The Korean journal of internal medicine

  • 제30권1호
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  • Pages.96-103
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  • 2015
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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DOI QR코드

DOI QR Code

Utilization of the respiratory virus multiplex reverse transcription-polymerase chain reaction test for adult patients at a Korean tertiary care center

  • Ahn, Mi Young (Division of Infectious Diseases, Department of Internal Medicine) ;
  • Choi, Seong-Ho (Division of Infectious Diseases, Department of Internal Medicine) ;
  • Chung, Jin-Won (Division of Infectious Diseases, Department of Internal Medicine) ;
  • Kim, Hye Ryoun (Department of Laboratory Medicine, Chung-Ang University Hospital)
  • 투고 : 2014.03.15
  • 심사 : 2014.04.30
  • 발행 : 2015.01.01
⟨ 이전 논문 다음 논문 ⟩

초록

Background/Aims: Respiratory viruses (RVs) are considered to be important respiratory pathogens in adult patients, and the multiplex reverse transcription-polymerase chain reaction (RT-PCR) test is used frequently in adult patients with respiratory infections. However, clinical data regarding utilization of the multiplex RT-PCR test for RVs are lacking. Methods: We investigated the utilization of the multiplex RT-PCR test for RVs at Chung-Ang University Hospital in Seoul, Korea, between January 2012 and April 2013. Results: During the study period, the multiplex RT-PCR test was performed for 291 adult patients. The test frequency was 4.9% of rapid influenza antigen detection tests and 0.8% of respiratory bacterial culture studies. A turnaround time of < 48 hours was observed in 25.9% of positive tests. Most of the tests were performed for admitted patients (97.9%) with a community-acquired infection (84.2%) during the flu season (82.5%). RVs were detected in 81 of 291 cases (27.8%). The RV positivity rates for community- and hospital-acquired infections did not differ (28.6% vs. 23.9%, p = 0.52). Of 166 patients with pneumonia, 44 (26.5%) had a viral infection. Among the patients with RV-associated pneumonia, an RV other than influenza was detected in 20 patients (45.4%). Conclusions: The multiplex RT-PCR test for RVs was infrequently performed at a tertiary care center, and the test results were often reported late. The test was most often performed for admitted adult patients with community-acquired infections during the flu season. The utilization of multiplex RT-PCR testing for RVs in current clinical practice should be improved.

키워드

참고문헌

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