KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Antioxidative and Anti-inflammatory Activities of Carrot flower

제주 당근 꽃의 항산화 및 항염증 활성

  • 김수경 ((재)제주테크노파크 바이오융합센터) ;
  • 변후돈 ((재)제주테크노파크 바이오융합센터) ;
  • 김상철 ((재)제주테크노파크 바이오융합센터) ;
  • 양경월 ((재)제주테크노파크 바이오융합센터) ;
  • 김정희 ((재)제주테크노파크 바이오융합센터) ;
  • 한종헌 ((재)제주테크노파크 바이오융합센터)
  • Received : 2014.04.07
  • Accepted : 2015.04.20
  • Published : 2015.04.27
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Abstract

The antioxidant and anti-inflammatory activities of extract and its fraction of Daucus carota var. sativa flower were studied in vitro. Extract and ethyl acetate fraction, butanol fraction of carrot flower showed radical scavenging effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH). We also investigated the effect of extract and ethyl acetate fraction, butanol fraction of carrot flower on NO production in a lipopolysaccharide (LPS)-stimulated murine macrophage RAW 264.7 cells. Extract and its fraction of carrot flower significantly inhibited NO production and this inhibitory action was not due to the cytotoxicity. This study suggests that extract and ethyl acetate fraction, butanol fraction of Daucus carota var. sativa flower could contribute to the chemoprevention and therapy of oxidative stress and inflammation.

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References

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