References
- Hansson GK, Libby P. Inflammation and immunity in diseases of the arterial tree: players and layers. Circ Res. 2015;116:307-311. https://doi.org/10.1161/CIRCRESAHA.116.301313
- Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006;6:508-519. https://doi.org/10.1038/nri1882
- Hilgendorf I, Swirski FK, Robbins CS. Monocyte fate in atherosclerosis. Arterioscler Thromb Vasc Biol. 2015;35:272-279. https://doi.org/10.1161/ATVBAHA.114.303565
- Allahverdian S, Chehroudi AC, McManus BM, Abraham T, Francis GA. Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis. Circulation. 2014;129:1551-1559. https://doi.org/10.1161/CIRCULATIONAHA.113.005015
- Rong JX, Shapiro M, Trogan E, Fisher EA. Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading. Proc Natl Acad Sci U S A. 2003;100:13531-13536. https://doi.org/10.1073/pnas.1735526100
- Vengrenyuk Y, Nishi H, Long X, Ouimet M, Savji N, Martinez FO, et al. Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype. Arteriosclerosis Thrombosis Vasc Biol. 2015;35:535-546. https://doi.org/10.1161/ATVBAHA.114.304029
- Feil S, Fehrenbacher B, Lukowski R, Essmann F, Schulze-Osthoff K, Schaller M, et al. Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis. Circ Res. 2014;115:662-667. https://doi.org/10.1161/CIRCRESAHA.115.304634
- Rudel LL, Lee RG, Cockman TL. Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr Opin Lipidol. 2001;12:121-127. https://doi.org/10.1097/00041433-200104000-00005
- Pedersen TR. The success story of LDL cholesterol lowering. Circ Res. 2016;19;118:721-731. https://doi.org/10.1161/CIRCRESAHA.115.306297
- Lee JS, Bok SH, Park YB, Lee MK, Choi MS. 4-Hydroxycinnamate lowers plasma and hepatic lipids without changing antioxidant enzyme activities. Ann Nutr Metab. 2003;47:144-151. https://doi.org/10.1159/000070037
- Kusunoki J, Hansoty DK, Aragane K, Fallon JT, Badimon JJ, Fisher EA. Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2001;103:2604-2609. https://doi.org/10.1161/01.CIR.103.21.2604
- Buhman KF, Accad M and Farese RV. Mammalian acyl-CoA: cholesterol acyltransferases. Biochim Biophys Acta. 2000;1529:142-154. https://doi.org/10.1016/S1388-1981(00)00144-X
- Fazio S, Major AS, Swift LL, Gleaves LA, Accad M, Linton MF, et al. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J Clin Invest. 2001;107:163-171. https://doi.org/10.1172/JCI10310
- Wu C, Luan H, Zhang X, Wang S, Zhang X, Sun X, et al. Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages. PLoS One. 2014;4:e95452.
- Noguchi N, Niki E. Phenolic antioxidants: a rationale for design and evaluation of novel antioxidant drug for atherosclerosis. Free Radic Biol Med. 2000;28:1538-1546. https://doi.org/10.1016/S0891-5849(00)00256-2
-
Xu ZR, Li JY, Dong XW, Tan ZJ, Wu WZ, Xie QM, et al. Apple polyphenols decrease atherosclerosis and hepatic steatosis in ApoE-/- mice through the
$ROS/MAPK/NF-{\kappa}B$ pathway. Nutrients. 2015;7:7085-7105. https://doi.org/10.3390/nu7085324 - Nardini M, D'Aquino M, Tomassi G, Gentili V, Di Felice M, Scaccini C. Inhibition of human low-density lipoprotein oxidation by caffeic acid and other hydroxycinnamic acid derivatives. Free Radical Biol Med. 1995;19:541-552. https://doi.org/10.1016/0891-5849(95)00052-Y
- Tanaka T, Kojima T, Kawamori T, Wang A, Suzui M, Okamoto K, et al. Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ellagic, chlorogenic and ferulic acids. Carcinogenesis. 1993;14:1321-1325. https://doi.org/10.1093/carcin/14.7.1321
- Lee JS, Choi MS, Jeon SM, Jeong TS, Park YB, Lee MK, et al. Lipid-lowering and antioxidative activities of 3,4-di(OH)- cinnamate and 3,4-di(OH)-hydrocinnamate in cholesterol-fed rats. Clin Chim Acta. 2001;314:221-229. https://doi.org/10.1016/S0009-8981(01)00700-8
- Erickson SK, Shrewsbury MA, Brooks C, Meyer DJ. Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro. J Lipid Res. 1980;21:930-941.
- Gillies PJ, Rathgeb KA, Perri MA, Robinson CS. Regulation of acyl-CoA:cholesterol acyltransferase activity in normal and atherosclerotic rabbit aortas: role of a cholesterol substrate pool. Exp Mol Pathol. 1986;44:329-339. https://doi.org/10.1016/0014-4800(86)90046-8
- Russell JC, Proctor SD. Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis. Cardiovascular Pathology. 2006;15:318-330. https://doi.org/10.1016/j.carpath.2006.09.001
- Ikenoya M, Yoshinaka Y, Kobayashi H, Kawamine K, Shibuya K, Sato F. A selective ACAT-1 inhibitor, K-604, suppresses fatty streak lesions in fat-fed hamsters without affecting plasma cholesterol levels. Atherosclerosis. 2007;191:290-297. https://doi.org/10.1016/j.atherosclerosis.2006.05.048
- Tauchi Y, Yoshimi A, Shirahase H, Sato J, Ito K, Morimoto K. Inhibitory effect of acyl-CoA:cholesterol acyltransferase inhibitor-low density lipoprotein complex on experimental atherosclerosis. Biol Pharm Bull. 2003;26:73-78. https://doi.org/10.1248/bpb.26.73
- Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P. Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med. 2006;354:1253-1263. https://doi.org/10.1056/NEJMoa054699
- Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010;464:1357-1361. https://doi.org/10.1038/nature08938
- Rong JX, Blachford C, Feig JE, Bander I, Mayne J, Kusunoki J. ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity. Arterioscler Thromb Vasc Biol. 2013;33:4-12. https://doi.org/10.1161/ATVBAHA.112.252056
- Yoshinaka Y, Shibata H, Kobayashi H, Kuriyama H, Shibuya K, Tanabe S. A selective ACAT-1 inhibitor, K-604, stimulates collagen production in cultured smooth muscle cells and alters plaque phenotype in apolipoprotein E-knockout mice. Atherosclerosis. 2010;213:85-91. https://doi.org/10.1016/j.atherosclerosis.2010.08.048
Cited by
- PI3K, Akt, p38을 포함한 인산화단백질에 대한 Cordycepin의 억제효과 vol.49, pp.2, 2016, https://doi.org/10.15324/kjcls.2017.49.2.99