상급종합병원 근처의 한 지역약국 처방전 분석에 의한 노인 환자의 다약제복용과 약제비용 및 잠재적으로 부적절한 약물사용 관련 위험인자

Risk Factors of Potentially Inappropriate Medications and Cost by Polypharmacy among Elderly Patients of a Community Pharmacy near a Top Tier General Hospital

  • 김아람 (이화여자대학교 임상보건과학대학원) ;
  • 김홍아 (한국의약품안전관리원) ;
  • 이정연 (이화여자대학교 임상보건과학대학원)
  • Kim, Aram (Graduate School of Clinical Health Sciences, Ewha Womans University) ;
  • Kim, Hong Ah (Korea Institute of Drug Safety and Risk Management) ;
  • Rhie, Sandy Jeong (College of Pharmacy and Graduate School of Clinical Health Sciences, Ewha Womans University)
  • 투고 : 2015.07.17
  • 심사 : 2015.08.18
  • 발행 : 2015.09.30

초록

Objective: Polypharmacy is one of the main causes of inappropriate medication use, adverse drug-related events and cost. It aimed to investigate the status of polypharmacy and potentially inappropriate medication (PIM), the factors affecting polypharmacy and cost in elderly outpatients. Method: A pharmacy claim data were retrospectively analyzed with elderly patients prescriptions at a pharmacy located near a top tier general hospital. The numbers of medications per person, prevalence of polypharmacy and PIM according to the 2012 Beers criteria and Korea PIM list, medication cost and the factors affecting polypharmacy were investigated. Results: Forty-six percentages of the elderly outpatients received polypharmacy and over 21% of them had medications listed in Beers or Korean PIM. In multiregressional analysis, we found that age, gender and insurance types were affective factors of polypharmacy. (p < 0.001, 0.047, 0.009, respectively). The cost of polypharmacy with PIM in elderly outpatients was increased with age. Various approaches of interventions would be further required.

키워드

참고문헌

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