과립구집락자극인자 투여로 치료한 범혈구감소증과 피부 박리를 보인 붉은사슴뿔버섯 중독 1례

A Case of Podostroma Cornu-Damae Intoxication Induced Pancytopenia and Skin Desquamation: Successful Treatment with Granulocyte Colony Stimulation Factor (G-CFS)

  • Kim, Jung Seok (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Kim, Gyu Won (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Chung, Jae Il (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Sim, Myoung Ki (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Yoon, Ki Chul (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Choi, Yong Hoon (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Yi, Ha Ram (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Choi, In Zoo (Department of Internal Medicine, Sahmyook Seoul Hospital) ;
  • Shim, Chan Sup (Digestive Disease Center, Konkuk University Medical Center) ;
  • Han, Joung Ho (Department of Internal Medicine, Chungbuk National University College of Medicine)
  • 투고 : 2015.05.29
  • 심사 : 2015.06.07
  • 발행 : 2015.06.30

초록

Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. The morphology is similar to that of immature Ganoderma lucidum, making identification difficult for non-experts. We experienced such a case of a 56- year-old male who picked and consumed podostroma cornu-damae, and consumed. Later that day, he developed digestive system symptoms, including nausea, vomiting, and abdominal pain. He presented to the emergency room (ER), there were no abnormal physical findings, symptoms improved after gastric lavage, and the patient voluntarily discharged himself on the same day. The following day, as the symptoms gradually deteriorated, he was admitted via the ER. He was presented with severe pancytopenia, alopecia, desquamation of skin, and acute renal failure. He recovered without any complications after conservative care, antibiotics therapy, and granulocyte colony stimulating factor administration. The most commonly reported complications of podostroma cornu-damae intoxication were reported pancytopenia, infection, disseminated intravascular coagulation, acute renal failure, etc. since Prevention is especially important because its toxicity can be lethal and there is no particular treatment to date, prevention is especially important. Promotion and education for the public are needed.

키워드

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