Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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An Audit of 204 Histopathology Reports Over Three Years of Carcinoma of Cervix: Experience from a Tertiary Referral Centre

  • Published : 2015.09.02
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Abstract

Background: The aim was to see compliance to minimum data set information in carcinoma cervix histopathology reports from a team of 13 pathologists; and also to analyse the distribution of parameters like tumor size, grade, depth of cervical stromal invasion, lymph node yield and pTNM stage. Materials and Methods: All pathology reports of radical hysterectomy for carcinoma cervix operated in house within a three year duration (2010-2012), (n=204) were retrieved from medical records and analyzed for the above parameters. Results: In 2010- 59 cases, in 2011- 67 cases and in 2012- 78 cases of carcinoma cervix underwent operations in our hospital. The median age was 50.5 years and the maximum T diameter was 2.8 cms in the reports of three years. Squamous carcinoma was the commonest subtype amongst all the tumors. It was noted that 60.8% of cases had cervical stromal involvement more than half the thickness of the cervical stroma. Parametrial involvement was seen in 4.82% of cases. pTNM Staging was not mentioned in 65.06% of the cases. The mean bilateral pelvic lymph node yield count in our study was 16.6 inclusive of all the three years. Conclusions: Compliance with provision of a minimum dataset in our team of 13 pathologists was generally good. Lymph node yield in our hands is reasonable, but constant striving for greater numbers should be made. pTNM staging should be more meticulously documented. Use of proformas /checklists is recommended.

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References

  1. Aoki Y SM, Watanabe M, et al (2000). High-risk group in node-positive patients with stage IB, IIA, and IIB cervical carcinoma after radical hysterectomy and postoperative pelvic irradiation. Gynecol Oncol, 77, 305-9. https://doi.org/10.1006/gyno.2000.5788
  2. Chatchotikawong U,Ruengkhachorn I, Leelaphatanadit C (2014). Residual disease following conization of women with stage IA-IB1 cervical carcinoma in a high incidence region. Asian Pac J Cancer Prev, 15, 7383-87. https://doi.org/10.7314/APJCP.2014.15.17.7383
  3. Delgado G BB, Zaino R, Sevin BU, Creasman WT, Major F (1990). Prospective surgical pathological study of diseasefree interval in patients with stage IB squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study. Gynecol Oncol, 38, 352-7. https://doi.org/10.1016/0090-8258(90)90072-S
  4. Horn LC EJ, Hockel M, et al (2005). [Recommendations for the handling and oncologic pathology report of lymph node specimens submitted for evaluation of metastatic disease in gynecologic malignancies]. Pathologe, 26, 266-72. https://doi.org/10.1007/s00292-005-0764-3
  5. Kamura T ST, Kaku T et al (1999). Histopathological factors influencing pelvic lymph node metastases in two or more sites in patients with cervical carcinoma undergoing radical hysterectomy. Acta Obstet Gynecol Scand, 78, 452-7. https://doi.org/10.1080/j.1600-0412.1999.780520.x
  6. Mamoon N, Hassan U, Mushtaq S, et al (2010). Histopathology of breast carcinoma-an audit of 50 Reports in Rawalpindi, Pakistan. Asian Pac J Cancer Prev, 11, 169-72.
  7. Nambiar A, Vivek N, Bindu M, et al (2010). Completeness of low anterior resection pathology report: A hospital-based audit with recommendations on improving reporting. Indian J Cancer, 47, 156-9. https://doi.org/10.4103/0019-509X.63010
  8. Pieterse Q, Kenter G, Gaarenstroom K, et al (2007). The number of pelvic lymph nodes in the quality control and prognosis of radical hysterectomy for the treatment of cervical cancer. Eur J Surg Oncol, 33, 216-21. https://doi.org/10.1016/j.ejso.2006.09.037
  9. Prapaporn S KC, Surapan K (2012). Pelvic node removal and disease-free survival in cervical cancer patients treated with radical hysterectomy and pelvic lymphadenectomy. Int J Gynecol Obstet, 116, 43-6. https://doi.org/10.1016/j.ijgo.2011.08.001
  10. Randall ME FP, Toita T et al (2013) Principles and Practice of gynecologic oncology, Philadelphia, Lipincott Williams and Wilins.
  11. Samlal RA vdVJ, Ten Kate FJ, Schilthuis MS, Hart AA LF (1997). Surgical pathologic factors that predict recurrence in stage IB and IIA cervical carcinoma patients with negative pelvic lymph nodes. Cancer, 80, 1234-40. https://doi.org/10.1002/(SICI)1097-0142(19971001)80:7<1234::AID-CNCR6>3.0.CO;2-K
  12. Sethasathien S, Charoenkwan K, Settakorn J, Srisomboon J. (2014). Predicting factors for positive vaginal surgical margin following radical hysterectomy for stage IB1 carcinoma of the cervix. Asian Pac J Cancer Prev, 15, 2211-15. https://doi.org/10.7314/APJCP.2014.15.5.2211
  13. Sykes P AD, Cohen C, Scurry J, Yeo D (2003). Does the density of lymphatic vascular space invasion affect the prognosis of stage Ib and IIA node negative carcinoma of the cervix? Int J Gynecol Cancer, 13, 313-6. https://doi.org/10.1046/j.1525-1438.2003.13024.x
  14. Takeda N SN, Takeda M et al (2002). Multivariate analysis of histopathologic prognostic factors for invasive cervical cancer treated with radical hysterectomy and systematic retroperitoneal lymphadenectomy. Acta Obstet Gynecol Scand, 81, 1144-51. https://doi.org/10.1034/j.1600-0412.2002.811208.x
  15. Verleye L VI, Reed N, Ottevanger PB (2009). Quality assurance for radical hysterectomy for cervical cancer: the view of the European organization for research and treatment of cancer?gynecological cancer group (EORTC-GCG). Ann Oncol, 20, 1631-8. https://doi.org/10.1093/annonc/mdp196
  16. Zreik TG, Chambers JT, Chambers SK (1996). Parametrial involvement, regardless of nodal status: a poor prognostic factor for cervical cancer. Obstet Gynecol, 87, 741-6. https://doi.org/10.1016/0029-7844(96)00026-9