Anti-Cancer Natural Products Inducing Cross-talk between Apoptosis and Autophagy Mutual Proteins to Regulate Cancer Cell Death: Design of Future Green Anticancer Therapies

DOI QR Code

Vijayarathna, Soundararajan (Institute for Research in Molecular Medicine, Universiti Sains Malaysia) ;
Jothy, Subramanion L (Institute for Research in Molecular Medicine, Universiti Sains Malaysia) ;
Chen, Yeng (Dental Research & Training Unit, and Oral Cancer Research and Coordinating Centre, Faculty of Dentistry, University of Malaya) ;
Kanwar, Jagat R (Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research, School of Medicine, Faculty of Health, Institute for Frontier Materials, Deakin University) ;
Sasidharan, Sreenivasan (Institute for Research in Molecular Medicine, Universiti Sains Malaysia)

Delmas D, Solary E, Latruffe N (2011). Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagyand mitotic catastrophe. Curr Med Chem, 18, 1100-21. https://doi.org/10.2174/092986711795029708
Du P, Cao H, Wu HR, et al (2013). Blocking Bcl-2 leads to autophagy activation and cell death of the HEPG2 liver cancer cell line. Asian Pac J Cancer Prev, 14, 5849-54. https://doi.org/10.7314/APJCP.2013.14.10.5849
Hematulin A, Ingkaninan K, Limpeanchob N, Sagan D (2014). Ethanolic extract from Derris scandens Benth mediates radiosensitzation via two distinct modesof cell death in human colon cancer HT-29 cells. Asian Pac J Cancer Prev, 15, 1871-7. https://doi.org/10.7314/APJCP.2014.15.4.1871
Safarzadeh E, Sandoghchian Shotorbani S, Baradaran B (2014) Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull, 4, 421-7.
Wang N, Feng Y (2015). Elaborating the role of natural productsinduced autophagy in cancer treatment: achievements and artifacts in the state of the art. Biomed Res Int, 2015, 934207.
Xu M-Y, Lee DH, Joo EJ, Son KH, Kim YS (2013). Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. Food Chem Toxicol, 59, 703-8. https://doi.org/10.1016/j.fct.2013.06.059

Amarogentin Induces Apoptosis of Liver Cancer Cells via Upregulation of p53 and Downregulation of Human Telomerase Reverse Transcriptase in Mice vol.16, pp.5, 2017, https://doi.org/10.1177/1533034616657976
Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure vol.14, pp.8, 2016, https://doi.org/10.3390/md14080154
Inhibition of breast cancer cell growth by methyl pyropheophenylchlorin photodynamic therapy is mediated though endoplasmic reticulum stress-induced autophagy in vitro and vivo vol.7, pp.5, 2018, https://doi.org/10.1002/cam4.1418