Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Subcutaneous tissue calcification in a patient with rheumatoid arthritis

류마티스 관절염 환자에서 발생한 피하조직 석회화

  • Kim, Dong Hyun (Department of Internal Medicine, Busan St. Mary's Hospital) ;
  • Kim, Kyung Jin (Department of Internal Medicine, Busan St. Mary's Hospital) ;
  • Kwon, Sung Min (Department of Internal Medicine, Busan St. Mary's Hospital) ;
  • Cha, Sung Ouk (Department of Internal Medicine, Busan St. Mary's Hospital) ;
  • Lee, Jung Ouk (Department of Internal Medicine, Busan St. Mary's Hospital)
  • Received : 2015.04.03
  • Accepted : 2015.05.26
  • Published : 2016.11.18
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Abstract

Subcutaneous tissue calcification in rheumatic diseases usually occurs in connective tissue diseases, such as systemic lupus erythematosus, scleroderma, and dermatomyositis. Domestic cases of calcification in rheumatoid arthritis have not been reported. The mechanism of subcutaneous tissue calcification may differ depending on the cause and it can develop on all parts of the body. Calcification occurring in rheumatic diseases is a major mechanism of tissue damage caused by chronic inflammation. No standard therapy for calcification has been established; however, many studies have reported on medical and surgical treatment. We report on subcutaneous tissue calcification in a rheumatoid arthritis patient tissue calcification on both sides of the buttocks, the upper limbs, and the lower limbs.

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References

  1. Bolognia JL, Jorizzo JL, Rapini RP. Dermatology. 2nd ed. St. Louis, Mo: Mosby/Elsevier; 2008.
  2. Black AS, Kanat IO. A review of soft tissue calcifications. J Foot Surg 1985;24:243-50.
  3. Halverson PB, Ryan LM. Arthritis associated with calcium-containing crystals. In: Klippel JH, editor. Primer on the rheumatic diseases. 12th ed. Atlanta, GA: Arthritis Foundation; 2001. p. 299-306.
  4. Kwon KM, Park JH. A case of systemic lupus erythematosus coexistent with diffuse subcutaneous tissue calcification. J Korean Rheum Assoc 2000;7:77-82. Korean.
  5. Yi SW, Lee SW, Son MK, Kim YJ, Lee KH, Kang EJ, et al. Two cases of calcinosis cutis combined with rheumatologic disease. J Korean Rheum Assoc 2007;14:395-400. Korean. https://doi.org/10.4078/jkra.2007.14.4.395
  6. Nakamura T, Hirakawa K, Takaoka H, Iyama KI. Dystrophic calcinosis with both a huge calcified mass in the cervical spine and calcification in the chest wall in a patient with rheumatoid overlap syndrome. Clin Rheumatol 2016;35:1403-9. https://doi.org/10.1007/s10067-014-2696-x
  7. Boulman N, Slobodin G, Rozenbaum M, Rosner I. Calcinosis in rheumatic diseases. Semin Arthritis Rheum 2005;34:805-12. https://doi.org/10.1016/j.semarthrit.2005.01.016
  8. Minami A, Suda K, Kaneda K, Kumakiri M. Extensive subcutaneous calcification of the forearm in systemic lupus erythematosus. J Hand Surg Br 1994;19:638-41. https://doi.org/10.1016/0266-7681(94)90134-1
  9. Powell RJ. Systemic lupus erythematosus with widespread subcutaneous fat calcification. Proc R Soc Med 1974;67:215-7.
  10. Kim SY, Choi HY, Myung KB, Choi YW. The expression of molecular mediators in the idiopathic cutaneous calcification and ossification. J Cutan Pathol 2008;35:826-31. https://doi.org/10.1111/j.1600-0560.2007.00904.x
  11. Reiter N, El-Shabrawi L, Leinweber B, Berghold A, Aberer E. Calcinosis cutis: part II. Treatment options. J Am Acad Dermatol 2011;65:15-22. https://doi.org/10.1016/j.jaad.2010.08.039
  12. Berger RG, Featherstone GL, Raasch RH, McCartney WH, Hadler NM. Treatment of calcinosis universalis with low-dose warfarin. Am J Med 1987;83:72-6.
  13. Vereecken P, Stallenberg B, Tas S, de Dobbeleer G, Heenen M. Ulcerated dystrophic calcinosis cutis secondary to localised linear scleroderma. Int J Clin Pract 1998;52:593-4.
  14. Eddy MC, Leelawattana R, McAlister WH, Whyte MP. Calcinosis universalis complicating juvenile dermatomyositis: resolution during probenecid therapy. J Clin Endocrinol Metab 1997;82:3536-42.
  15. Mukamel M, Horev G, Mimouni M. New insight into calcinosis of juvenile dermatomyositis: a study of composition and treatment. J Pediatr 2001;138:763-6. https://doi.org/10.1067/mpd.2001.112473
  16. Morgan KW, Callen JP. Calcifying lupus panniculitis in a patient with subacute cutaneous lupus erythematosus: response to diltiazem and chloroquine. J Rheumatol 2001;28:2129-32.
  17. Dutz J. Treatment options for the cutaneous manifestations of systemic sclerosis. Skin Therapy Lett 2000;6:3-5.
  18. Bottomley WW, Goodfield MJ, Sheehan-Dare RA. Digital calcification in systemic sclerosis: effective treatment with good tissue preservation using the carbon dioxide laser. Br J Dermatol 1996;135:302-4. https://doi.org/10.1111/j.1365-2133.1996.tb01166.x
  19. MacLean C, Brahn E. Systemic lupus erythematosus: calciphylaxis induced cardiomyopathy. J Rheumatol 1995;22:177-9.