The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?

  • Yew, Wing Wai (Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong) ;
  • Koh, Won-Jung (Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2015.05.06
  • Accepted : 2015.05.11
  • Published : 2016.01.01
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Abstract

A worsening scenario of drug-resistant tuberculosis has increased the need for new treatment strategies to tackle this worldwide emergency. There is a pressing need to simplify and shorten the current 6-month treatment regimen for drug-susceptible tuberculosis. Rifamycins and fluoroquinolones, as well as several new drugs, are potential candidates under evaluation. At the same time, treatment outcomes of patients with drug-resistant tuberculosis should be improved through optimizing the use of f luoroquinolones, repurposed agents and newly developed drugs. In this context, the safety and tolerance of new therapeutic approaches must be addressed.

Keywords

References

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