Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Opisthorchis viverrini Infection Among People in the Border Areas of Three Provinces, Northeast of Thailand

  • Published : 2016.06.01
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Abstract

Opisthorchis viverrini is still a serious problem in Northeastern and Northern Thailand. Active surveillance is required to determine updated data for further prevention and control planning. Therefore, this study aimed to examine the prevalence and risk factors for O. viverrini in three provinces, Northeastern Thailand. A cross-sectional survey was conducted during October 2015 to March 2016 at Kaeng Sanam Nang district of Nakhon Ratchasima province, Waeng Noi district of Khon Kaen province, and Khon Sawan district of Chaiyaphum province, Thailand. Stool samples were examined by using a modified Kato-Katz Thick smear technique. From a total of 978 participants screened, O. viverrini infection was found in 1.74%, the majority opf positive cases being male (6.62%), age group 51-60 years old (4.21%), educated at primary school (8.43%), occupied with agriculture (9.62%),having an income <4,000 baht per month (4.82%), and living in Khon Sawan district (8.43%). Participants had a high knowledge level (42.43%), good attitude level (34.76%), and fair level (38.04%). The present study indicates the O. viverrini infection rate is low, but elderly males with primary school education involved in agriculture are still frequently effected particularly in Khon Sawan district. Therefore, this risk group requires behavior modification and continued monitoring.

Keywords

Acknowledgement

Supported by : Suranaree University of Technology (SUT)

References

  1. Best JW (1977). Research in Education (3rd ed). Englewood Cliffs, NJ: Prentice-Hall.
  2. Andrews RH, Sithithaworn P, Petney TN (2008). Opisthorchis viverrini: an Underestimated Parasite in World Health. Trends Parasitol, 24, 497-501. https://doi.org/10.1016/j.pt.2008.08.011
  3. Bloom BS (1971). Handbook on Formative and Summative of Student Learning. New York: Mc Graw-Hill Book Company.
  4. Grundy-Warr C, Andrews RH, Sithithaworn P, et al (2012). Raw attitudes, wetland cultures, life-cycles: Socio-cultural dynamics relating to Opisthorchis viverrini in the Mekong Basin. Parasitol Int, 61, 65-70. https://doi.org/10.1016/j.parint.2011.06.015
  5. Harinasuta C, Vajrasthira S (1960). Opisthorchiasis in Thailand. Am J Trop Med Hyg, 54, 100-5.
  6. Harinasuta T, Riganti M, Bunnag D (1984). Opisthorchis viverrini infection: pathogenesis and clinical features. Arzneimittelforschung, 34, 1167-9.
  7. IARC (1994). Infection with Liver Flukes (Opisthorchis viverrini, opisthorchis felineus and clonrochis sinensis). IARC Monogr Eval Carcinog Risks of Hum, 61, 121-75.
  8. Jongsuksuntigul P, Imsomboon T (2003). Opisthorchiasis Control in Thailand. Acta Trop, 88, 229-32. https://doi.org/10.1016/j.actatropica.2003.01.002
  9. Kaewpitoon SJ, Kaewpitoon N, Rujirakul R, et al (2015). The Carcinogenic Liver Fluke Opisthorchis viverrini among Rural community people in northeast thailand: a crosssectional descriptive study using multistage sampling technique. Asian Pac J Cancer Prev, 16, 7803-7. https://doi.org/10.7314/APJCP.2015.16.17.7803
  10. Kaewpitoon SJ, Rujirakul R, Loyd RA, et al (2016). Re-Examination of Opisthorchis viverrini in nakhon ratchasima province, northeastern thailand, indicates continued needs for health intervention. Asian Pac J Cancer Prev, 17, 231-4.
  11. Kaewpitoon SJ, Rujirakul R, Ueng-Arporn N, et al (2012). Community-based cross-sectional study of carcinogenic human liver fluke in elderly from surin province, Thailand. Asian Pac J Cancer Prev, 13, 4285-8. https://doi.org/10.7314/APJCP.2012.13.9.4285
  12. Kaewpitoon N, Kootanavanichpong N, Kompor P, et al (2015). Review and current status of opisthorchis viverrini infection at the community level in Thailand. Asian Pac J Cancer Prev, 16, 6825-30 https://doi.org/10.7314/APJCP.2015.16.16.6825
  13. Krejcie RV, Morgan EW (1970). Determining Sample Size for Research Activities. J Edu Psychol Measure, 10, 308.
  14. Likert R (1932). A Technique for the Measurement of Attitudes, Arc Psychol, 140, 44, 53.
  15. Parkin DM (2006). The global health burden of infectionassociated cancers in the Year 2002. Int J Cancer, 118, 3030-44. https://doi.org/10.1002/ijc.21731
  16. Parkin DM, Ohshima H, Srivatanakul P, et al (1993). Cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention. Cancer Epidemiol Biomarkers Prev, 2, 537-44.
  17. Shin H-R, Oh J-K, Masuyer E, et al (2010). Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci, 101, 579-85. https://doi.org/10.1111/j.1349-7006.2009.01458.x
  18. Sithithaworn P, Andrews RH, Nguyen VD, et al (2012). The Current Status of Opisthorchiasis and Clonorchiasis in the Mekong Basin. Parasitol International, 61, 10-6. https://doi.org/10.1016/j.parint.2011.08.014
  19. Sithithaworn P, Pipitgool V, Srisawangwong T, et al (1997. Seasonal variation of Opisthorchis viverrini infection in cyprinoid fish in north-east Thailand: implications for parasite control and food safety. Bull World Health Organ, 75, 125-31.
  20. Sripa B, Brindley PJ, Mulvenna J, et al (2012). The tumorigenic liver fluke Opisthorchis viverrini-multiple pathways to cancer. Trends Parasitol, 28, 395-407. https://doi.org/10.1016/j.pt.2012.07.006
  21. Sripa B, Kaewkes S, Intapan PM, et al (2010). Food-borne trematodiases in southeast asia: epidemiology, pathology, clinical manifestation and control. Adv Parasitol, 72, 305-50.
  22. Sripa B, Kaewkes S, Sithithaworn P, et al (2007). Liver Fluke Induces Cholangiocarcinoma. PLoS Med, 4, 201. https://doi.org/10.1371/journal.pmed.0040201
  23. Sripa B, Pairojkul C 2008. Cholangiocarcinoma: Lessons From Thailand. Curr Opin Gastroenterol, 24, 349-56. https://doi.org/10.1097/MOG.0b013e3282fbf9b3
  24. Suwannahitatorn P, Klomjit S, Naaglor T, et al (2013). A Follow-Up Study of Opisthorchis viverrini infection after the implementation of control program in a rural community, central Thailand. Parasit Vectors, 6, 188. https://doi.org/10.1186/1756-3305-6-188
  25. Thamavit W, Bhamarapravati N, Sahaphong S, et al (1978). Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-ifected syrian golden hamsters. Cancer Res, 38, 4634-9.
  26. World Health Organization. Geneva: World Health Organization (1991). Basic laboratory methods in medical parasitology. 25-28.
  27. Wongsaroj T, Nithikathkul C, Rojkitikul W, et al (2014). National survey of helminthiasis in Thailand. Asian Biomedicine, 8, 779-83. https://doi.org/10.5372/1905-7415.0806.357