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Sclerosing Pneumocytoma with a Wax-and-Wane Pattern of Growth: A Case Report on Computed Tomography and Magnetic Resonance Imaging Findings and a Literature Review

  • Kim, Yong Pyo (Department of Radiology and the Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Lee, Sungsoo (Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Park, Heae Surng (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Park, Chul Hwan (Department of Radiology and the Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Tae Hoon (Department of Radiology and the Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine)
  • Received : 2014.08.18
  • Accepted : 2015.04.21
  • Published : 2015.08.01

Abstract

Sclerosing pneumocytoma (SP) of the lung is a rare benign neoplasm. Here, we describe an unusual presentation of SP with a wax-and-wane pattern of growth in a 47-year-old woman. Tumor diameter decreased over a 3-year follow-up period and then increased on serial follow-up computed tomography scans. The mass showed high signal intensity on both T1- and T2-weighted chest magnetic resonance imaging (MRI) and early enhancement with a plateau on dynamic MRI. We speculate that intratumoral bleeding and resorption processes accounted for the changes in tumor size.

Keywords

References

  1. Illei PB, Rosai J, Klimstra DS. Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung. Arch Pathol Lab Med 2001;125:1335-1339
  2. Devouassoux-Shisheboran M, Hayashi T, Linnoila RI, Koss MN, Travis WD. A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium. Am J Surg Pathol 2000;24:906-916 https://doi.org/10.1097/00000478-200007000-00002
  3. Fujiyoshi F, Ichinari N, Fukukura Y, Sasaki M, Hiraki Y, Nakajo M. Sclerosing hemangioma of the lung: MR findings and correlation with pathological features. J Comput Assist Tomogr 1998;22:1006-1008 https://doi.org/10.1097/00004728-199811000-00031
  4. Kim GY, Kim J, Choi YS, Kim HJ, Ahn G, Han J. Sixteen cases of sclerosing hemangioma of the lung including unusual presentations. J Korean Med Sci 2004;19:352-358 https://doi.org/10.3346/jkms.2004.19.3.352
  5. Liebow AA, Hubbell DS. Sclerosing hemangioma (histiocytoma, xanthoma) of the lung. Cancer 1956;9:53-75 https://doi.org/10.1002/1097-0142(195601/02)9:1<53::AID-CNCR2820090104>3.0.CO;2-U
  6. Miyagawa-Hayashino A, Tazelaar HD, Langel DJ, Colby TV. Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases. Arch Pathol Lab Med 2003;127:321-325
  7. Kalhor N, Staerkel GA, Moran CA. So-called sclerosing hemangioma of lung: current concept. Ann Diagn Pathol 2010;14:60-67 https://doi.org/10.1016/j.anndiagpath.2009.07.002
  8. Cheung YC, Ng SH, Chang JW, Tan CF, Huang SF, Yu CT. Histopathological and CT features of pulmonary sclerosing haemangiomas. Clin Radiol 2003;58:630-635 https://doi.org/10.1016/S0009-9260(03)00177-6
  9. Im JG, Kim WH, Han MC, Han YM, Chung JW, Ahn JM, et al. Sclerosing hemangiomas of the lung and interlobar fissures: CT findings. J Comput Assist Tomogr 1994;18:34-38 https://doi.org/10.1097/00004728-199401000-00007
  10. Nakanishi K, Kohzaki S, Fujimoto S, Horita Y, Hayashi K. Pulmonary sclerosing hemangioma: report of a case with emphasis on dynamic MR imaging findings. Radiat Med 1997;15:117-119
  11. Kono R, Fujimoto K, Terasaki H, Muller NL, Kato S, Sadohara J, et al. Dynamic MRI of solitary pulmonary nodules: comparison of enhancement patterns of malignant and benign small peripheral lung lesions. AJR Am J Roentgenol 2007;188:26-36 https://doi.org/10.2214/AJR.05.1446

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