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A Case of Primary Adenosquamous Carcinoma of the True Vocal Fold Mimicking Atypical Squamous Cell Proliferation

비정형 편평세포 증식으로 오인된 진성대의 원발성 선편평세포암종

  • Kim, Ju Yeon (Department of Otolaryngology-Head and Neck Surgery, Ewha Womans University, School of Medicine) ;
  • Chun, Mi Sun (Department of Otolaryngology-Head and Neck Surgery, Ewha Womans University, School of Medicine) ;
  • Jung, Soo Yeon (Department of Otolaryngology-Head and Neck Surgery, Ewha Womans University, School of Medicine) ;
  • Kim, Han Su (Department of Otolaryngology-Head and Neck Surgery, Ewha Womans University, School of Medicine)
  • 김주연 (이화여자대학교 의학전문대학원 이비인후과학교실) ;
  • 천미선 (이화여자대학교 의학전문대학원 이비인후과학교실) ;
  • 정수연 (이화여자대학교 의학전문대학원 이비인후과학교실) ;
  • 김한수 (이화여자대학교 의학전문대학원 이비인후과학교실)
  • Received : 2016.08.16
  • Accepted : 2016.11.03
  • Published : 2016.11.30

Abstract

Adenosquamous carcinoma (ASC) of the larynx is very rare malignancy which has well defined two distinctive pathological features, an adenocarcinoma and a squamous cell carcinoma (SCC). Diagnosis of ASC by endoscopic biopsy is challenging due to small amount of harvested tissue. ASC has a worse prognosis than SCC with an early lymph node metastasis and a distant dissemination. We experienced a rare case of vocal fold ASC which was initially misdiagnosed as atypical squamous cell proliferation at frozen biopsy. We reported this case with a literature review.

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