Korean Journal of Psychosomatic Medicine (정신신체의학)

Korean Psychosomatic Society (한국정신신체의학회)
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Associations between Vasomotor Symptoms and Depression, Stress and Quality of Life in Midlife Women

중년여성에서의 혈관운동증상과 우울, 스트레스, 삶의 질과의 상관성

  • Nam, Yoon-Min (Department of Psychiatry, Korea University College of Medicine) ;
  • Joe, Sook-Haeng (Department of Psychiatry, Korea University College of Medicine) ;
  • Kwon, Eun-Joo (Health Promotion Research Institute, Korea Association of Health Promotion) ;
  • Ham, Byung-Joo (Department of Psychiatry, Korea University College of Medicine) ;
  • Han, Chang-Su (Department of Psychiatry, Korea University College of Medicine) ;
  • Ko, Young-Hoon (Department of Psychiatry, Korea University College of Medicine)
  • 남윤민 (고려대학교 의과대학 정신건강의학교실) ;
  • 조숙행 (고려대학교 의과대학 정신건강의학교실) ;
  • 권은주 (한국건강관리협회 건강증진연구소) ;
  • 함병주 (고려대학교 의과대학 정신건강의학교실) ;
  • 한창수 (고려대학교 의과대학 정신건강의학교실) ;
  • 고영훈 (고려대학교 의과대학 정신건강의학교실)
  • Received : 2016.07.13
  • Accepted : 2016.12.05
  • Published : 2016.12.31
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Abstract

Objectives : The aim of this study was to evaluate the associations between vasomotor symptoms and factors such as sociodemographics, health behaviors, medical condition, depression, stress, anxiety, attitude toward menopause, and quality of life. Methods : We conducted a cross-sectional study in peri- and post-menopausal women enrolled by the Korean Association of Health Promotion. Subjects submitted self-report questionnaires about vasomotor symptoms and other clinical symptoms. Associations between vasomotor symptoms and clinical variables were analyzed using stepwise multiple regression analyses. Results : 1951 women completed self-report questionnaires and 1022 women were enrolled in the study. The prevalence of vasomotor symptoms in peri- and post-menopausal women was 63.9%. Variables showing significant differences between subjects with vasomotor symptoms and subjects without them were score of Beck Depression Inventory, Brief Encounter Psychosocial Instrument-Korean Version, proportions of clinically significant depression(Beck Depression Inventory ${\geq}16$), Menopausal rating scale, attitude towards menopause, the 4 subscales of World Health Organization Quality of Life-BREF(Physical health, psychological, social relationships, environment), and a History of Premenstrual syndrome/Premenstrual dysphoric disorder. Stepwise multiple regression analyses indicated that Beck Depression Inventory, Brief Encounter Psychosocial Instrument-Korean Version, Menopausal Rating Scale, and the Psychological subscale of World Health Organization Quality of Life -BREF show associations with vasomotor symptoms. Conclusions : Menopausal vasomotor symptoms are associated with various psychological factors, especially with depression. Midlife women suffering vasomotor symptoms should therefore be screened for depression. Future prospective studies where clinical subjects are diagnosed using structured interviews, focusing on the causal relationship between depression and vasomotor symptoms are necessary.

연구목적 본 연구의 목적은 폐경주위기, 폐경 후기 여성에서 혈관운동증상과 인구통계학적 변인들과 건강행태, 내과적 질환, 우울, 스트레스, 불안, 폐경에 대한 태도 및 삶의 질과의 관계를 규명하는 것이다. 방 법 한국건강관리협회에 건강검진을 위해 방문한 중년 여성을 대상으로 단면조사연구를 실시하였다. 대상자는 혈관운동증상과 관련 요인에 대한 자가보고 설문지를 작성하였다. 혈관운동증상과 요소들간의 상관관계가 분석되었다. 통계 분석에는 SPSS를 사용하였다. 결 과 폐경주위기 및 폐경후기 여성의 혈관운동증상의 발생률은 63.9%로 나타났다. 혈관운동증상 유무에 따른 유의한 차이를 보인 변인들은 BDI, BEPSI-K, 임상적으로 유의한 우울증상을 보이는 군의 비율($BDI{\geq}16$), 폐경증상척도, Attitude toward menopause, WHOQOL_BREF의 4개의 부척도(신체적 건강, 심리적, 사회적 관계, 환경), 그리고 PMS/PMDD의 과거력이었다. 이 중 다중 회귀분석에서 유의한 상관성을 보인 요인은 BDI, BEPSI-K, 폐경증상척도, WHOBREF 부척도 중 심리적 척도였다. 결 론 폐경기의 혈관운동증상은 심리적 요인 및 정신사회적 요인들과 상관관계를 보이는 것을 확인하였다. 특히 우울증상간의 밀접한 상관관계를 확인할 수 있었으며, 혈관운동증상을 보이는 중년여성군에서 우울증에 대한 선별검사가 필요할 것이다. 추후 명확한 인과관계를 파악하기 위해 임상군을 대상으로 보다 구조화된 진단을 통해 혈관운동증상과 우울증간의 전향적 연구가 필요할 것이다.

Keywords

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