Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Clinical Characteristics of Patients after Aryloxyphenoxy Propionate Herbicide Ingestion

Aryloxyphenoxy propionate 계열 제초제 중독환자의 임상 양상

  • Lim, Junyeong (Department of Emergency Medicine, Chonnam National University Medical School) ;
  • Moon, Jeongmi (Department of Emergency Medicine, Chonnam National University Medical School) ;
  • Chun, Byeongjo (Department of Emergency Medicine, Chonnam National University Medical School)
  • 임준영 (전남대학교 의과대학 응급의학교실) ;
  • 문정미 (전남대학교 의과대학 응급의학교실) ;
  • 전병조 (전남대학교 의과대학 응급의학교실)
  • Received : 2016.08.19
  • Accepted : 2016.09.12
  • Published : 2016.12.31
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Abstract

Purpose: No studies have been conducted to investigate the acute toxicity of aryloxyphenoxypropionate herbicides in humans following ingestion. Therefore, this study was conducted to investigate the clinical characteristics of aryloxyphenoxypropionate herbicide poisoning and provide guidance for physicians treating patients who have ingested these types of herbicides. Methods: A retrospective observational case series was conducted using ten patients with history of aryloxyphenoxy propionate herbicide. Data were collected for clinical manifestation, management and final outcome. Results: The most common symptoms were gastrointestinal irritation and an altered mental state (Glasgow Coma Scale<15). An elevated lactate level was a common laboratory abnormality, and prolonged QTc interval was commonly observed. These clinical features normalized within one day of supportive treatment. Conclusion: The acute toxicity of aryloxyphenoxypropionate herbicides in humans is manageable with supportive treatment. However, physicians should take into account depressed consciousness, the possibility of arrhythmia, and an elevated lactate level when planning their treatment strategy.

Keywords

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