Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Population-Based Intervention for Liver Fluke Prevention and Control in Meuang Yang District, Nakhon Ratchasima Province, Thailand

  • Published : 2016.03.07
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Abstract

Opisthorchiasis is still a major health problem in rural communities of Thailand. Infection is associated with cholangiocarcinoma (CCA), which is found frequently in Thailand, particularly in the northeastern. Therefore, this study aimed to evaluate the effectiveness of health intervention in the population at risk for opisthorchiasis and CCA. A quasi-experimental study was conducted in Meuang Yang district, Nakhon Ratchasima province, northeastern Thailand, between June and October 2015. Participants were completed health intervention comprising 4 stations; 1, VDO clip of moving adult worm of liver fluke; 2, poster of life cycle of liver fluke; 3, microscopy with adult and egg liver fluke; and 4, brochure with the knowledge of liver fluke containing infection, signs, symptoms, related disease, diagnosis, treatment, prevention, and control. Pre-and-post-test questionnaires were utilized to collect data from all participants. Students paired t-tests were used to analyze differences between before and after participation in the health intervention. Knowledge (mean difference=-7.48, t=-51.241, 95% CI, -7.77, -7.19, p-value =0.001), attitude (mean difference=-9.07, t=-9.818, 95% CI=-10.9, -7.24, p-value=0.001), and practice (mean difference=-2.04, t=-2.688, 95% CI=-3.55, -0.53, p-value=0.008), changed between before and after time points with statistical significance. Community rules were concluded regarding: (1) cooked cyprinoid fish consumption; (2) stop under cooked cyprinoid fish by household cooker; (3) cooked food consumption; (4) hygienic defecation; (5) corrected knowledge campaign close to each household; (6) organizing a village food safety club; (7) and annual health check including stool examination featuring monitoring by village health volunteers and local public health officers. The results indicates that the present health intervention program was effective and easy to understand, with low cost and taking only a short time. Therefore, this program may useful for further work at community and provincial levels for liver fluke prevention and control.

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References

  1. Bloom BS (1971). Handbook on formative and summative of student learning. New York: Mc Graw-Hill Book Company.
  2. Harinasuta C, Vajrasthira S (1960). Opisthorchiasis in Thailand. Am J Trop Med Hyg, 54, 100-5.
  3. Harinasuta T, Riganti M, Bunnag D (1984). Opisthorchis viverrini infection: pathogenesis and clinical features. Arzneimittelforschung, 34, 1167-9.
  4. IARC. (1994). Infection with liver flukes (Opisthorchis viverrini, Opisthorchis felineus and clonrochis sinensis). IARC Monogr Eval Carcinog Risks of Hum, 61, 121-75.
  5. Jongsuksuntigul P, Imsomboon T (2003). Opisthorchiasis control in Thailand. Acta Trop, 88, 229-32. https://doi.org/10.1016/j.actatropica.2003.01.002
  6. Kaewpitoon N, Kaewpitoon SJ, Pengsaa P, et al (2007). Knowledge, attitude and practice related to liver fluke infection in northeast Thailand. World J Gastroenterol, 13, 1837-40. https://doi.org/10.3748/wjg.v13.i12.1837
  7. Kaewpitoon N, Kaewpitoon SJ, Pengsaa P (2008). Opisthorchiasis in Thailand: review and current status. World J Gastroenterol, 14, 2297-302. https://doi.org/10.3748/wjg.14.2297
  8. Kaewpitoon N, Kaewpitoon SJ, Ueng-arporn N, et al (2012). Carcinogenic human liver fluke: current status of Opisthorchis viverrini metacercariae in Nakhon Ratchasima, Thailand. Asian Pac J Cancer Prev, 13, 1235-40. https://doi.org/10.7314/APJCP.2012.13.4.1235
  9. Kaewpitoon SJ, Rujirakul R, Ueng-Arporn N, et al (2012). Community-based cross-sectional study of carcinogenic human liver fluke in elderly from Surin province, Thailand. Asian Pac J Cancer Prev, 13, 4285-8. https://doi.org/10.7314/APJCP.2012.13.9.4285
  10. Kaewpitoon SJ, Rujirakul R, Kaewpitoon N (2012). Prevalence of Opisthorchis viverrini infection in Nakhon Ratchasima province, Northeast Thailand. Asian Pac J Cancer Prev, 13, 5245-9. https://doi.org/10.7314/APJCP.2012.13.10.5245
  11. Sadun EH (1995). Studies on Opisthorchis viverrini in Thailand. Am J Hyg, 62, 81-115.
  12. Sithithaworn P, Andrews RH, Nguyen VD, et al (2012). The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol International, 61, 10-6. https://doi.org/10.1016/j.parint.2011.08.014
  13. Sripa B, Kaewkes S, Intapan PM, et al (2010). Food-borne trematodiases in Southeast Asia: epidemiology, pathology, clinical manifestation and control. Adv Parasitol, 72, 305-50. https://doi.org/10.1016/S0065-308X(10)72011-X
  14. Sripa B, Brindley PJ, Mulvenna J, et al (2012). The tumorigenic liver fluke Opisthorchis viverrini-multiple pathways to cancer. Trends Parasitol, 28, 395-407. https://doi.org/10.1016/j.pt.2012.07.006
  15. Sripa B, Pairojkul C (2008). Cholangiocarcinoma: lessons from Thailand. Curr Opin Gastroenterol, 24, 349-56. https://doi.org/10.1097/MOG.0b013e3282fbf9b3
  16. Sripa B, Tangkawattana S, Laha T, et al (2015). Toward integrated opisthorchiasis control in northeast Thailand: The Lawa project. Acta Tropica, 141, 361-7 https://doi.org/10.1016/j.actatropica.2014.07.017
  17. Thamavit W, Bhamarapravati N, Sahaphong S, et al (1978). Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-infected Syrian golden hamsters. Cancer Res, 38, 4634-9.

Cited by

  1. Health Behavior Regarding Liver Flukes among Rural People in Nakhon Ratchasima, Thailand vol.17, pp.4, 2016, https://doi.org/10.7314/APJCP.2016.17.4.2111
  2. Effect of Educational Intervention Based on the Health Belief Model and Self-Efficacy in Promoting Preventive Behaviors in a Cholangiocarcinoma Screening Group pp.1543-0154, 2018, https://doi.org/10.1007/s13187-018-1424-7