Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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A Practical standard Air Flow Generator System to Calibrate and Compare Performance of Two Different Respiratory Air Flow Measurement Modules

호흡기류 계측모듈의 교정과 성능 비교를 위한 실용적인 표준기류 생성 시스템

  • Lee, In-Kwang (Department of Biomedical Engineering, College of Medicine, Chungbuk National University) ;
  • Park, Mi-Jung (Department of Biomedical Engineering, College of Medicine, Chungbuk National University) ;
  • Lee, Sang-Bong (Department of Biomedical Engineering, College of Medicine, Chungbuk National University) ;
  • Kim, Kyoung-Ok (Department of Nursing, Woosong College) ;
  • Cha, Eun-Jong (Department of Biomedical Engineering, College of Medicine, Chungbuk National University) ;
  • Kim, Kyung-Ah (Department of Biomedical Engineering, College of Medicine, Chungbuk National University)
  • 이인광 (충북대학교 의과대학 의공학교실) ;
  • 박미정 (충북대학교 의과대학 의공학교실) ;
  • 이상봉 (충북대학교 의과대학 의공학교실) ;
  • 김경옥 (우송정보대학 간호과) ;
  • 차은종 (충북대학교 의과대학 의공학교실) ;
  • 김경아 (충북대학교 의과대학 의공학교실)
  • Received : 2015.07.31
  • Accepted : 2015.08.20
  • Published : 2015.08.30
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Abstract

A standard air flow generator system was developed to generate air flows of various levels simultaneously applied to two different air flow transducer modules. Axes of two identical standard syringes for spirometer calibration were connected with each other and driven by a servo-motor. Linear displacement transducer was also connected to the syringe axis to accurately acquire the volume change signal. The user can select either sinusoidal or square waveform of volume change and manually input any volume as well as maximal flow rate levels ranging 0~3 l and 0~15 l/s, respectively. Various volume and flow levels were input to operate the system, then the volume signal was acquired followed by numerical differentiation to obtain the air flow signal. The measured volumes and maximal air flow rates were compared with the user input data. The relative errors between the user-input and the measured stroke volumes were all within 0.5%, demonstrating very accurate driving of the system. In case of the maximal flow rate, relatively large error was observed when the syringe was driven very fast within a very short time duration. However, except for these few data, most measured flow rates revealed relative errors of approximately 2%. When the measure and user-input stroke volume and maximal flow rate data were analyzed by linear regression analysis, respectively, the correlation coefficients were satisfactorily higher than 0.99 (p < 0.0001). These results demonstrate that the servo-motor controls the syringes with enough accuracy to generate standard air flows. Therefore, the present system would be very much practical for calibration process as well as performance evaluation and comparison of two different air flow transducer modules.

Keywords

References

  1. M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, A. Coates, R. Crapo, P. Enright, C.P.M. van der Grinten, P. Gustafsson, R. Jensen, D.C. Johnson, N. MacIntyre, R. McKay, D. Navajas, O.F. Pedersen, R. Pellegrino, G. Viegi and J. Wanger, "Standardization of spirometry", Eur Respir J, vol. 26, pp. 319-338, 2005. https://doi.org/10.1183/09031936.05.00034805
  2. A.D. Jr. Renzetti, "Standardization of spirometry", Am Rev Respir Dis, vol. 119, pp. 831-838, 1979.
  3. American Thoracic Society, "Standardization of spirometry: 1987 update", Am Rev Respir Dis, vol. 136, pp. 1285-1298, 1987. https://doi.org/10.1164/ajrccm/136.5.1285
  4. American Thoracic Society, "Standardization of spirometry, 1994 update", Am J Respir Crit Care Med, vol. 152, pp. 1107-1136, 1995. https://doi.org/10.1164/ajrccm.152.3.7663792
  5. P.H. Quanjer, ed. "Standardized lung function testing. Report Working Party Standardization of Lung Function Tests. European Community for Coal and Steel". Bull Eur Physiopathol Respir, vol. 19: Suppl.5, pp. 1-95, 1983.
  6. Official Statement of the European Respiratory Society, "Lung volume and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal", Eur Respir J, vol. 6: Suppl.16, pp. 5-40, 1993. https://doi.org/10.1183/09041950.005s1693
  7. Ministry of Food and Drug Safety, "Performance evaluation guidelines for diagnostic spirometer", 2011.
  8. E. Schenaa, C. Massaronia, P. Saccomandia, S. Cecchinib, "Flow measurement in mechanical ventilation: A review", Medical Engineering & Physics, vol. 37, no. 3, pp. 257-264, 2015. https://doi.org/10.1016/j.medengphy.2015.01.010
  9. E. Russold, T.D. Ambrisko, J.P. Schramel, U. Auer, R. van Den Hoven, Y.P. Moens, "Measurement of tidal volume using respiratory ultrasonic plethysmography in anaesthetized, mechanically ventilated horses", Veterinary Anaesthesia and Analgesia, vol. 40, no. 1, pp. 48-54, 2013. https://doi.org/10.1111/j.1467-2995.2012.00751.x
  10. A.A. Mohammad, V.R. Nafisi1, F. Farhani, "Extrapolation of calibration curve of hot-wire spirometer using a novel neural network based approach", Journal of Medical Signals & Sensors, vol. 2, no. 4, pp. 185-191, 2012.
  11. K.A. Kim, T.S. Lee, E.J. Cha, "Unequal distance sampling technique to design velocity-type respiratory air flow transducer", J. Biomed. Eng. Res., vol. 25, no. 5, pp. 351-359, 2004.
  12. K.A. Kim, T.S. Lee, E.J. Cha, "Design Criteria to Miniaturize the Single Use Functional Respiratory Air Flow Tube", J. Biomed. Eng. Res., vol. 26, no. 3, pp. 163-169, 2005.
  13. W.J. Yoo, J.Y. Baek, D.H. Cho, K.W. Jang, J.K. Seo, J.Y. Heo, B.S. Lee, Y.H. Cho, B.G. Park, J.H. Moon, "Development of a respiration sensor using plastic optical fiber", J. Biomed. Eng. Res., vol. 30, no. 6, pp. 489-494, 2009.
  14. K.A. Kim, I.K. Lee, J.O. Park, S.O, Lee, E.Y. Shin, Y.K Kim, K.C. Kim, E.J. Cha, "Respiratory air flow transducer based on air turbulence", J. Biomed. Eng. Res., vol. 30, no. 5, pp. 393-400, 2009.
  15. D.W. Kim, D.S. Yeon, S.C. Kim, "Development of respiratory monitoring system by inductive plethysmography", J. Biomed. Eng. Res., vol. 16, no. 3, pp. 353-358, 1995.
  16. Chungbuk National Univ. Industry-University Cooperation Foundation, "Calibration and performance verification device for diagnostic spirometer", Korea, Patent No. 10-1533887, 2015.
  17. B.G. Jeon, Y.G. Kang, K.A. Kim, T.S. Lee, E.J. Cha, "Volume accuracy of the servo-motor driven standard air flow generator system", Journal of Korea Intellectual Patent Society, vol. 7, no. 1, pp. 79-82, 2005.