Journal of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회지)

Korean Society of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회)
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Re-evaluation of [18F]fluorobenzaldehyde as a prosthetic group

  • Choe, Yearn Seong (Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine,Seoul, Korea and Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University)
  • Received : 2015.09.28
  • Accepted : 2015.12.02
  • Published : 2015.12.30
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Abstract

[$^{18}F$]Fluorobenzaldehyde, which is a versatile radioactive prosthetic group, can undergo reduction, reductive amination, or oxidation to be used for synthesis of diverse radiotracers. This review covers synthesis of [$^{18}F$]fluorobenzaldehyde and its conversion to secondary prosthetic groups, and also highlights its application to the development of radiotracers.

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