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Ablation Characteristics of Bovine Liver According to Cool-Tip Temperature of RFA Equipment

고주파 열치료 장비의 Cool-Tip 온도에 따른 소간의 소작 특성

  • 최영재 (서울대학교병원 영상의학과) ;
  • 김정구 (한서대학교 방사선학과)
  • Received : 2015.03.31
  • Accepted : 2015.06.09
  • Published : 2015.06.30

Abstract

This study confirmed the correlation between the change of the cooling water in internal cooling system and the size of the ablation site of bovine liver in RF heat treatment equipment. The bovine liver was resection with $4{\times}4{\times}4cm^3$ in 2cm cool-tip and with $6{\times}6{\times}6cm^3$ in 3cm cool-tip for the experiments. Area and perimeter of the ablation site for bovine liver were measured by Freehand techniques of MRI. It showed area and perimeter decreased during cool-tip temperature rises 6 and 12 minutes ablation using a 2cm and 3cm cool-tip. The correlation of cool-tip temperature and area and perimeter was statistically significant the result are shown(p=.000). The measurements of area and perimeter were more accurate with MRI in actual measurements and MRI for ablation range. The statistical results using Paired sample T-test was also significant(p=.038). The ablation range of bovine liver decreased according as cooling water temperature increases in RF heat treatment equipment for reason of carbonization occurred due to does not accurately pass the RF energy. Therefore, it is considered the effect of RF heat treatment would be increased if the temperature of the cooling water consistently maintain the low temperature in order to reduce the generation of carbide at RF heat treatment and RF energy is delivered accurately.

본 연구는 고주파 열치료 시 내부냉각방식 cool-tip의 냉각수 온도에 따른 소작 특성을 확인하기 위하여 소간을 이용하여 냉각수 온도변화에 따른 소간의 소작 특성의 변화를 통해 냉각수 온도변화와 소작 특성의 상관관계를 확인하고자 하였다. 실험에 사용된 소간은 2 cm cool-tip 사용 시 $4{\times}4{\times}4cm^3$, 3 cm인 cool-tip 사용 시에는 $6{\times}6{\times}6cm^3$로 소간을 절제하였으며, 소작된 소간은 MRI를 이용하여 영상검사를 실시하였으며, Freehand 기법으로 소작된 부위의 면적과 둘레를 측정하였다. 2 cm, 3 cm cool-tip을 사용하여 6분, 12분 소작 시 cool-tip 온도가 상승함에 따라 면적과 둘레는 감소함을 나타냈으며, cool-tip 온도와 면적 및 둘레의 상관관계는 통계학적으로 유의한 결과를 나타내었다(p=.000). 소작 범위에 대한 실제 측정과 MRI을 이용한 측정을 비교한 결과 MRI를 이용한 면적과 둘레 측정이 더 정확한 것을 확인하였으며, 대응표본 T-검정을 이용한 통계적 결과 또한 유의하였다(p=.038). 고주파 열치료 장비의 cool-tip 냉각수 온도가 증가함에 따라 소간의 소작 범위가 감소한 원인은 고주파 열치료 장비의 에너지가 정확히 전달되지 못하고 탄화가 발생하기 때문이다. 따라서 고주파 열치료에서 탄화의 발생을 줄이고, 고주파 에너지가 정확히 전달되어 치료 효과를 높이기 위해서는 냉각수의 온도를 낮은 온도로 일정하게 유지하여 사용하여야 고주파 열치료의 효과가 증대될 것이라 사료된다.

Keywords

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