DOI QR코드

DOI QR Code

Tooth whitening maintenance efficacy of dentifrices containing several active ingredients in vitro and in vivo

유효성분들을 배합한 치약제의 실험실적 및 임상적 치아미백유지 효과

  • 안재현 ((주)LG생활건강 기술연구원) ;
  • 김지혜 ((주)LG생활건강 기술연구원) ;
  • 김종훈 ((주)LG생활건강 기술연구원)
  • Received : 2014.12.19
  • Accepted : 2015.04.06
  • Published : 2015.04.30

Abstract

Objectives: The purpose of this study was to investigate tooth whitening maintenance efficacy of several dentifrices containing effective ingredients for tooth whitening. Methods: Hydroxyapatite specimens(HAPs) staining was done by using modified Stookey's methods. HAPs were treated with 2.9% hydrogen peroxide containing strip for whitening, and were shaken with several dentifrice slurry(dentifrice 1 : artificial saliva 2) for 30 minutes. The HAPs were finally dipped in staining solution for an hour. Shaking and dipping were repeated 4 times and lightness values were measured by colorimeter at each step. In clinical test, test 4 dentifrice and control dentifrice were evaluated by 21 subjects for 2 months after receiving institutional review board(IRB) approval. Organoleptic(vita shade guide) and instrumental(SHADEEYE-NCC) evaluation were performed for whiteness change of teeth. Statistical analysis was performed using repeated measures ANOVA, Tukey's post hoc test and ${\chi}^2$-test(p<0.05). Results: All dentifrices showed statistical significance in comparison with control dentifrice containing sodium fluoride and test 4 dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax, and sodium fluoride showed statistical significance in comparison with other dentifrices by inhibiting staining in vitro(p<0.05). In clinical test, test 4 dentifrice showed better effects than control dentifrice in organoleptic and instrumental evaluation in tooth whitening maintenance efficacy(p<0.05). The awareness toward tooth whitening maintenance efficacy for 2 months use showed that test 4 dentifrice was much better than control dentifrice, but did not show statistically significant(p>0.05). Conclusions: Dentifrice containing sodium pyrophosphate, sodium metaphosphate, candelilla wax and sodium fluoride was more effective in keeping teeth white.

Keywords

References

  1. Heymann HO. Tooth whitening: facts and fallacies. Br Dent J 2005; 198(8): 514. https://doi.org/10.1038/sj.bdj.4812298
  2. Yang HY, Kim EK, Choi SS, Cho MJ, Lee YE, Yoon HY, et al. Clinical evaluation of bleaching effect of 3% hydrogen peroxide strip with primer on human enamel. J Korean Soc Dent Hyg 2014; 13(5): 901-8. http://dx.doi.org/10.13065/jksdh.2013.13.05.901.
  3. Oral care in the United States. Euromonitor International July 2013; Passport 4.
  4. Ministry of Food and Drug Safety. Rule book of quasi-drug. Cheongju: Ministry of Food and Drug Safety; 2014: 305-9.
  5. Joiner A, Thakker G. In vitro evaluation of a novel 6% hydrogen peroxide tooth whitening product. J Dent 2004; 32(1): 19-25. https://doi.org/10.1016/j.jdent.2003.10.007
  6. Leonard RH, Sharma A, Haywood VB. Use of different concentration of carbamide peroxide for bleaching teeth: an in vitro study. Quintessence Int 1998; 29: 503-7.
  7. Haywood VB, Houck VM, Heymann HO. Nightguard vital bleaching: effect of various solution on enamel surface texture and color. Quintessence Int 1991; 22: 775-82.
  8. Farrell S. Placebo-controlled trial evaluating safety with 12-months continuous use of 6% hydrogen peroxide whitening strips. J Dent 2008; 36: 726-30. https://doi.org/10.1016/j.jdent.2008.05.004
  9. Shahidi H, Barker ML, Sagel PA, Gerlach RW. Randomized controlled trial of 10% hydrogen peroxide whitening strips. J Clin Dent 2005; 16: 91-5.
  10. Ahn JH, Kim JH, Kim JH, Jang JW, Oh YJ, Park YD. Tooth whitening effect of toothpaste containing hydrogen peroxide. J Korean Soc Dent Hyg 2014; 14(1): 101-8. http://dx.doi.org/10.13065/jksdh.2014.14.01.101.
  11. Cho MJ, Lee ES, Park JR, Jeong JY, Keon SB, Han KS, et al. Dental prophylaxis. 5th ed. Seoul: Komoonsa; 2012: 24-7.
  12. Nam SH, Choi JO. Efficacy and evaluation of tooth stain with various pH beverages following whitening dentifrice. J Dent Hyg Sci 2013; 13(2): 191-6.
  13. Kim EH, Lee DH, Oh HS. Effect of the repetitive tasting of different blending types of coffee on teeth stain during home bleaching. J Korean Soc Dent Hyg 2010; 10(6): 955-63.
  14. Jung SH, Park DY, Ma DS. Efficacy of six month of a 2.6% hydrogen peroxide containing tooth-whitening strips. J Korean Acad Dent Health 2004; 28(1): 117-25.
  15. Kim YS, Kwon HK, Kim BI. Effect of nano-carbonate apatite to prevent re-stain after dental bleaching in vitro. J Dent 2011; 39: 636-42. https://doi.org/10.1016/j.jdent.2011.07.002
  16. Bahng KH, Yoo SM, Park YD. Maintenance of teeth brightness with 0.3% $H_2O_2$ containing toothpaste after use of 3.0% $H_2O_2$ brightening gel. J Korean Acad Dent Health 2007; 31(2): 167-75.
  17. Stookey GK, Burhard TA, Schemehorn BR. In vitro removal of stain with dentifrices. J Dent Res 1982; 11: 1236-9.
  18. Kim JB, Paik DI, Moon HS, Ma DS. A clinical comparison of the anticalculus effect of two kinds of therapeutic dentifrice. J Korean Acad Dent Health 1989; 13(1): 7-16.
  19. Ma DS, Park DY, Park DI, Moon HS, Kim JB. A clinical study of toothpaste containing pyrophosphate, hydroxyapatite and Vitamin-E on the prevention of calculus formation and gingivitis. J Korean Acad Dent Health 1998; 22(1): 13-8.
  20. Ayad F, De Sciscio P, Stewart B, De Vizio W, Petrone ME, Volpe AR. The stain prevention efficacy of two tooth whitening dentifrices. Compend Contin Educ Dent 2002; 23(8): 733-6.
  21. Jung SH, Bae KH, Lee WJ, Moon HS, Paik DI, Kim JB. Clinical study on the effect of therapeutic toothpaste containing tetrasodium pyrophosphate, vitamin E and hydrogen peroxide on the tooth whitening. J Korean Acad Dent Health 2001; 25(2): 221-6.
  22. Cavalli V, Arrais CAG, Giannin M, Ambrosano GMB. High-concentrated carbamide peroxide bleaching agents effects on enamel surface. J Oral Rehabil 2004; 31(2): 155-9. https://doi.org/10.1111/j.1365-2842.2004.01138.x
  23. Kang SM, Kim HE, Kwon HK, Kim BI. Inhibition of post-bleach stain by dentifrice containing nano-carbonate apatite. J Korean Acad Dent Health 2008; 32(1): 42-53.

Cited by

  1. The Tooth Whitening Effect of Toothpaste Containing High Cleaning Silica and Sodium Hexametaphosphate and the Preventive Effect of Staining by Coffee, Tea and Wine vol.16, pp.4, 2015, https://doi.org/10.15236/ijcpd.2020.16.4.192