A Case of Double Primary Cancer (Gallbladder cancer and pancreatic cancer) in Patient with Anomalous Union of Pancreaticobiliary Duct

  • Sung Yong Han (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Dong Uk Kim (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Geun Am Song (Department of Internal Medicine, Pusan National University College of Medicine)
  • Received : 2015.05.25
  • Accepted : 2015.06.22
  • Published : 2015.06.30

Abstract

Anomalous union of the pancreaticobiliary duct (AUPBD) has been shown to predispose to carcinomas of the biliary tract (bile duct and gallbladder) and pancreatic cancer because of chronic recurrent inflammatory reaction due to pancreatic or bile juice refluxes. However, pancreatic duct would be less affected by the bile because of the relatively higher intraductal pressure of the pancreatic duct. We report a case of metachronous pancreatic cancer in AUPBD patient without choledochal cyst who underwent cholecystectomy because of gallbladder cancer.

Keywords

References

  1. Kim YJ, Hyun JJ, Lee JM, Lee HS, Kim CD, Anomalous union of the pancreaticobiliary duct without choledochal cyst: is cholecystectomy alone sufficient?, Langenbecks Arch Surg 2014;399:1071-1076
  2. Yi SY, Gallbladder carcinoma associated with anomalous union of pancreatobiliary ductal system, Open Journal of Gastroenterology 2013;3:249-251
  3. Song HK, Kim MH, Myung SJ, et al. Choledochal Cyst Associated the with Anoma lous Union of Pancreaticobiliary Duct (AUP BD) Has a More Grave Clinical Course T han Choledochal Cyst Alone, Korean J Intern Med 1999;14(2)
  4. Funabiki T, Matsubara T, Miyakawa S, Ishihara S, Pancreaticobiliary maljunction and carcinogenesis to biliary and pancreatic malignancy Langenbecks Arch Surg 2009;394:159-169
  5. Hwang EJ, Dong SH, Congenital Pancreatobiliary Anomaly Associated with Pancreatobiliary Malignancy The Korean Society of Gastrointestinal Endoscopy 48th seminar
  6. Kimura K, Ohto M, Ono T, et al. Congenital cystic dilatation of the common bile duct: relationship to anomalous pancreaticobiliary ductal union. AJR Am J Roentgenol 1977;128(4):571-577.
  7. Kim SH, Kim HW, Kang DH, et al, A Case of Intrahepatic Cholangiocarcinoma Associated with Type IV Choledochal Cyst, Korean J Gastroenterol Vol. 60 No. 2, 123-127
  8. Nomura T, Shirai Y, Sandoh N, Nagakura S, Hatakeyama K. Cholangiographic criteria for anomalous union of the pancreatic and biliary ducts, Gastrointest Endosc 2002;55(2):204-8.
  9. Tsuchida A, Itoi T. Carcinogenesis and chemoprevention of biliary tract cancer in pancreaticobiliary maljunction, World J Gastrointest Oncol 2010;15(3):130-135