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Mutations in PIK3CA Sensitize Breast Cancer Cells to Physiologic Levels of Aspirin

  • Dirican, Ebubekir (Marmara University, School of Medicine Department of Medical Biology)
  • 발행 : 2016.05.01

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참고문헌

  1. Dirican E, Akkiprik M, Ozer A (2016). Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer. Tumour Biol. [Epub ahead of print]
  2. Dirican E, Kaya Z, Gullu G, et al (2014). Detection of PIK3CA gene mutations with HRM analysis and association with IGFBP-5 expression levels in breast cancer. Asian Pac J Cancer Prev, 15, 9327-33. https://doi.org/10.7314/APJCP.2014.15.21.9327
  3. Gallia GL, Rand V, Siu IM, et al (2006) PIK3CA gene mutations in pediatric and adult glioblastoma multiforme. Mol Cancer Res, 4, 709-14 https://doi.org/10.1158/1541-7786.MCR-06-0172
  4. Juarez Olguin H, Flores Perez J, Lares Asseff I, Loredo Abdala A, Carbajal Rodriguez L (2004). Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases. Biopharm Drug Dispos, 25, 1-7. https://doi.org/10.1002/bdd.379
  5. Klarenbeek S, van Miltenburg MH, Jonkers J (2013). Genetically engineered mouse models of PI3K signaling in breast cancer. Mol Oncol, 7, 146-64 https://doi.org/10.1016/j.molonc.2013.02.003
  6. Turturro SB, Najor MS, Ruby CE, Cobleigh MA, Abukhdeir AM (2016). Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin. Breast Cancer Res Treat, 156, 33-43. https://doi.org/10.1007/s10549-016-3729-8
  7. Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM (1985). Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature, 315, 239-42 https://doi.org/10.1038/315239a0