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Numerical Study on Blood Flow Dynamics and Wall Mechanics in a Compliant Carotid Bifurcation Model

혈관 유연성을 고려한 경동맥 분기부 모델 혈류역학 해석

  • Published : 2015.08.31

Abstract

Blood flow simulations in an realistic carotid bifurcation model with considering wall compliance were carried out to investigate the effect of wall elasticity on the wall shear stress and wall solid stress. Canonical waveforms of flow rates and pressure in carotid arteries were imposed for boundary conditions. Compared to a rigid wall model, we found an increased recirculation region at the carotid bulb and an overall reduction of wall shear stress in a compliant model. Additionally, there was appreciable change of flow rate and pressure wave in longitudinal direction. Both solid and wall shear stress concentration occur at the bifurcation apex.

Keywords

References

  1. Salzar, R.S., Thubrikar, M. J. and Eppink, R. T., 1995, "Pressure-induced Mechanical Stress in the Carotid Artery Bifurcation: A Possible Correlation to Atherosclerosis," J. Biomech. Vol.28, pp.1333-1340. https://doi.org/10.1016/0021-9290(95)00005-3
  2. Glagov, S., Rowley D. A. and Kohut R. I., 1961, "Atherosclerosis of Human Aorta and Its Coronary and Renal Arteries. A Consideration of Some Hemodynamic Factors Which May Be Related to the Marked Differences in Atherosclerotic Involvement of the Coronary and Renal Arteries," Arch. Pathol. Vol.72, pp.82-95.
  3. Zhao, S. Z., Ariff, B., Long, Q., Hughes, A. D., Thom, S. A., Stanton, A. V. and Xu, X. Y., 2002, "Inter-individual Variation in Wall Shear Stress and Mechanical Stress Distribution at the Carotid Artery Bifurcation of Healthy Humans," J. Biomech. Vol.35, pp.1367-1377 https://doi.org/10.1016/S0021-9290(02)00185-9
  4. Perktold, K. and Rappitsch, G., 1995, "Computer Simulation of Local Blood Flow and Vessel Mechanics in a Compliant Carotid Artery Bifurcation Model," J. Biomech. Vol.28, pp.845-856. https://doi.org/10.1016/0021-9290(95)95273-8
  5. Yang, C., Canton, G., Yuan, C., Ferguson, M., Hatsukami, T. S. and Tang, D., "Advanced Human Carotid Plaque Progression Correlates Positively with Flow Shear Stress using Follow-up Scan Data: An in vivo MRI Multi-patient 3D FSI Study," J. Biomech. Vol.43, pp.2530-2538.
  6. Zhao, S. Z., Xu, X. Y., Hughes, A. D., Thom, S. A., Stanton, A. V., Ariff, B. and Long, Q., 2000, "Blood Flow and Vessel Mechanics in a Physiologically Realistic Model of a Human Carotid Arterial Bifurcation," J. Biomech., Vol.33, pp.975-984. https://doi.org/10.1016/S0021-9290(00)00043-9
  7. Ford, M. D., Alperin, N., Lee, S. H., Holdsworth, D. W. and Steinman, D. A., 2005, "Characterization of Volumetric Flow Rate Waveforms in the Normal Internal Carotid and Vertebral Arteries," Physiol. Meas. Vol.26, pp.477-488. https://doi.org/10.1088/0967-3334/26/4/013
  8. Marshall, I., Papathanasopoulou, P. and Wartolowska, K., 2004, "Carotid Flow Rates and Flow Division at the Bifurcation in Healthy Volunteers," Physiol. Meas. Vol.25, pp.691-697. https://doi.org/10.1088/0967-3334/25/3/009

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