Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Evaluation of Left Ventricular Tei Index in the Normal Dogs and Dogs with Mitral Valve Degenerative Disease

정상 및 퇴행성이첨판 질환이 있는 개에서 조직도플러를 통한 좌심실 Tei index의 평가

  • Lee, In (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lee, Jung-Woo (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Choi, Soo-Young (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Han, Woo-Sok (College of Medicine, Konyang University) ;
  • Lee, Ki-Ja (College of Veterinary Medicine, Kyungpook National University) ;
  • Lee, Young-Won (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Choi, Ho-Jung (College of Veterinary Medicine.Research Institute of Veterinary Medicine, Chungnam National University)
  • 이인 (충남대학교 수의과대학.동물의과학 연구소) ;
  • 이정우 (충남대학교 수의과대학.동물의과학 연구소) ;
  • 최수영 (충남대학교 수의과대학.동물의과학 연구소) ;
  • 한우석 (건양대학교 의과대학) ;
  • 이기자 (경북대학교 수의과대학) ;
  • 이영원 (충남대학교 수의과대학.동물의과학 연구소) ;
  • 최호정 (충남대학교 수의과대학.동물의과학 연구소)
  • Accepted : 2015.04.10
  • Published : 2015.04.30
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Abstract

Tei-index has been reported as one of reliable echocardiographic factors for evaluating cardiac function in human and small animals. In this study, Tei-index were measured and evaluated with other echocardiographic parameters in normal thirteen beagle dogs and thirty-one dogs with mitral valve degeneration. Normal range of Tei index with tissue Doppler obtained at septum and left ventricular free wall was $0.58{\pm}0.07$ and $0.60{\pm}0.07$, respectively. The values between septum and left ventricular free wall did not show significant difference. Tissue Doppler derived tei index showed better reproducibility and significantly lower values than the results obtained by pulsed wave Doppler. Tei index obtained in either method increased with the progression of clinical signs. Therefore, the increase of Tei index in dogs with mitral regurgitation is thought to be an useful factor reflecting left ventricular dysfunction.

좌심실의 용적과부하와 심할 경우 심근 기능부전을 일으키는 질병에서 Tei index는 심근기능을 평가하는데 있어 비교적 측정이 쉽고 재현율이 양호하다고 보고된 심초음파 측정 요소이다. 본 연구에서는 정상 및 퇴행성 이첨판 질환이 있는 개에서 조직도플러와 펄스파 도플러를 통해 Tei index 값을 측정하고, 다른 초음파평가지표와 비교평가하였다. 정상 개에서 Tei index 측정을 위해 심혈관계에 이상이 없는 13마리의 비글견을 사용하였으며, 이첨판 역류를 진단받은 환자 31마리를 환자군으로 하여 각각의 환자는 임상증상에 따라 세 개의 그룹으로 나뉘어 각 측정치를 비교하였다. 본 실험 결과에서 대부분의 측정항목들이 좋은 신뢰도를 보였으며, Tei index의 경우 조직도플러를 통한 Tei index가 펄스파 도플러에 비해 좀 더 높은 신뢰도를 나타내었다. 본 실험에서 정상 개에서 Tei index는 조직도 플러의 심실외벽과 중격에서 각각 $0.58{\pm}0.07$, $0.60{\pm}0.07$로 측정되었다. 조직도플러 검사 결과 중격과 좌심실벽 지점간에는 Tei index의 차이가 나타나지 않았다. 펄스파도플러를 통해 측정한 Tei index는 조직도플러를 통해 측정한 Tei index에 비해 유의성 있게 낮게 측정되었다. 정상 및 퇴행성이첨판 질환이 있는 환자군에서 Tei index는 두 가지 측정 방식 모두에서 이첨판 역류의 임상증상에 따라 그룹별로 유의적으로 증가하는 것으로 나타났다. 따라서, Teiindex는 이첨판 역류가 있는 개에서 좌심실 기능 저하를 반영하는 유용한 검사 요소로 생각된다.

Keywords

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