Journal of Mushroom (한국버섯학회지)

The Korean Society of Mushroom Science (한국버섯학회)
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Skin-whitening effects of hot water extract from domestic edible mushrooms

국내 시판 식용버섯 열수 추출물의 피부미백 기능 연구

  • Kim, Hyunjae (Department of Food Science & Biotechnology, Sungkyunkwan University) ;
  • Jang, Byunghyun (Department of Food Science & Biotechnology, Sungkyunkwan University) ;
  • Park, Kunhee (Department of Food Science & Biotechnology, Sungkyunkwan University) ;
  • Jang, Gabyeol (National Institute of Horticultural and Herbal Science) ;
  • Park, Kimoon (Department of Food Science & Biotechnology, Sungkyunkwan University)
  • 김현재 (성균관대학교 식품생명공학과) ;
  • 장병현 (성균관대학교 식품생명공학과) ;
  • 박건희 (성균관대학교 식품생명공학과) ;
  • 장갑열 (국립원예특작과학원) ;
  • 박기문 (성균관대학교 식품생명공학과)
  • Received : 2016.11.19
  • Accepted : 2016.12.21
  • Published : 2016.12.31
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Abstract

Hot water extracts from 16 domestic edible mushrooms including Pleurotus ferulae (Lanzi) X.L. Mao, Lentinula edodes (Berk.) Pegler, and Hypsizygus marmoreus (Peck) H.E. Bigelow, which are commercially available, were used for determining the cosmetic potential of these mushrooms. In this study, we carried out in vitro functional experiments to determine the inhibitory effects of these extracts on L-DOPA oxidation of tyrosinase and melanin synthesis. Based on the results of these experiments, H. marmoreus (Peck) H.E. Bigelow No. 10 and No. 15 were selected for further analysis. We analyzed the melanin synthesis inhibitory activity, TRP1 and MITF expression via real-time PCR, and Fontana Masson staining in artificial skin $Neoderm^{(R)}-ME$. Taken together, we observed that the hot water extract from H. marmoreus (Peck) H.E. Bigelow (No. 15) had better whitening effect than the extracts of other mushrooms. Thus, it can be a potential source of skin-whitening agent.

국내시판 식용버섯의 16종의 열수 추출물을 이용하여 L-DOPA oxidation activity, melanin 합성 억제활성을 통해 미백에 가장 효능이 우수한 버섯으로 갈색백만송이버섯 (No. 10)과 흰색만가닥버섯 (No. 15)를 선별하였다. 또 멜라닌 세포와 표피가 재현된 인공피부를 이용하여 이 두 가지 버섯 열수 추출물의 미백 효과를 확인한 결과 흰색만가닥버섯 (No. 15)이 가장 우수함을 확인하였다.

Keywords

References

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