. Using Kaplan-Meier nonparametric methods the survival rate of patients was calculated in terms of different levels of age at diagnosis, gender, education, residential area, occupation, underweight, and clinical variables including tumor histology, site of tumor, disease stage, and type of treatment. In addition, we compared the survival rates using the log-rank test. Finally, Cox proportional hazards regression was applied using Stata 12 and R 3.1.0 software. The significance level was set at 0.05. Results: The mean age at diagnosis was $64.7{\pm}12.0$ years. The survival rate of patients with stomach cancer was 43.9% and 7% at the first and the fifth year after diagnosis, respectively. The results of log-rank test showed significant relationships between survival and age at diagnosis, education, disease stage, type of treatment, and degree of being underweight (P<0.05). Moreover, according to the results of Cox proportional hazards regression model, the variables of education, disease stage, and type of treatment were associated with patient survival (P<0.05). Conclusions: The survival rate of patients with stomach cancer is low and the prognosis is very poor. Given the poor prognosis of the patients, it is critical to find ways for early diagnosis and facilitating timely access to effective treatment methods.

키워드

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