참고문헌
- Brosnan JT, Jacobs RL, Stead LM, Brosnan ME (2004). Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol, 51, 405-13.
- Brunaud L, Alberto JM, Ayav A, et al (2003). Effects of vitamin B12 and folate deficiencies on DNA methylation and carcinogenesis in rat liver. Clin Chem Lab Med, 41, 1012-9.
- Buemi M, Marino D, Di Pasquale G, et al (2001). Effects of homocysteine on proliferation, necrosis, and apoptosis of vascular smooth muscle cells in culture and influence of folic acid. Thromb Res, 104, 207-13. https://doi.org/10.1016/S0049-3848(01)00363-2
- Carlson MW, Iyer VR, Marcotte EM (2007). Quantitative gene expression assessment identifies appropriate cell line models for individual cervical cancer pathways. BMC Genomics, 8, 117. https://doi.org/10.1186/1471-2164-8-117
- Cheng HY, Gao Y, Lou G (2010). DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer. Eur J Med Res, 15, 20-4. https://doi.org/10.1186/2047-783X-15-1-20
- Choi MS, Shim YH, Hwa JY, et al (2003). Expression of DNA methyltransferases in multistep hepatocarcinogenesis. Hum Pathol, 34, 11-7. https://doi.org/10.1053/hupa.2003.5
- Craciunescu CN, Johnson AR, Zeisel SH (2010). Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr, 140, 1162-6. https://doi.org/10.3945/jn.110.122044
- Crott JW, Liu Z, Keyes MK, et al (2008). Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines. J Nutr Biochem, 19, 328-35. https://doi.org/10.1016/j.jnutbio.2007.05.003
- De Marzo AM, Marchi VL, Yang ES, et al (1999). Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res, 59, 3855-60.
- Delage B, Dashwood RH (2008). Dietary manipulation of histone structure and function. Annu Rev Nutr, 28, 347-66. https://doi.org/10.1146/annurev.nutr.28.061807.155354
- Denis H, Ndlovu MN, Fuks F (2011). Regulation of mammalian DNA methyltransferases: a route to new mechanisms. EMBO Rep, 12, 647-56. https://doi.org/10.1038/embor.2011.110
- Duthie SJ, Narayanan S, Blum S, Pirie L, Brand GM (2000). Folate deficiency in vitro induces uracil misincorporation and DNA hypomethylation and inhibits DNA excision repair in immortalized normal human colon epithelial cells. Nutr Cancer, 37, 245-51. https://doi.org/10.1207/S15327914NC372_18
- Duthie SJ, Narayanan S, Sharp L et al (2004). Folate, DNA stability and colo-rectal neoplasia. Proc Nutr Soc, 63, 571-8. https://doi.org/10.1079/PNS2004
- Etoh T, Kanai Y, Ushijima S, et al (2004). Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am J Pathol, 164, 689-99. https://doi.org/10.1016/S0002-9440(10)63156-2
- Farias N, Ho N, Butler S et al (2015). The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines. J Nutr Biochem, 26, 818-26. https://doi.org/10.1016/j.jnutbio.2015.02.002
- Fatemi M, Hermann A, Gowher H, Jeltsch A (2002). Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA. Eur J Biochem, 269, 4981-4. https://doi.org/10.1046/j.1432-1033.2002.03198.x
- Flatley JE, McNeir K, Balasubramani L, et al (2009). Folate status and aberrant DNA methylation are associated with HPV infection and cervical pathogenesis. Cancer Epidemiol Biomarkers Prev, 18, 2782-9. https://doi.org/10.1158/1055-9965.EPI-09-0493
- Gao Q, Steine EJ, Barrasa MI, et al (2011). Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proc Natl Acad Sci U S A, 108, 18061-6. https://doi.org/10.1073/pnas.1114946108
- GLOBOCAN 2012: Estimated cancer incidence, mortality and prevalence worldwide in 2012. Database: International Agency for Research on Cancer.
- Guo L, Zhu H, Lin C, et al (2015). Associations between antioxidant vitamins and the risk of invasive cervical cancer in Chinese women: A case-control study. Sci Rep, 5, 13607. https://doi.org/10.1038/srep13607
- Habib M, Fares F, Bourgeois CA, et al (1999). DNA global hypomethylation in EBV-transformed interphase nuclei. Exp Cell Res, 249, 46-53. https://doi.org/10.1006/excr.1999.4434
- Hayashi I, Sohn KJ, Stempak JM, Croxford R, Kim YI (2007). Folate deficiency induces cell-specific changes in the steadystate transcript levels of genes involved in folate metabolism and 1-carbon transfer reactions in human colonic epithelial cells. J Nutr, 137, 607-13. https://doi.org/10.1093/jn/137.3.607
- Hlady RA, Novakova S, Opavska J, et al (2012). Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis. J Clin Invest, 122, 163-77. https://doi.org/10.1172/JCI57292
- Hu J, Cheung N-KV (2009). Methionine depletion with recombinant methioninase: in vitro and in vivo efficacy against neuroblastoma and its synergism with chemotherapeutic drugs. Int J Cancer, 124, 1700-6. https://doi.org/10.1002/ijc.24104
- James S, Cross D, Miller B (1992). Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid. Carcinogenesis, 13, 2471-4. https://doi.org/10.1093/carcin/13.12.2471
- James SJ, Pogribny IP, Pogribna M, et al (2003). Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis. J Nutr, 133, 3740-7S. https://doi.org/10.1093/jn/133.11.3740S
- Jones PA, Baylin SB (2007). The epigenomics of cancer. Cell, 128, 683-92. https://doi.org/10.1016/j.cell.2007.01.029
- Jones PL, Veenstra GJ, Wade PA, et al (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet, 19, 187-91. https://doi.org/10.1038/561
- Kim YI, Christman JK, Fleet JC, et al (1995). Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats. Am J Clin Nutr, 61, 1083-90. https://doi.org/10.1093/ajcn/61.5.1083
- Kinney SRM, Pradhan S (2011). Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells. Prog Mol Biol Transl Sci, 101, 311-33.
- Lande-Diner L, Zhang J, Ben-Porath I, et al (2007). Role of DNA methylation in stable gene repression. J Biol Chem, 282, 12194-200. https://doi.org/10.1074/jbc.M607838200
- Liao J, Karnik R, Gu H, et al (2015). Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Nat Genet, 47, 469-78. https://doi.org/10.1038/ng.3258
- Linhart HG, Troen A, Bell GW, et al (2009). Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations. Gastroenterol, 136, 227-35. https://doi.org/10.1053/j.gastro.2008.10.016
- McManus KJ, Biron VL, Heit R, Underhill DA and Hendzel MJ (2006). Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregation. J Biol Chem, 281, 8888-97. https://doi.org/10.1074/jbc.M505323200
- Mizuno S, Chijiwa T, Okamura T, et al (2001). Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood, 97, 1172-9. https://doi.org/10.1182/blood.V97.5.1172
- Nakano E, Taiwo FA, Nugent D, et al (2005). Downstream effects on human low density lipoprotein of homocysteine exported from endothelial cells in an in vitro system. J Lipid Res, 46, 484-93. https://doi.org/10.1194/jlr.M400339-JLR200
- Narayan G, Arias-Pulido H, Koul S, et al (2003). Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: its relationship to clinical outcome. Mol Cancer, 2, 24. https://doi.org/10.1186/1476-4598-2-24
- Niculescu MD, Zeisel SH (2002). Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J Nutr, 132, 2333-5. https://doi.org/10.1093/jn/132.8.2333S
- Ning X, Shi Z, Liu X, et al (2015). DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression. Cancer Lett, 359, 198-205. https://doi.org/10.1016/j.canlet.2015.01.005
- Oh BK, Kim H, Park HJ, et al (2007). DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation. Int J Mol Med, 20, 65-73.
- Pater MM, Pater A (1985). Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix. Virol, 145, 313-8. https://doi.org/10.1016/0042-6822(85)90164-3
- Pogribny IP, Tryndyak VP, Muskhelishvili L, Rusyn I, Ross SA (2007). Methyl deficiency, alterations in global histone modifications, and carcinogenesis. J Nutr, 137, 216-22. https://doi.org/10.1093/jn/137.1.216S
- Rampersaud GC, Kauwell GP, Hutson AD, Cerda JJ, Bailey LB (2000). Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr, 72, 998-1003. https://doi.org/10.1093/ajcn/72.4.998
- Rositch AF, Koshiol J, Hudgens MG, et al (2013). Patterns of persistent genital human papillomavirus infection among women worldwide: a literature review and meta-analysis. Int J Cancer, 133, 1271-85. https://doi.org/10.1002/ijc.27828
- Roura E, Travier N, Waterboer T, et al (2016). The influence of hormonal factors on the risk of developing cervical cancer and pre-cancer: results from the EPIC cohort. PLoS One, 11, 147029.
- Sawada M, Kanai Y, Arai E, et al (2007). Increased expression of DNA methyltransferase 1 (DNMT1) protein in uterine cervix squamous cell carcinoma and its precursor lesion. Cancer Lett, 251, 211-9. https://doi.org/10.1016/j.canlet.2006.11.023
- Stead LM, Au KP, Jacobs RL, Brosnan ME, Brosnan JT (2001). Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate. Am J Physiol Endocrinol Metab, 281, 1095-100. https://doi.org/10.1152/ajpendo.2001.281.5.E1095
- Stempak JM, Sohn KJ, Chiang E-P, Shane B, Kim YI (2005). Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model. Carcinogenesis, 26, 981-90. https://doi.org/10.1093/carcin/bgi037
- Su PH, Lin YW, Huang RL, et al (2013). Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer. Oncogene, 32, 15-26. https://doi.org/10.1038/onc.2012.29
- Sun J, Ji J, Huo G, Song Q, Zhang X (2015). miR-182 induces cervical cancer cell apoptosis through inhibiting the expression of DNMT3a. Int J Clin Exp Pathol, 8, 4755-63.
- Wang SM, Colombara D, Shi JF, et al. (2013). Six-year regression and progression of cervical lesions of different human papillomavirus viral loads in varied histological diagnoses. Int J Gynecol Cancer, 23, 716-23. https://doi.org/10.1097/IGC.0b013e318286a95d
- Wasson GR, McGlynn AP, McNulty H, et al (2006). Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation. J Nutr, 136, 2748-53. https://doi.org/10.1093/jn/136.11.2748
- Woo HJ, Kim SJ, Song KJ, et al (2015). Hypermethylation of the tumor-suppressor cell adhesion molecule 1 in human papillomavirus-transformed cervical carcinoma cells. Int J Oncol, 46, 2656-62. https://doi.org/10.3892/ijo.2015.2945
- Wu Y, Meng L, Wang H, et al (2006). Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis. Oncol Rep, 16, 625-9.
- Ziegler RG, Weinstein SJ, Fears TR, (2002). Nutritional and genetic inefficiencies in one-carbon metabolism and cervical cancer risk. J Nutr, 132, 2345-9. https://doi.org/10.1093/jn/132.8.2345S
- Zhang Y, Chen FQ, Sun YH, et al (2011). Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells. J Exp Clin Cancer Res, 30, 98. https://doi.org/10.1186/1756-9966-30-98