Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Prevalence of Detection of Prohibited Drugs on Doping Tests of Pre- and Post-races in Korea (2002-2013)

국내 경주마 도핑검사에서 금지약물 검출빈도 및 종류(2002-2013)

  • Yang, Jaehyuk (Department of equine industry, Korea National College of Agriculture and Fisheries) ;
  • Han, Kwan-Seok (Korea Racing Authority) ;
  • Yang, Young-Jin (Korea Racing Authority) ;
  • Lim, Yoon-Kyu (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 양재혁 (국립 한국농수산대학 말산업학과) ;
  • 한관석 (한국마사회) ;
  • 양영진 (한국마사회) ;
  • 임윤규 (제주대학교 수의과대학 및 수의과학연구소)
  • Accepted : 2015.02.14
  • Published : 2015.04.30
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Abstract

There was no study on the prevalence of doping control of racehorses in Korea. The purpose of this study was to determine prohibited substances in horse races of a drugs testing program. Blood samples were taken from those 298,543 starters prior to racing and the that finished top 3 runners of each race and horses designated by the stewards shall be taken for collection of 91,482 urine samples for the purpose of post-race doping test in Seoul, Busan and Jeju Race Park between 2002 and 2013. Detection and measurement of prohibited substances were carried out by ELISA, GC/MS and LC/MS using standard methods at the Doping Control Center, Korea Racing Authority. Total 0.0030% of pre-races and total 0.0186% of post-races tested positive for prohibited substances. In pre- and post-race, caffeine and ketoprofen were the most detected prohibited substance respectively. We thought that characteristics of pharmacokinetics and pharmacodynamics of drugs resulted in different between plasma and urine. These substances have also been detected with other prohibited drugs suggesting that unintentional feeding or bedding may be the reason and groomers' confusion of candidate horses based by the stewards' research.

국내경주마에서 검출되는 금지약물의 종류와 빈도는 보고된 바 없다. 본 연구의 목적은 국내 경마장에서 검출되는 금지약물의 종류와 검출빈도를 알아 보고자 2002년부터 2013년까지 국내 3개의 경마장에서 29,543 마리의 경주 전 경주마에서 채혈하였고, 경주 후에 3위 이내의 경주마와 재결지정마 91,482 마리에서 채뇨하여 효소면역분석법, 가스 크로마토그래프 질량분석계 그리고 액체 크로마토그래프 질량분석계를 이용하여 한국마사회 도핑검사소에서 검사하였다. 기간 중 경주전후 도핑 양성률은 각각 0.0030%, 0.0186%였으며, 경주 전에는 caffeine 그리고 경주 후에는 ketoprofen이 가장 많이 검출되었다. 약물의 약물동력적 및 약력학적 특성 때문에 혈액과 뇨의 결과가 달랐다고 생각된다. 그리고 재결위원의 조사결과, 금지약물검출은 오염된 사료 또는 깔짚에서 말에게 옮겨졌거나 출주예정마에 대한 말관리사의 혼란에서 비롯되었다.

Keywords

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