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Swelling Properties of Carboxymethylcellulose Hydrogels Prepared by Electron Beam Irradiation

전자선 조사를 통해 제조한 카복시메틸셀룰로스 수화젤의 팽윤거동

  • Kim, Min Hee (Department of Advanced Organic Materials and Textile System Engineering, Chungnam National University) ;
  • Cho, Donghwan (Department of Polymer Science and Engineering, Kumoh National Institute of Technology) ;
  • Kwon, Oh Hyeong (Department of Polymer Science and Engineering, Kumoh National Institute of Technology) ;
  • Park, Won Ho (Department of Advanced Organic Materials and Textile System Engineering, Chungnam National University)
  • 김민희 (충남대학교 공과대학 유기소재.섬유시스템공학과) ;
  • 조동환 (금오공과대학교 화학소재융합학부 고분자융합소재공학과) ;
  • 권오형 (금오공과대학교 화학소재융합학부 고분자융합소재공학과) ;
  • 박원호 (충남대학교 공과대학 유기소재.섬유시스템공학과)
  • Received : 2016.10.19
  • Accepted : 2016.11.30
  • Published : 2016.12.31

Abstract

In this study, carboxymethylcellulose (CMC) hydrogels were successfully prepared by electron beam irradiation. The morphology and mechanical properties of the hydrogels were examined by scanning electron microscopy and tensile testing, which indicated that the compressive strength of the hydrogels was closely associated with their pore wall thickness. In addition, the equilibrium swelling ratio of the hydrogels was evaluated in both distilled water and different physiological media, which indicated that their maximum swelling ratio was higher in water than that in physiological media. Moreover, their maximum swelling ratio decreased with an increase in salt concentration. The fabricated cellulose-based hydrogels were shown to be promising for applications in drug delivery systems and the field of biomaterials.

Keywords

Acknowledgement

Supported by : 미래창조과학부

References

  1. T. H. Kim and Y. C. Nho, "Synthesis of PVA/PVP Hydrogel by Irradiation Crosslinking", J. Appl. Polym. Sci., 2001, 25, 270-278.
  2. J. K. Kim, C. Basavaraja, T. Yamaguchi, and D. S. Huh, "Preparation and Characterization of Smart Hydrogel Nanocomposites Sensitive to Oxidation-Reduction", Polym. Bull., 2013, 70, 207-220. https://doi.org/10.1007/s00289-012-0825-8
  3. W. E. Hennink and C. F. van Nostrum, "Novel Crosslinking Methods to Design Hydrogels", Adv. Drug Deliver. Rev., 2002, 54, 13-36. https://doi.org/10.1016/S0169-409X(01)00240-X
  4. M. Bianconi, E. Albertazzi, S. Balboni, L. Colombo, G. Lulli, and A. Satta, "Channeling Characterization of Defects in Silicon: An Atomistic Approach", Nucl. Instrum. Meth. B, 2005, 230, 185-192. https://doi.org/10.1016/j.nimb.2004.12.038
  5. J. H. Cho, Y. J. Lee, Y. M. Lim, P. H. Kang, J. Shin, and Y. C. Nho, "Radiation Processing of Polymeric Materials", Polym. Sci. Tech., 2007, 18, 253-258.
  6. M. H. Kim and W. H. Park, "Chemically Cross-linked Silk Fibroin Hydrogel with Enhanced Elastic Properties, Biodegradability, and Biocompatibility", Int. J. Nanomed., 2016, 11, 2967-2978.
  7. K. Makuuchi and S. Keizo, "Radiation Processing of Polymer Materials and Its Industrial Applications", John Wiley & Sons, NY, 2012, pp.103-130.
  8. A. Sannino, C. Demitri, and M. Madaghiele, "Biodegradable Cellulose-based Hydrogels: Design and Applications", Materials, 2009, 2, 353-373. https://doi.org/10.3390/ma2020353
  9. J. H. Chang, K. Park, J. W. Park, J. K. Shin, T. Kajiuchi, and Y. Shinya, "Characteristics of Carboxymethylcellulose(CMC) Using Regenerated Cellulose Fiber", Applied Chemistry, 2002, 6, 567-570.
  10. D. Zhao, G. Liao, G. Gao, and F. Liu, "Influences of Intramolecular Cyclization on Structure and Cross-linking Reaction Processes of PVA Hydrogels", Macromolecules, 2006, 39, 1160-1164. https://doi.org/10.1021/ma052419l
  11. R. A. Wach, H. Mitomo, F. Yoshii, and T. Kume, "Hydrogel of Biodegradable Cellulose Derivatives. II. Effect of Some Factors on Radiation-Induced Cross-linking of CMC", J. Appl. Polym. Sci., 2001, 81, 3030-3037. https://doi.org/10.1002/app.1753
  12. C. Chang, B. Duan, J. Cai, and L. Zhang, "Superabsorbent Hydrogels Based on Cellulose for Smart Swelling and Controllable Delivery", Eur. Polym. J., 2010, 46, 92-100. https://doi.org/10.1016/j.eurpolymj.2009.04.033