Restorative Dentistry and Endodontics

The Korean Academy of Conservative Dentistry (대한치과보존학회)
권호 표지
DOI QR코드

DOI QR Code

The effect of different fluoride application methods on the remineralization of initial carious lesions

  • Byeon, Seon Mi (Department of Dental Biomaterials and Institute of Biodegradable Material, Institute of Oral Bioscience and BK21 plus project, School of Dentistry, Chonbuk National University) ;
  • Lee, Min Ho (Department of Dental Biomaterials and Institute of Biodegradable Material, Institute of Oral Bioscience and BK21 plus project, School of Dentistry, Chonbuk National University) ;
  • Bae, Tae Sung (Department of Dental Biomaterials and Institute of Biodegradable Material, Institute of Oral Bioscience and BK21 plus project, School of Dentistry, Chonbuk National University)
  • Received : 2015.11.10
  • Accepted : 2016.04.14
  • Published : 2016.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to assess the effect of single and combined applications of fluoride on the amount of fluoride release, and the remineralization and physical properties of enamel. Materials and Methods: Each of four fluoride varnish and gel products (Fluor Protector, FP, Ivoclar Vivadent; Tooth Mousse Plus, TM, GC; 60 Second Gel, A, Germiphene; CavityShield, CS, 3M ESPE) and two fluoride solutions (2% sodium fluoride, N; 8% tin(ii) fluoride, S) were applied on bovine teeth using single and combined methods (10 per group), and then the amount of fluoride release was measured for 4 wk. The electron probe microanalysis and the Vickers microhardness measurements were conducted to assess the effect of fluoride application on the surface properties of bovine teeth. Results: The amount of fluoride release was higher in combined applications than in single application (p < 0.05). Microhardness values were higher after combined applications of N with FP, TM, and CS than single application of them, and these values were also higher after combined applications of S than single application of A (p < 0.05). Ca and P values were higher in combined applications of N with TM and CS than single application of them (p < 0.05). They were also increased after combined applications of the S with A than after single application (p < 0.05). Conclusions: Combined applications of fluoride could be used as a basis to design more effective methods of fluoride application to provide enhanced remineralization.

Keywords

References

  1. Muhlemann HR, Rudolf ER. Fluoride retention after rinsing with sodium fluoride and amine fluoride. Helv Odontol Acta 1975;19:81-84.
  2. Galagan DJ, Knutson JW. The effect of topically applied fluorides on dental caries experience; report of findings with two, four and six applications of sodium fluoride and of lead fluoride. Public Health Rep 1947;62:1477-1483. https://doi.org/10.2307/4586302
  3. Knutson JW, Armstrong WD. The effect of topically applied sodium fluoride on dental caries experience. Public Health Rep 1943;58:1701-1715. https://doi.org/10.2307/4584683
  4. Cury JA, Tenuta LM. How to maintain a cariostatic fluoride concentration in the oral environment. Adv Dent Res 2008;20:13-16. https://doi.org/10.1177/154407370802000104
  5. Tenuta LM, Cury JA. Fluoride: its role in dentistry. Braz Oral Res 2010;24:9-17. https://doi.org/10.1590/S1806-83242010000500003
  6. Lata S, Varghese NO, Varughese JM. Remineralization potential of fluoride and amorphous calcium phosphatecasein phospho peptide on enamel lesions: an in vitro comparative evaluation. J Conserv Dent 2010;13:42-46. https://doi.org/10.4103/0972-0707.62634
  7. Lee YE, Baek HJ, Choi YH, Jeong SH, Park YD, Song KB. Comparison of remineralization effect of three topical fluoride regimens on enamel initial carious lesions. J Dent 2010;38:166-171. https://doi.org/10.1016/j.jdent.2009.10.002
  8. ten Cate JM, Jongebloed WL, Arenas J. Remineralization of artificial enamel lesions in vitro. IV. Influence of fluorides and diphosphonates on short- and long-term reimineralization. Caries Res 1981;15:60-69. https://doi.org/10.1159/000260501
  9. American Dental Association Council on Scientific Affairs. Professionally applied topical fluoride: evidence-based clinical recommendations. J Dent Educ 2007;71:393-402.
  10. Ostela I, Karhuvaara L, Tenovuo J. Comparative antibacterial effects of chlorhexidine and stannous fluoride-amine fluoride containing dental gels against salivary mutans streptococci. Scand J Dent Res 1991;99:378-383.
  11. Ellingsen JE, Rolla G. Treatment of dentin with stannous fluoride-SEM and electron microprobe study. Scand J Dent Res 1987;95:281-286.
  12. Paraskevas S, Van der Weijden GA. A review of the effects of stannous fluoride on gingivitis. J Clin Periodontol 2006;33:1-13.
  13. Liu X, Zhou X, Guo B, Jin S, Zhang P. Observation on the inhibiting effect of fluor protector on the demineralization of bovine enamel after exposure to some beverages. Hua Xi Yi Ke Da Xue Xue Bao 2002;33:250-252.
  14. Al Zraikat H, Palamara JE, Messer HH, Burrow MF, Reynolds EC. The incorporation of casein phosphopeptide-amorphous calcium phosphate into a glass ionomer cement. Dent Mater 2011;27:235-243. https://doi.org/10.1016/j.dental.2010.10.008
  15. Shen C, Autio-Gold J. Assessing fluoride concentration uniformity and fluoride release from three varnishes. J Am Dent Assoc 2002;133:176-182. https://doi.org/10.14219/jada.archive.2002.0141
  16. Seppa L. Fluoride varnishes in caries prevention. Med Princ Pract 2004;13:307-311. https://doi.org/10.1159/000080466
  17. Cho MJ, Lee HL. A study on the effect of multiapplication of fluoride on enamel remineralization. J Korean Soc Hyg Educ 2001;1:125-132.
  18. Pai N, McIntyre J, Tadic N, Laparidis C. Comparative uptake of fluoride ion into enamel from various topical fluorides in vitro. Aust Dent J 2007;52:41-46. https://doi.org/10.1111/j.1834-7819.2007.tb00464.x
  19. Crall JJ, Bjerga JM. Fluoride uptake and retention following combined applications of APF and stannous fluoride in vitro. Pediatr Dent 1984;6:226-229.
  20. Lee MS, Park DY, Ma DS. The remineralization effect of topical fluoride agents on artificial enamel caries. J Korean Acad Oral Health 2012;36:85-90.
  21. Ngo H, Ruben J, Arends J, White D, Mount GJ, Peters MC, Faller RV, Pfarrer A. Electron probe microanalysis and transverse microradiography studies of artificial lesions in enamel and dentin: a comparative study. Adv Dent Res 1997;11:426-432. https://doi.org/10.1177/08959374970110040801
  22. Kodaka T, Debari K, Yamada M, Kuroiwa M. Correlation between microhardness and mineral content in sound human enamel. Caries Res 1992;26:139-141. https://doi.org/10.1159/000261498
  23. Feagin F, Koulourides T, Pigman W. The characterization of enamel surface demineralization, remineralization, and associated hardness changes in human and bovine material. Arch Oral Biol 1969;14:1407-1417. https://doi.org/10.1016/0003-9969(69)90258-1
  24. Feagin F, Patel PR, Koulourides T, Pigman W. Study of the effect of calcium, phosphate, fluoride and hydrogen ion concentrations on the remineralization of partially demineralized human and bovine enamel surfaces. Arch Oral Biol 1971;16:535-548. https://doi.org/10.1016/0003-9969(71)90199-3
  25. Reynolds EC, Cai F, Cochrane NJ, Shen P, Walker GD, Morgan MV, Reynolds C. Fluoride and casein phosphopeptide-amorphous calcium phosphate. J Dent Res 2008;87:344-348. https://doi.org/10.1177/154405910808700420
  26. ten Cate JM, Featherstone JD. Mechanistic aspects of the interactions between fluoride and dental enamel. Crit Rev Oral Biol Med 1991;2:283-296. https://doi.org/10.1177/10454411910020030101
  27. Lee YJ, Kwon TY, Kim YK. In Vitro effectiveness of remineralizing treatments for protecting early carious lesions from further acid dissolution. Korean J Dent Mater 2013;40:41-50.
  28. Crall JJ, Silverstone LM, Clarkson BH, Wefel JS, Wei SH. Fluoride uptake and in vitro caries-like lesion formation in enamel after two-step topical fluoride applications. Caries Res 1982;16:162-169. https://doi.org/10.1159/000260593

Cited by

  1. Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis vol.51, pp.5, 2017, https://doi.org/10.1159/000478668
  2. Intérêt prophylactique et thérapeutique des chewing-gums sans sucre en orthodontie. Une étude menée auprès de professionnels de santé et de patients vol.88, pp.3, 2017, https://doi.org/10.1051/orthodfr/2017020
  3. Effects of nicomethanol hydrofluoride on dental enamel and synthetic apatites: a role for anti-caries protection pp.1996-9805, 2017, https://doi.org/10.1007/s40368-017-0314-8
  4. Bleaching of simulated stained-remineralized caries lesions in vitro pp.1436-3771, 2018, https://doi.org/10.1007/s00784-018-2590-z
  5. Short-Time Antibacterial Effects of Dimethylaminododecyl Methacrylate on Oral Multispecies Biofilm In Vitro vol.2019, pp.2314-6141, 2019, https://doi.org/10.1155/2019/6393470
  6. Clinical and laboratory evaluation of the Elgydium Protection caries toothpaste effectiveness in patients with high intensity of dental caries vol.98, pp.3, 2019, https://doi.org/10.17116/stomat20199803121
  7. Release and Recharge of Fluoride Ions from Acrylic Resin Modified with Bioactive Glass vol.13, pp.7, 2016, https://doi.org/10.3390/polym13071054