DOI QR코드

DOI QR Code

Sleep Quality and Associated Risk Factors in Leukemia Patients Undergoing Chemotherapy in Iran

  • Bagheri-Nesami, Masoumeh (Department of Medical-Surgical Nursing, Mazandaran Pediateric Infectious Disease Research Center (MPIDRC)) ;
  • Goudarzian, Amir Hossein (Student Research Committee, Mazandaran University of Medical Sciences) ;
  • Babaei, Ghasem Jan (Cancer Research Center, Department of Oncology, Mazandaran University of Medical Sciences) ;
  • Badiee, Milad (Student Research Committee, Mazandaran University of Medical Sciences) ;
  • Mousavi, Mostafa (Student Research Committee, Mazandaran University of Medical Sciences) ;
  • Sharifi, Mohammad Sadegh (Student Research Committee, Mazandaran University of Medical Sciences)
  • Published : 2016.06.01

Abstract

This study aimed to determine sleep disorders and associated risk factors in leukemia patients undergoing chemotherapy in Imam Khomeini Hospital of Sari, Iran. This cross-sectional study was conducted in 2015 with 100 patients selected. Inclusion criteria included complete mental and psychological health and being over 18 years old, and exclusion criteria included suffering other cancers, other chronic diseases, concurrent radiotherapy, and chemotherapy. The Pittsburgh Sleep Quality standard questionnaire was used to collect data. The questionnaire consisted of mental sleep quality, sleep latency, sleep duration, sleep quality, sleep disturbances, use of sleeping drugs, and impaired daily functioning. Data were analyzed by software SPSS 18 and by using descriptive and inferential tests (Pearson, Spearman, T-test and chi-square). Totals of 47 men (47%) and 53 women (53%) with a mean age of $44.1{\pm}1.7$, participated in the study. The mean overall score of sleep quality was $9.3{\pm}3.9$, which represents the average sleep quality in most participants. T-test shows that males have better sleep quality than females (t=2.1; 95%CI:0.004-0.25; P<0.01). Also the sleep quality increased with age (r=0.22, P=0.03). Results show that the amount of sleep quality was only moderate in most patients, so it is necessary to take coping strategies to improve their quality of sleep.

Keywords

References

  1. Anderson KO, Getto CJ, Mendoza TR, et al (2003). Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adults. J Pain Symptom Manage, 25, 307-18. https://doi.org/10.1016/S0885-3924(02)00682-6
  2. Björnsdóttir E, Janson C, Sigurdsson JF, et al (2013). Symptoms of insomnia among patients with obstructive sleep apnea before and after two years of positive airway pressure treatment. Sleep, 36, 1901-9. https://doi.org/10.5665/sleep.3226
  3. Baglioni C, Battagliese G, Feige B, et al (2011). Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord, 135, 9-10.
  4. Buysse DJ, Reynolds CF, Monk TH, et al (1989). The pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res, 28, 193-213. https://doi.org/10.1016/0165-1781(89)90047-4
  5. Beck SL, Berger AM, Barsevick AM, et al (2010). Sleep quality after initial chemotherapy for breast cancer. Support Care Cancer, 18, 679-89. https://doi.org/10.1007/s00520-009-0662-y
  6. Chao YH, Sheu JN, Chen SM, et al (2013). Diagnostic paracentesis in an acute lymphoblastic leukemia child without characteristic symptoms of pancreatitis. J Pediatr Hematol Oncol, 35, 47. https://doi.org/10.1097/MPH.0b013e31825884f9
  7. Cohen L, Warnek C, Rachel Fouladi R, et al (2004). Psychological adjustment and sleep quality randomized of the effects of atibet a yoga intervention in patients with lymphoma. Cancer, 100, 2253-60. https://doi.org/10.1002/cncr.20236
  8. Dogan O, Ertekin S, Dogan S (2005). Sleep quality in hospitalized patients. J Clin Nurs, 14, 107-13. https://doi.org/10.1111/j.1365-2702.2004.01011.x
  9. Dean GE, Redeker NS, Wang Y, et al (2013). Sleep, Mood, and Quality of Life in Patients Receiving Treatment for Lung Cancer. Oncol Nurs Forum, 40, 441-51. https://doi.org/10.1188/13.ONF.441-451
  10. Elizabeth Venables H (2014). Sleep problems in cancer: effective psychological interventions- a systematic review. Res Medica, 22, 15-36. https://doi.org/10.2218/resmedica.v22i1.776
  11. Farrahi Moghaddam J, Nakhaee N, Sheibani V, et al (2012). Reliability and validity of the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P). Sleep Breath, 16, 79-82. https://doi.org/10.1007/s11325-010-0478-5
  12. Greenberg EM, Probst A (2013). Chronic Leukemia. Crit Care Nurs Clin North Am, 25, 459-70. https://doi.org/10.1016/j.ccell.2013.09.003
  13. Gözdaşoğlu S, Yavuz G, Unal E, et al (2002). Orbital granulocytic sarcoma and AML with poor prognosis in Turkish children. Leukemia, 16, 962. https://doi.org/10.1038/sj.leu.2402449
  14. Gooneratne NS, Dean GE, Rogers AE, et al (2007). Sleep and quality of life in long-term lung cancer survivors. Lung Cancer, 58, 403-10. https://doi.org/10.1016/j.lungcan.2007.07.011
  15. Ghanbari Jolfaei A, Makvandi A, Pazouki A (2014). Quality of sleep for hospitalized patients in Rasoul-Akram hospital. Med J Islam Repub Iran, 28, 73-8
  16. He Y, Meng Z, Jia Q, et al (2015). Sleep quality of patients with differentiated thyroid cancer. PLoS One, 10, e013063-4.
  17. Hasanpour Dehkordi A (2006). Factors affecting quality of life in cancer patients under chemotherapy in Tehran (2004). J Kermanshah Univ Med Sci, 10, 110-9.
  18. Kaspers GJ, Zwaan CM (2007). Pediatric acute myeloid leukemia: towards high-quality cure of all patients. Haematologica, 92, 1519-32. https://doi.org/10.3324/haematol.11203
  19. Kaleyias J, Manley P, Kothare SV (2012). Sleep disorders in children With cancer. Semin Pediatr Neurol, 19, 25-34. https://doi.org/10.1016/j.spen.2012.02.013
  20. Moller T, Adamsen L, Appel C, et al (2012). Health related quality of life and impact of infectious comorbidity in outpatient management of patients with acute leukemia. Leuk Lymphoma, 53, 1896-904. https://doi.org/10.3109/10428194.2012.676169
  21. Mystakidou K, Parpa E, Tsilika E, et al (2007). The relationship of subjective sleep quality, pain, and quality of life in advanced cancer patients. Sleep, 30, 737-42. https://doi.org/10.1093/sleep/30.6.737
  22. Norozi M (2012). Quality of sleep and related factor in breast cancer patients receving chemotherapy in Qom 2011. Iran J Breast Dis, 4, 51-60.
  23. Palesh OG, Roscoe JA, Mustian KM, et al (2010). Prevalence, demographics, and psychological associations of sleep disruption in patients with cancer: University of Rochester Cancer Center-Community Clinical Oncology Program. J Clin Oncol, 28, 292-8. https://doi.org/10.1200/JCO.2009.22.5011
  24. Rayar MS, Nayiager T, Webber CE, et al (2012). Predictors of bony morbidity in children with acute lymphoblastic leukemia. Pediatr Blood Cancer, 59, 77-82. https://doi.org/10.1002/pbc.24040
  25. Smith MA, Altekruse SF, Adamson PC, et al (2013). Declining childhood and adolescent cancer mortality. Cancer, 120, 2497-506.
  26. Savard J, Simard S, Blanchet J, et al (2001). Prevalence, clinical characteristics, and risk factors for insomnia in the context of breast cancer. Sleep, 24, 583-90. https://doi.org/10.1093/sleep/24.5.583
  27. Tahmasebi B, Mahmoudi M, Yahya Pour Y, et al (2006). Determination and comparison of incidence rate and trend of morbidity of leukemia and lymphoma in Mazandaran province. J Mazandaran Univ Med Sci, 16, 87-9.
  28. Zhang J, Li F, Lin Y, et al (2007). Subjective sleep quality in perimenopausal women and its related factors. J Nanjing Med Univ, 21, 116-9. https://doi.org/10.1016/S1007-4376(07)60028-8

Cited by

  1. Factors Affecting Sleep Disturbances in Hospitalized Patients with Colorectal Cancer undergoing Chemotherapy: A Retrospective Study vol.31, pp.1, 2019, https://doi.org/10.7475/kjan.2019.31.1.100