References
- Carter SK, Comis RL (1975). The integration of chemotherapy into a combined modality approach for cancer treatment. VI. Pancreatic adenocarcinoma. Cancer Treat Rev, 2, 193-214. https://doi.org/10.1016/S0305-7372(75)80003-X
- Bayoglu IV, Varol U, Yildiz I, et al (2014). Second-line capecitabine and oxaliplatin combination for gemcitabineresistant advanced pancreatic cancer. Asian Pac J Cancer Prev, 15, 7119-23. https://doi.org/10.7314/APJCP.2014.15.17.7119
- Berlin JD, Catalano P, Thomas JP, et al (2002). Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: eastern cooperative oncology group trial E2297. J Clin Oncol, 20, 3270-5. https://doi.org/10.1200/JCO.2002.11.149
- Bernhard J, Dietrich D, Scheithauer W, et al (2008). Clinical benefit and quality of life in patients with advanced pancreatic cancer receiving gemcitabine plus capecitabine versus gemcitabine alone: a randomized multicenter phase III clinical trial--SAKK 44/00-CECOG/PAN. 1. 3. 001. J Clin Oncol, 26, 3695-701. https://doi.org/10.1200/JCO.2007.15.6240
- Bond-Smith G, Banga N, Hammond TM, et al (2012). Pancreatic adenocarcinoma. Bmj, 344, e2476. https://doi.org/10.1136/bmj.e2476
- Bria E, Milella M, Gelibter A, et al (2007). Gemcitabine-based combinations for inoperable pancreatic cancer: have we made real progress? A meta-analysis of 20 phase 3 trials. Cancer, 110, 525-33. https://doi.org/10.1002/cncr.22809
- Burris HA, 3rd, Moore MJ, Andersen J, et al (1997). Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol, 15, 2403-13.
- Cartwright TH, Cohn A, Varkey JA, et al (2002). Phase II study of oral capecitabine in patients with advanced or metastatic pancreatic cancer. J Clin Oncol, 20, 160-4. https://doi.org/10.1200/JCO.20.1.160
- Choi JG, Seo JH, Oh SC, et al (2012). A Phase II Trial of gemcitabine plus capecitabine for patients with advanced pancreatic cancer. Cancer Res Treat, 44, 127-32. https://doi.org/10.4143/crt.2012.44.2.127
- Ciliberto D, Botta C, Correale P, et al (2013). Role of gemcitabinebased combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials. Eur J Cancer, 49, 593-603. https://doi.org/10.1016/j.ejca.2012.08.019
- Cullinan SA, Moertel CG, Fleming TR, et al (1985). A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin. Jama, 253, 2061-7. https://doi.org/10.1001/jama.1985.03350380077025
- Cunningham D, Chau I, Stocken DD, et al (2009). Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer. J Clin Oncol, 27, 5513-8. https://doi.org/10.1200/JCO.2009.24.2446
- Di Costanzo F, Carlini P, Doni L, et al (2005). Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC). Br J Cancer, 93, 185-9. https://doi.org/10.1038/sj.bjc.6602640
- Ducreux M, Rougier P, Pignon JP, et al (2002). A randomised trial comparing 5-FU with 5-FU plus cisplatin in advanced pancreatic carcinoma. Ann Oncol, 13, 1185-91. https://doi.org/10.1093/annonc/mdf197
- el-Kamar FG, Grossbard ML, Kozuch PS (2003). Metastatic pancreatic cancer: emerging strategies in chemotherapy and palliative care. Oncologist, 8, 18-34.
- Haller DG (2003). Chemotherapy for advanced pancreatic cancer. Int J Radiat Oncol Biol Phys, 56, 16-23. https://doi.org/10.1016/S0360-3016(03)00448-6
- Herrmann R, Bodoky G, Ruhstaller T, et al (2007). Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer: a randomized, multicenter, phase III trial of the swiss group for clinical cancer research and the central european cooperative oncology group. J Clin Oncol, 25, 2212-7. https://doi.org/10.1200/JCO.2006.09.0886
- Higgins JP, Thompson SG (2002). Quantifying heterogeneity in a meta-analysis. Stat Med, 21, 1539-58. https://doi.org/10.1002/sim.1186
- Higgins JP, Thompson SG, Deeks JJ, et al (2003). Measuring inconsistency in meta-analyses. Bmj, 327, 557-60. https://doi.org/10.1136/bmj.327.7414.557
- Hoff PM, Saad ED, Ajani JA, et al (2003). Phase I study with pharmacokinetics of S-1 on an oral daily schedule for 28 days in patients with solid tumors. Clin Cancer Res, 9, 134-42.
- Huai P, Xun H, Reilly KH, et al (2013). Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. Hypertension, 62, 1021-6. https://doi.org/10.1161/HYPERTENSIONAHA.113.01965
- Jemal A, Siegel R, Ward E, et al (2008). Cancer statistics, 2008. CA Cancer J Clin, 58, 71-96. https://doi.org/10.3322/CA.2007.0010
- Kim MK, Lee KH, Jang BI, et al (2009). S-1 and gemcitabine as an outpatient-based regimen in patients with advanced or metastatic pancreatic cancer. Jpn J Clin Oncol, 39, 49-53.
- Lee GW, Kim HJ, Ju JH, et al (2009). Phase II trial of S-1 in combination with gemcitabine for chemo-naive patients with locally advanced or metastatic pancreatic cancer. Cancer Chemother Pharmacol, 64, 707-13. https://doi.org/10.1007/s00280-008-0918-0
- Li Q, Yan H, Liu W, et al (2014). Efficacy and safety of gemcitabine-fluorouracil combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomized controlled trials. PLoS One, 9, 104346. https://doi.org/10.1371/journal.pone.0104346
- Miwa M, Ura M, Nishida M, et al (1998). Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer, 34, 1274-81. https://doi.org/10.1016/S0959-8049(98)00058-6
- Morizane C, Okusaka T, Furuse J, et al (2009). A phase II study of S-1 in gemcitabine-refractory metastatic pancreatic cancer. Cancer Chemother Pharmacol, 63, 313-9. https://doi.org/10.1007/s00280-008-0741-7
- Nakai Y, Isayama H, Sasaki T, et al (2012). A multicentre randomised phase II trial of gemcitabine alone vs gemcitabine and S-1 combination therapy in advanced pancreatic cancer: GEMSAP study. Br J Cancer, 106, 1934-9. https://doi.org/10.1038/bjc.2012.183
- Nakamura K, Yamaguchi T, Ishihara T, et al (2006). Phase II trial of oral S-1 combined with gemcitabine in metastatic pancreatic cancer. Br J Cancer, 94, 1575-9.
- Oh DY, Cha Y, Choi IS, et al (2010). A multicenter phase II study of gemcitabine and S-1 combination chemotherapy in patients with unresectable pancreatic cancer. Cancer Chemother Pharmacol, 65, 527-36. https://doi.org/10.1007/s00280-009-1059-9
- Ohkawa S. (2004). Randomized controlled trial of gemcitabine in com-bination with UFT versusgemcitabine alone in patients withadvanced pancreatic cancer. J Clin Oncol, 22, 4131.
- Ozaka M, Matsumura Y, Ishii H, et al (2012). Randomized phase II study of gemcitabine and S-1 combination versus gemcitabine alone in the treatment of unresectable advanced pancreatic cancer (Japan clinical cancer research organization PC-01 study). Cancer Chemother Pharmacol, 69, 1197-204. https://doi.org/10.1007/s00280-012-1822-1
- Riess H, Helm A, Niedergethmann M, et al (2005). A randomised, prospective, multicenter, phase III trial of gemcitabine, 5-fluorouracil (5-FU), folinic acid vs. gemcitabine alone in patientswithadvanced pancreatic cancer. J Clin Oncol, 23
- Rougier P, Zarba JJ, Ducreux M, et al (1993). Phase II study of cisplatin and 120-hour continuous infusion of 5-fluorouracil in patients with advanced pancreatic adenocarcinoma. Ann Oncol, 4, 333-6.
- Satoh T, Sakata Y (2012). S-1 for the treatment of gastrointestinal cancer. Expert Opin Pharmacother, 13, 1943-59. https://doi.org/10.1517/14656566.2012.709234
- Scheithauer W, Schull B, Ulrich-Pur H, et al (2003). Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial. Ann Oncol, 14, 97-104. https://doi.org/10.1093/annonc/mdg029
- Shi S, Yao W, Xu J, et al (2012). Combinational therapy: new hope for pancreatic cancer? Cancer Lett, 317, 127-35. https://doi.org/10.1016/j.canlet.2011.11.029
- Shirasaka T, Nakano K, Takechi T, et al (1996). Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2, 4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res, 56, 2602-6.
- Strimpakos A, Saif MW, Syrigos KN (2008). Pancreatic cancer: from molecular pathogenesis to targeted therapy. Cancer Metastasis Rev, 27, 495-522. https://doi.org/10.1007/s10555-008-9134-y
- Sudo K, Ishihara T, Hirata N, et al (2014). Randomized controlled study of gemcitabine plus S-1 combination chemotherapy versus gemcitabine for unresectable pancreatic cancer. Cancer Chemother Pharmacol, 73, 389-96. https://doi.org/10.1007/s00280-013-2368-6
- Tong GX, Geng QQ, Chai J, et al (2014). Association between pancreatitis and subsequent risk of pancreatic cancer: a systematic review of epidemiological studies. Asian Pac J Cancer Prev, 15, 5029-34. https://doi.org/10.7314/APJCP.2014.15.12.5029
- Ueno H, Ioka T, Ikeda M, et al (2013). Randomized phase III study of gemcitabine plus S-1, S-1 alone, or gemcitabine alone in patients with locally advanced and metastatic pancreatic cancer in Japan and Taiwan: GEST study. J Clin Oncol, 31, 1640-8. https://doi.org/10.1200/JCO.2012.43.3680
- Ueno H, Okusaka T, Ikeda M, et al (2005a). A phase I study of combination chemotherapy with gemcitabine and oral S-1 for advanced pancreatic cancer. Oncol, 69, 421-7. https://doi.org/10.1159/000089997
- Ueno H, Okusaka T, Ikeda M, et al (2005b). An early phase II study of S-1 in patients with metastatic pancreatic cancer. Oncol, 68, 171-8. https://doi.org/10.1159/000086771
- van Groeningen CJ, Peters GJ, Schornagel JH, et al (2000). Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors. J Clin Oncol, 18, 2772-9.
- Ying JE, Zhu LM, Liu BX (2012). Developments in metastatic pancreatic cancer: is gemcitabine still the standard? World J Gastroenterol, 18, 736-45. https://doi.org/10.3748/wjg.v18.i8.736
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