Journal of Digestive Cancer Research

Korean Society of Gastrointestinal Cancer Research (대한소화기암연구학회)
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Stroke-like Manifestation in a Patient with Leptomeningeal Metastasis of Pancreatic Cancer

급성뇌졸중 양상으로 발현된 췌장암의 연수막 전이

  • Boo Suk Na (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Soo Jin Song (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Jong Min Song (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Ho Geol Woo (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Young Nam Kwon (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Dokyung Lee (Department of Neurology, College of Medicine, Kyung Hee University) ;
  • Tae-Beom Ahn (Department of Neurology, College of Medicine, Kyung Hee University)
  • 나부석 (경희대학교 의과대학 신경과학교실) ;
  • 송수진 (경희대학교 의과대학 신경과학교실) ;
  • 송종민 (경희대학교 의과대학 신경과학교실) ;
  • 우호걸 (경희대학교 의과대학 신경과학교실) ;
  • 권영남 (경희대학교 의과대학 신경과학교실) ;
  • 이도경 (경희대학교 의과대학 신경과학교실) ;
  • 안태범 (경희대학교 의과대학 신경과학교실)
  • Received : 2015.09.04
  • Accepted : 2015.12.18
  • Published : 2015.12.31
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Abstract

Pancreatic cancer is commonly presented with distant metastasis. However metastasis to central nervous system (CNS) of pancreatic cancer was rarely reported. 79-years-old man was hospitalized with sudden onset right arm dysesthesia and weakness. In brain magnetic resonance imaging, multifocal high signal intensity lesions in cerebral and cerebellar cortices were observed. Leptomeningeal and parenchymal enhanced lesions were also noted in contrast-enhanced T1 images suggesting a metastasis from the pancreatic cancer. Stroke like manifestation of CNS metastasis of pancreatic cancer is extremely rare. Careful history taking and evaluation should be performed to find the origin of the sudden neurologic deficit.

본 증례는 전이성 췌장암에서 연수막전이로 발현된 국내 첫 사례이다. 또한 급성뇌졸중 양상이 첫 증상으로 발현된 경우도 이전에 보고된 바가 없다. 향후 전이성 췌장암의 뇌전이 양상에 대해 좀 더 많은 증례를 통한 연구가 필요하며, 췌장암의 빈번한 연수막전이 기전에 대해서도 추가 연구가 필요하다.

Keywords

References

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