Journal of Korean Neurosurgical Society

  • 제59권1호
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  • Pages.65-68
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  • 2016
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  • 2005-3711(pISSN)
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  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
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Cervical Spondylotic Myelopathy due to the Ochronotic Arthropathy of the Cervical Spine

  • Li, Nan (Department of Spine Surgery, Beijing Jishuitan Hospital) ;
  • Tian, Wei (Department of Spine Surgery, Beijing Jishuitan Hospital) ;
  • Yuan, Qiang (Department of Spine Surgery, Beijing Jishuitan Hospital) ;
  • He, Da (Department of Spine Surgery, Beijing Jishuitan Hospital)
  • 투고 : 2014.08.27
  • 심사 : 2015.01.05
  • 발행 : 2016.01.01
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초록

Ochronosis is a musculoskeletal manifestation of alkaptonuria, a rare hereditary metabolic disorder occurs due to the absence of homogentisic acid oxidase and leading to various systemic abnormalities related to deposition of homogentisic acid pigmentation (ochronotic pigmentation). The present case reports the clinical features, radiographic findings, treatments and results of a cervical spondylotic myelopathy woman patient due to the ochronotic arthropathy of the cervical spine. The patient aged 62 years was presented with gait disturbance and hand clumsiness. Physical examination, X-rays, computed tomography and lab results of the urine sample confirmed the presence of ochronosis with the involvement of the cervical spine. The patient underwent a modified cervical laminoplasty due to multi-segment spinal cord compression. The postoperative follow-up showed a good functional outcome with patient satisfaction. The present study concludes the conditions and important diagnostic and surgical aspects of a patient. It is necessary to identify the condition clinically and if cord compression is observed, appropriate surgical interventions needs to be instituted.

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참고문헌

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피인용 문헌

  1. Ochronotic arthropathy—a rare clinical case vol.2018, pp.9, 2018, https://doi.org/10.1093/omcr/omy069
  2. “As Black as Ink”: A Case of Alkaptonuria-Associated Myelopathy and a Review of the Literature vol.44, pp.1, 2019, https://doi.org/10.1097/brs.0000000000002755
  3. Cervical Myelopathy Due to Ochronosis: An Intraoperative Suspicion vol.21, pp.None, 2016, https://doi.org/10.12659/ajcr.924575