DOI QR코드

DOI QR Code

A Giant Keratoacanthoma Treated with Surgical Excision

  • Park, Hyochun (Department of Plastic and Reconstructive Surgery, Daegu Fatima Hospital) ;
  • Park, Hannara (Department of Plastic and Reconstructive Surgery, Daegu Fatima Hospital) ;
  • Kim, Hoonnam (Department of Plastic and Reconstructive Surgery, Daegu Fatima Hospital) ;
  • Yeo, Hyeonjung (Department of Plastic and Reconstructive Surgery, Daegu Fatima Hospital)
  • Received : 2015.02.14
  • Accepted : 2015.08.04
  • Published : 2015.08.09

Abstract

A keratoacanthoma is a rapidly growing cutaneous tumor that spontaneously involutes in most instances. A giant keratoacanthoma is a rare variant and are characterized by lesions larger than 20 mm in diameter. We report a 56-year-old man with a rapidly growing tumor of the right cheek, which was diagnosed as keratoacanthoma. The mass was excised completely under general anesthesia, followed by Limberg flap for reconstruction. Intraoperative frozen section histology suggested the lesion to be a well-differentiated squamous cell carcinoma, whereas final histopathology was consistent with keratoacanthoma. We herein report the first case of a giant keratoacanthoma treated with surgical excision in Korea and discuss the clinical and histopathological features of keratoacanthoma, with a review of the literature.

Keywords

References

  1. Garcia-Zuazaga J, Ke M, Lee P. Giant keratoacanthoma of the upper extremity treated with mohs micrographic surgery: a case report and review of current treatment modalities. J Clin Aesthet Dermatol 2009;2:22-5.
  2. de Visscher JG, van der Wal KG, Blanken R, Willemse F. Treatment of giant keratoacanthoma of the skin of the lower lip with intralesional methotrexate: a case report. J Oral Maxillofac Surg 2002;60:93-5. https://doi.org/10.1053/joms.2002.29083
  3. Rani N, Kumar P, Patil JD, Choudhary SS. Keratoacanthoma centrifugam marginatum: an atypical presentation. J Postgrad Med 2013;59:58-60. https://doi.org/10.4103/0022-3859.109500
  4. Kim CW, Kim CH, Lim YH, Nam ES. A case of keratoacanthomalike squamous cell carcinoma of the auricle. Korean J Otolaryngol-Head Neck Surg 2006;49:225-7.
  5. Rho WS, Kim HB. Keratoacanthoma of the eye lid. J Korean Ophthalmol Soc 1986;27:1085-9.
  6. Shin SJ, Park DH. Clinical experience of cutaneous squamous cell carcinoma arising in keratoacanthoma. J Korean Soc Plast Reconstr Surg 2006;33:506-9.
  7. Hong HS, Ahn H, Eom JW. A case of giant keratoacanthoma of the lower lip treated with intralesional methotrexate. Korean J Otolaryngol-Head Neck Surg 1997;40:1858-62.
  8. Schwartz RA. Keratoacanthoma: a clinico-pathologic enigma. Dermatol Surg 2004;30:326-33.
  9. Hopkins K, Paul S, Weedon D, Rosendahl C. Use of double-bladed biopsy in distinguishing keratoacanthoma from squamous cell carcinoma: a case report. Dermatol Pract Concept 2013;3:43-6.
  10. Pyne JH, Windrum G, Sapkota D, Wong JC. Keratoacanthoma versus invasive squamous cell carcinoma: a comparison of dermatoscopic vascular features in 510 cases. Dermatol Pract Concept 2014;4:37-41.
  11. Godbolt AM, Sullivan JJ, Weedon D. Keratoacanthoma with perineural invasion: a report of 40 cases. Australas J Dermatol 2001;42:168-71. https://doi.org/10.1046/j.1440-0960.2001.00508.x
  12. Tschandl P, Rosendahl C, Williamson R, Weedon D. A keratoacanthoma with venous invasion. Dermatol Pract Concept 2012;2:204a03.
  13. Ko CJ. Keratoacanthoma: facts and controversies. Clin Dermatol 2010;28:254-61. https://doi.org/10.1016/j.clindermatol.2009.06.010
  14. Spieth K, Gille J, Kaufmann R. Intralesional methotrexate as effective treatment in solitary giant keratoacanthoma of the lower lip. Dermatology 2000;200:317-9. https://doi.org/10.1159/000018395
  15. Parvanescu H, Mogoanta L, Foarfa C, Ciurea M, Georgescu A, Nicolae C. Giant keratoacanthoma of the hand. Rom J Morphol Embryol 2005;46:235-8.