DOI QR코드

DOI QR Code

Cryoablation of a Small Pulmonary Nodule with Pure Ground-Glass Opacity: A Case Report

  • Kim, Kun Yung (Department of Radiology, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Institute for Medical Sciences) ;
  • Jin, Gong Yong (Department of Radiology, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Institute for Medical Sciences) ;
  • Han, Young Min (Department of Radiology, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Institute for Medical Sciences) ;
  • Lee, Yong Chul (Department of Internal Medicine, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Institute for Medical Sciences) ;
  • Jung, Myung Ja (Department of Pathology, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Institute for Medical Sciences)
  • Received : 2014.09.14
  • Accepted : 2015.01.10
  • Published : 2015.06.01

Abstract

Treatments for pure ground-glass nodules (GGNs) include limited resection; however, surgery is not always possible in patients with limited pulmonary functional reserve. In such patients, cryoablation may be a suitable alternative to treat a pure GGN. Here, we report our initial experience with cryoablation of a pure GGN that remained after repeated surgical resection in a patient with multiple GGNs. A 5-mm-sized pure GGN in the left lower lobe was cryoablated successfully without recurrence at the 6-month follow-up.

Keywords

Acknowledgement

Grant : 21세기형 중개연구인력양성사업단

References

  1. Nakajima R, Yokose T, Kakinuma R, Nagai K, Nishiwaki Y, Ochiai A. Localized pure ground-glass opacity on highresolution CT: histologic characteristics. J Comput Assist Tomogr 2002;26:323-329 https://doi.org/10.1097/00004728-200205000-00001
  2. Lim HJ, Ahn S, Lee KS, Han J, Shim YM, Woo S, et al. Persistent pure ground-glass opacity lung nodules ${\geq}$ 10 mm in diameter at CT scan: histopathologic comparisons and prognostic implications. Chest 2013;144:1291-1299 https://doi.org/10.1378/chest.12-2987
  3. Lee HY, Lee KS. Ground-glass opacity nodules: histopathology, imaging evaluation, and clinical implications. J Thorac Imaging 2011;26:106-118 https://doi.org/10.1097/RTI.0b013e3181fbaa64
  4. Park JH, Lee KS, Kim JH, Shim YM, Kim J, Choi YS, et al. Malignant pure pulmonary ground-glass opacity nodules: prognostic implications. Korean J Radiol 2009;10:12-20 https://doi.org/10.3348/kjr.2009.10.1.12
  5. Bang HJ, Littrup PJ, Currier BP, Goodrich DJ, Aoun HD, Klein LC, et al. Percutaneous cryoablation of metastatic lesions from non-small-cell lung carcinoma: initial survival, local control, and cost observations. J Vasc Interv Radiol 2012;23:761-769 https://doi.org/10.1016/j.jvir.2012.02.013
  6. Kim HK, Choi YS, Kim J, Shim YM, Lee KS, Kim K. Management of multiple pure ground-glass opacity lesions in patients with bronchioloalveolar carcinoma. J Thorac Oncol 2010;5:206-210 https://doi.org/10.1097/JTO.0b013e3181c422be
  7. Kuriyama K, Seto M, Kasugai T, Higashiyama M, Kido S, Sawai Y, et al. Ground-glass opacity on thin-section CT: value in differentiating subtypes of adenocarcinoma of the lung. AJR Am J Roentgenol 1999;173:465-469 https://doi.org/10.2214/ajr.173.2.10430155
  8. Rapicetta C, Tenconi S, Voltolini L, Luzzi L, Scala V, Gotti G. Impact of lobectomy for non-small-cell lung cancer on respiratory function in octogenarian patients with mild to moderate chronic obstructive pulmonary disease. Eur J Cardiothorac Surg 2011;39:555-559 https://doi.org/10.1016/j.ejcts.2010.07.043
  9. Hiraki T, Gobara H, Mimura H, Matsui Y, Toyooka S, Kanazawa S. Percutaneous radiofrequency ablation of clinical stage I nonsmall cell lung cancer. J Thorac Cardiovasc Surg 2011;142:24-30 https://doi.org/10.1016/j.jtcvs.2011.02.036
  10. Thanos L, Mylona S, Ptohis N, Tsiouris S, Sotiropoulou E, Pomoni A, et al. Percutaneous radiofrequency thermal ablation in the management of lung tumors: presentation of clinical experience on a series of 35 patients. Diagn Interv Radiol 2009;15:290-296
  11. Zemlyak A, Moore WH, Bilfinger TV. Comparison of survival after sublobar resections and ablative therapies for stage I non-small cell lung cancer. J Am Coll Surg 2010;211:68-72 https://doi.org/10.1016/j.jamcollsurg.2010.03.020
  12. Lee JM, Jin GY, Goldberg SN, Lee YC, Chung GH, Han YM, et al. Percutaneous radiofrequency ablation for inoperable nonsmall cell lung cancer and metastases: preliminary report. Radiology 2004;230:125-134 https://doi.org/10.1148/radiol.2301020934
  13. Pereira PL, Masala S; Cardiovascular and Interventional Radiological Society of Europe (CIRSE). Standards of practice: guidelines for thermal ablation of primary and secondary lung tumors. Cardiovasc Intervent Radiol 2012;35:247-254 https://doi.org/10.1007/s00270-012-0340-1
  14. Jin GY, Han YM, Lee YS, Lee YC. Radiofrequency ablation using a monopolar wet electrode for the treatment of inoperable non-small cell lung cancer: a preliminary report. Korean J Radiol 2008;9:140-147 https://doi.org/10.3348/kjr.2008.9.2.140
  15. Song YS, Park CM, Park SJ, Lee SM, Jeon YK, Goo JM. Volume and mass doubling times of persistent pulmonary subsolid nodules detected in patients without known malignancy. Radiology 2014;273:276-284 https://doi.org/10.1148/radiol.14132324

Cited by

  1. Inducing of Complete Necrosis of Recurred Lung Cancer by Cryoablation: A Case Report vol.75, pp.6, 2015, https://doi.org/10.3348/jksr.2016.75.6.466