The korean journal of orthodontics (대한치과교정학회지)

The Korean Association Of Orthodontists (대한치과교정학회)
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Aspartate aminotransferase activity in the pulp of teeth treated for 6 months with fixed orthodontic appliances

  • Veberiene, Rita (Clinic of Dental and Oral Pathology, Faculty of Odontology, Lithuanian University of Health Sciences) ;
  • Latkauskiene, Dalia (Kaunas Centre of Orthodontics) ;
  • Racinskaite, Vilma (Clinic of Dental and Oral Pathology, Faculty of Odontology, Lithuanian University of Health Sciences) ;
  • Skucaite, Neringa (Clinic of Dental and Oral Pathology, Faculty of Odontology, Lithuanian University of Health Sciences) ;
  • Machiulskiene, Vita (Clinic of Dental and Oral Pathology, Faculty of Odontology, Lithuanian University of Health Sciences)
  • Received : 2014.12.17
  • Accepted : 2015.05.01
  • Published : 2015.09.25
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Abstract

Objective: To measure aspartate aminotransferase (AST) activity in the pulp of teeth treated with fixed appliances for 6 months, and compare it with AST activity measured in untreated teeth. Methods: The study sample consisted of 16 healthy subjects (mean age $25.7{\pm}4.3$ years) who required the extraction of maxillary premolars for orthodontic reasons. Of these, 6 individuals had a total of 11 sound teeth extracted without any orthodontic treatment (the control group), and 10 individuals had a total of 20 sound teeth extracted after 6 months of orthodontic alignment (the experimental group). Dental pulp samples were extracted from all control and experimental teeth, and the AST activity exhibited by these samples was determined spectrophotometrically at $20^{\circ}C$. Results: Mean AST values were $25.29{\times}10^{-5}U/mg$ (standard deviation [SD] 9.95) in the control group and $27.54{\times}10^{-5}U/mg$ (SD 31.81) in the experimental group. The difference between these means was not statistically significantly (p = 0.778), and the distribution of the AST values was also similar in both groups. Conclusions: No statistically significant increase in AST activity in the pulp of mechanically loaded teeth was detected after 6 months of orthodontic alignment, as compared to that of teeth extracted from individuals who had not undergone orthodontic treatment. This suggests that time-related regenerative processes occur in the dental pulp.

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References

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