DOI QR코드

DOI QR Code

Prevalence of Trichomoniasis by PCR in Women Attending Health Screening in Korea

  • Kim, Seung-Ryong (Department of Obstetrics and Gynecology, Hanyang University Guri Hospital, College of Medicine) ;
  • Kim, Jung-Hyun (Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine) ;
  • Gu, Na-Yeong (Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine) ;
  • Kim, Yong-Suk (Department of Biochemistry and Molecular Biology, Hanyang University College of Medicine) ;
  • Hong, Yeon-Chul (Department of Parasitology, School of Medicine, Kyungpook National University) ;
  • Ryu, Jae-Sook (Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine)
  • 투고 : 2016.02.24
  • 심사 : 2016.04.05
  • 발행 : 2016.04.30

초록

Trichomoniasis is the most common curable sexually-transmitted infection (STI) worldwide. There are few reports on the prevalence of Trichomonas vaginalis in Korea. The purpose of this study was to examine the prevalence of trichomoniasis by PCR in Guri city, Korea. All adult women who visited Hanyang University Guri Hospital for health screening within the National Health Care Service were invited to participate in the study, and 424 women were enrolled between March and June 2011. PCR was used to detect Trichomonas vaginalis using primers based on a repetitive sequence cloned from T. vaginalis (TV-E650). Fourteen women (3.3%) were found to have T. vaginalis. All were over 50, and they were significantly older on average than the 410 Trichomonas-negative women (mean ages 63.4 vs 55.3 years). It seems that T. vaginalis infection is not rare in women receiving health screening, especially among those over 50.

키워드

참고문헌

  1. World Health Organization. Prevalence and incidence of selected sexually transmitted infections, Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, and Trichomonas vaginalis: methods and results used by the WHO to generate 2005 estimates. Geneva, Switzerland. WHO, 2011.
  2. Secor WE, Meites E, Starr MC, Workowski KA. Neglected parasitic infections in the United States: trichomoniasis. Am J Trop Med Hyg 2014; 90: 800-804. https://doi.org/10.4269/ajtmh.13-0723
  3. Sena AC, Miller WC, Hobbs MM, Schwebke JR, Leone PA, Swygard H, Atashili J, Cohen MS. Trichomonas vaginalis infection in male sexual partners: implications for diagnosis, treatment, and prevention. Clin Infect Dis 2007; 44: 13-22. https://doi.org/10.1086/511144
  4. Kim SJ, Lee DS, Lee SJ. The prevalence and clinical significance of urethritis and cervicitis in asymptomatic people by use of multiplex polymerase chain reaction. Korean J Urol 2011; 52: 703-708. https://doi.org/10.4111/kju.2011.52.10.703
  5. Lee SJ, Park DC, Lee DS, Choe HS, Cho YH. Evaluation of $Seeplex^{(R)}$ STD6 ACE detection kit for the diagnosis of six bacterial sexually transmitted infections. J Infect Chemother 2012; 18: 494-500. https://doi.org/10.1007/s10156-011-0362-7
  6. Goo YK, Shin WS, Yang HW, Joo SY, Song SM, Ryu JS, Lee WM, Kong HH, Lee WK, Lee SE, Lee WJ, Chung DI, Hong Y. Prevalence of Trichomonas vaginalis in women visiting 2 obstetrics and gynecology clinics in Daegu, South Korea. Korean J Parasitol 2016; 54: 75-80. https://doi.org/10.3347/kjp.2016.54.1.75
  7. Kim SR, Kim JH, Park SJ, Lee HY, Kim YS, Kim YM, Hong YC, Ryu JS. Comparison between mixed lysate antigen and ${\alpha}$-actinin antigen in ELISA for serodiagnosis of trichomoniasis. Parasitol Int 2015; 64: 405-407. https://doi.org/10.1016/j.parint.2015.06.003
  8. Ryu JS, Chung HL, Min DY, Cho YH, Ro YS, Kim SR. Diagnosis of trichomoniasis by polymerase chain reaction. Yonsei Med J 1999; 40: 56-60. https://doi.org/10.3349/ymj.1999.40.1.56
  9. Moon HS, Lee TY, Hwang HS, Ahn MH, Ryu JS. PCR for diagnosis of male Trichomonas vaginalis infection with chronic prostatitis and urethritis. Korean J Parasitol 2012; 50: 157-159. https://doi.org/10.3347/kjp.2012.50.2.157
  10. Paces J, Urbankova V, Urbanek P. Cloning and characterization of a repetitive DNA sequence specific for Trichomonas vaginalis. Mol Biochem Parasitol 1992; 54: 247-255. https://doi.org/10.1016/0166-6851(92)90116-2
  11. Bowden FJ, Paterson BA, Mein J, Savage J, Fairley CK, Garland SM, Tabrizi SN. Estimating the prevalence of Trichomonas vaginalis, Chlamydia trachomatis, Neisseria gonorrhoeae, and human papillomavirus infection in indigenous women in northern Australia. Sex Transm Infect 1999; 75: 431-434. https://doi.org/10.1136/sti.75.6.431
  12. Zigas V. An evaluation of trichomoniasis in two ethnic groups in Papua New Guinea. Sex Transm Dis 1977; 4: 63-65. https://doi.org/10.1097/00007435-197704000-00008
  13. Burch TA, Rees CW, Reardon LV. Epidemiological studies on human trichomoniasis. Am J Trop Med Hyg 1959; 8: 312-318. https://doi.org/10.4269/ajtmh.1959.8.312
  14. Murta EF, Silva AO, Silva EA, Adad SJ. Frequency of infectious agents for vaginitis in non- and hysterectomized women. Arch Gynecol Obstet 2005; 273: 152-156. https://doi.org/10.1007/s00404-005-0023-0
  15. Phukan N, Parsamand T, Brooks AE, Nguyen TN, Simoes-Barbosa A. The adherence of Trichomonas vaginalis to host ectocervical cells is influenced by lactobacilli. Sex Transm Infect 2013; 89: 455-459. https://doi.org/10.1136/sextrans-2013-051039
  16. Lang WR. Vaginal acidity and pH; a review. Obstet Gynecol Surv 1955; 10: 546-560. https://doi.org/10.1097/00006254-195508000-00009
  17. Redondo-Lopez V, Cook RL, Sobel JD. Emerging role of lactobacilli in the control and maintenance of the vaginal bacterial microflora. Rev Infect Dis 1990; 12: 856-872. https://doi.org/10.1093/clinids/12.5.856

피인용 문헌

  1. Status of common parasitic diseases in Korea in 2019 vol.62, pp.8, 2016, https://doi.org/10.5124/jkma.2019.62.8.437