한국섬유공학회지 (Textile Science and Engineering)

  • 제53권2호
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  • Pages.75-82
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  • 2016
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  • 1225-1089(pISSN)
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  • 2288-6419(eISSN)
한국섬유공학회 (The Korean Fiber Society)
권호 표지
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이중전기방사법을 이용한 키토산/PVA 나노섬유 웹과 필름의 제조 및 특성

Preparation of Chitosan/PVA Nanofiber Web and Film Using Co-electrospinning and Their Properties

  • 김은현 (영남대학교 나노메디컬유기재료공학과) ;
  • 김준호 (영남대학교 나노메디컬유기재료공학과)
  • Kim, EunHyun (Department of Nano, Medical and Polymer Materials, Yeungnam University) ;
  • Kim, Joon Ho (Department of Nano, Medical and Polymer Materials, Yeungnam University)
  • 투고 : 2015.12.15
  • 심사 : 2016.03.14
  • 발행 : 2016.04.30
⟨ 이전 논문 다음 논문 ⟩

초록

Polyvinyl alcohol (PVA) is a non-toxic, water-soluble, biocompatible, and biodegradable synthetic polymer, which is widely used in the biomedical field. As one of the most abundant natural polysaccharides, chitosan is well known for its biocompatible and biodegradable properties. Blended chitosan/PVA nanofiber webs and films were investigated for applications in the biomedical field. Pure chitosan nanofiber web, blended nanofiber web, and skin-core nanofiber webs were prepared by electrospinning. Chitosan/PVA blended films were prepared by the solution casting method. Scanning Electron Microscope photographs showed that the skin-core nanofiber web (chitosan skin, PVA core) had the best uniformity and was suitable for electrospinning. The PVA, chitosan, and blend films had better hydrophilicity and moisture regain than PVA, blend, and skin/core nanofibers. The FT-IR and DSC analyses demonstrated compatibility between PVA and chitosan. Also, nanofiber web and films with chitosan had better mechanical properties than pure PVA nanofiber web and film; the presence of chitosan reduced the tensile strength of nanofiber webs and films, but increased their Young's modulus. All nanofiber webs showed remarkably similar elongation, and chitosan was shown to reduce the elongation of films. This study concluded that blended chitosan/PVA nanofiber web and films are well suited for applications in medical materials, such as wound dressing.

키워드

참고문헌

  1. M. Carenza, "Recent Achievements in the Use of Radiation Polymerization and Grafting for Biomedical Applications", Radiat. Phys. Chem., 1992, 39, 485-493.
  2. H. Seo, K. Mitsuhashi, and H. Tanibe, "Antibacterial and Antifungal Fiber Blended by Chitosan", Elsevier Applied Science, London, 1992, pp.34-40.
  3. W. Park, K. Lee, J. Choi, W. Ha, and B. Chang, "Characterization of Chitosan-treated Wool Fabric(1)-Antimicrobial and Deodorant Activities", J. Korean Fiber Soc., 1996, 33, 855-860.
  4. M. Kong, X. G. Chen, C. S. Liu, C. G. Liu, X. H. Meng, and L. J. Yu, "Antibacterial Mechanism of Chitosan Microspheres in a Solid Dispersing System Against E. coli", Colloids and Surfaces B: Biointerfaces, 2008, 65, 197-202. https://doi.org/10.1016/j.colsurfb.2008.04.003
  5. Z. G. Chen, X. M. Mo, and F. L. Qing, "Electrospinning of Collagen-chitosan Complex", Mater. Lett., 2007, 61, 3490- 3494. https://doi.org/10.1016/j.matlet.2006.11.104
  6. B. Duan, C. H. Dong, X. Y. Yuan, and K. D. Yao, "Electrospinning of Chitosan Solutions in Acetic Acid with Poly(ethylene oxide)", J. Biomater. Sci., Polym. Ed., 2004, 15, 797-811. https://doi.org/10.1163/156856204774196171
  7. N. Bhattarai, D. Edmondson, O. Veiseh, F. A. Matsen, and M. Q. Zhang, “Electrospun Chitosan-based Nanofibers and Their Cellular Compatibility”, Biomaterials, 2005, 26, 6176-6184. https://doi.org/10.1016/j.biomaterials.2005.03.027
  8. S. Salmon and S. M. Hudson, "Crystal Morphology, Biosynthesis, and Physical Assembly of Cellulose, Chitin, and Chitosan", J. Macromol. Sci. Rev. Macromol. Chem., 1997, 37, 199-263.
  9. H. H. Lim, C. W. Nam, and S. W. Ko, "Spinning and Properties of Cellulose/Chitosan Blend Fiber", J. Korean Fiber Soc., 1997, 34, 444-449.
  10. X. Chen, W. Li, W. Zhong, Y. Lu, and T. Yu, "pH Sensitivity and Ion Sensitivity of Hydrogels Based on Complex-forming Chitosan/silk Fibroin Interpenetrating Polymer Network", J. Appl. Polym. Sci., 1997, 65, 2257-2262. https://doi.org/10.1002/(SICI)1097-4628(19970912)65:11<2257::AID-APP23>3.0.CO;2-Z
  11. J. Hosokawa, M. Nishiyama, K. Toshihara, T. Kubo, and A. Terabe, "Reaction between Chitosan and Cellulose on Biodegradable Composite Film Formation", Ind. Eng. Chem. Res., 1991, 30, 788-792. https://doi.org/10.1021/ie00052a025
  12. M. Hasegawa, A. Isogai, F. Onabe, M. Usuda, and R. H. Atalla, "Characterization of Cellulose-chitosan Blend Films", J. Appl. Polym. Sci., 1992, 45, 1873-1879. https://doi.org/10.1002/app.1992.070451101
  13. M. Hasegawa, A. Isogai, S. Kuga, and F. Onabe, “Preparation of Cellulose-chitosan Blend Film Using Chloral/Dimethylformamide”, Polymer, 1994, 35, 983-987. https://doi.org/10.1016/0032-3861(94)90942-3
  14. W. Y. Chuang, T. H. Young, C. H. Yao, and W. Y. Chiu, “Properties of the Poly(vinyl alcohol)/Chitosan Blend and Its Effect on the Culture of Fibroblast in vitro”, Biomaterials, 1999, 20, 1479-1487. https://doi.org/10.1016/S0142-9612(99)00054-X
  15. T. Koyano, N. Koshizaki, H. Umehara, M. Nagura, and N. Minoura, “Surface States of PVA/Chitosan Blended Hydrogels”, Polymer, 2000, 41, 4461-4465. https://doi.org/10.1016/S0032-3861(99)00675-8
  16. H. M. Kumar, M. N. Prabhakar, and C. V. Prasad, "Compatibility Studies of Chitosan/PVA Blend in 2% Aqueous Acetic Acid Solution at $30^{\circ}C$", Carbohydr. Polym., 2010, 82, 251-255. https://doi.org/10.1016/j.carbpol.2010.04.021
  17. A. L. Yarin, "Coaxial Electrospinning and Emulsion Electrospinning of Core-shell Fibers", Polym. Adv. Technol., 2011, 22, 310-317. https://doi.org/10.1002/pat.1781
  18. S. S. Ojiha, D. R. Stevens, and T. J. Hoffman, “Fabrication and Characterization of Electrospun Chitosan Nanofibers Formed via Templating with Polyethylene Oxide”, Biomacromolecules, 2008, 9, 2523-2529. https://doi.org/10.1021/bm800551q
  19. T. T. Nguyen, O. H. Chung, and J. S. Park, "Coaxial Electrospun Poly(lactic acid)/chitosan (core/shell) Composite Nanofibers and Their Antibacterial Activity", Carbohydr. Polym., 2011, 86, 1799-1806. https://doi.org/10.1016/j.carbpol.2011.07.014
  20. D. M. Spori, T. Drobek, S. Zurcher, M. Ochsner, C. Sprecher, A. Muhlebach, and N. D. Spencer, “Beyond the Lotus Effect: Roughness Influences on Wetting over a Wide Surface-Energy Range”, Langmuir, 2008, 24, 5411-5417. https://doi.org/10.1021/la800215r
  21. E. Bormashenko, "Why does the Cassie-Baxter Equation Apply?", Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2008, 324, 47-50.
  22. J. H. Kim, J. Y. Kim, Y. M. Lee, and K. Y. Kim, "Properties and Swelling Characteristics of Cross-linked Poly(vinyl alcohol)/chitosan Blend Membrane", J. Appl. Polym. Sci., 1992, 45, 1711-1717. https://doi.org/10.1002/app.1992.070451004
  23. L. Li, B. Li, M. A. Hood, and C. Y. Li, “Carbon Nanotube Induced Polymer Crystallization: The Formation of Nanohybrid Shish-kebabs”, Polymer, 2009, 50, 953-965. https://doi.org/10.1016/j.polymer.2008.12.031
  24. M. Avella and E. Martuscelli, "Poly-d-(-)(3-hydroxybutyrate)/poly(ethylene oxide) Blends: Phase Diagram, Thermal and Crystallization Behaviour", Polymer, 1988, 29, 1731-1737. https://doi.org/10.1016/0032-3861(88)90384-9
  25. J. H. Lee, C. H. Noh, H. W. Choi, Y. J. Jung, D. Y. Hwang, and E. P. Lee, "Fine Structure and Physical Properties of Chitosan/PVA Blend Films", Text. Sci. Eng., 2010, 47, 92-101.

피인용 문헌

  1. Fabrication and Changes in Physical and Functional Properties after Repeated Laundering of PU Nanocomposite Laminates Loaded with Electrospun Juniperus Chinensis Extracts vol.19, pp.11, 2018, https://doi.org/10.1007/s12221-018-8298-5