Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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A Case of Childhood Typhoid Fever Complicated with Acute Nephritis

소아 장티푸스에서 병발된 사구체 신염

  • Oh, Eun Min (Department of Pediatrics, Korea University College of Medicine) ;
  • Sim, Ji Hyun (Department of Pediatrics, Korea University College of Medicine) ;
  • Hwang, Ji Hyen (Department of Pediatrics, Korea University College of Medicine) ;
  • Yim, Hyung Eun (Department of Pediatrics, Korea University College of Medicine) ;
  • Kim, Yun-Kyung (Department of Pediatrics, Korea University College of Medicine)
  • 오은민 (고려대학교 의과대학 소아과학교실) ;
  • 심지현 (고려대학교 의과대학 소아과학교실) ;
  • 황지현 (고려대학교 의과대학 소아과학교실) ;
  • 임형은 (고려대학교 의과대학 소아과학교실) ;
  • 김윤경 (고려대학교 의과대학 소아과학교실)
  • Received : 2014.08.27
  • Accepted : 2014.10.26
  • Published : 2015.04.25
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Abstract

Typhoid fever can cause serious complications, such as enterobrosia, meningitis, pneumonia, myocarditis, hepatitis, osteomyelitis, and disseminated intravascular coagulation in 10-15% of the patients. Kidney complications are very rare, and a few cases have been reported in children. We are reporting a case of childhood typhoid fever complicated with acute nephritis present with albuminuria, hypertension, and renal failure.

장티푸스는 10-15%에서 수막염, 폐렴, 심근염, 간염, 골수염, 파종성 혈관내 응고병증등의 심각한 합병증을 유발할수 있다. 소아에서 장티푸스 병발 후 신장에 발생되는 합병증은 국내외 모두 매우 드물다. 우리는 장티푸스 병발후 단백뇨, 고혈압, 신기능 저하가 동반된 급성 사구체 신염 케이스를 경험후 보고하는 바이다. 이 케이스는 대변 배양검사에서 병원체를 확인할 수는 없었지만 상승하는 Widal 수치로 장티푸스를 진단할 수 있었다. 장티푸스는 유병률은 감소하였지만 고열이 있는 경우 여전히 고려해보아야 하는 중요한 질환이다.

Keywords

References

  1. Lee JK. Summary of communicable disease outbreak during thirty fifth week in 2007. Communicable disease weekly report 2007;6:1-35.
  2. Zulfigar AB, Enteric fever. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE, eds. Nelson Textbook of Pediatrics. 19th ed, Philadelphia: WB Sounders Co, 2011:955.
  3. Qutaishat SS, Stemper ME, Spencer SK, Borchardt MA, Opitz JC, Monson TA, et al. Transmission of Salmonella enterica serotype typhimurium DT 104 to infants through mother's breast milk. Pediatrics 2003;6:1442-6.
  4. Park JK, Seok WW, Choi BJ, Kim HM, Lim BK, Yoon SS, et al. Salmonella enterica serovar London infections associated with consumption of infant formula. Yonsei Med J 2004;45:43-8. https://doi.org/10.3349/ymj.2004.45.1.43
  5. Lim HS. Contributing factors of infectious waterborne and foodborne outbreaks in Korea. J Korean Med Assoc 2007;50:582-91. https://doi.org/10.5124/jkma.2007.50.7.582
  6. Lim HS, Min YS, Lee K, Lim SH. Epidemiologic investigation into an outbreak of typhoid fever recognized by electronic data interchange in gyeongsanbuk-do, 2003. Korean J Epidemiol 2004; 26:59-68.
  7. Shin SY, Hong JY, Bae JM. An Epidemic survey for salmonellosis occurred on a baby's first birthday banquet in Jeju Island. Korean J Epidemiol 2004;26:27-38.
  8. Parry CM, Hien TT, Dougan G, White NJ, Farrar JJ. Typhoid fever. N Engl J Med 2002;347:1770-82. https://doi.org/10.1056/NEJMra020201
  9. Janssen van Doorn K, Pierard D, Verbeelen D. Typhoid fever. N Engl J Med 2003;20:1182-4.
  10. Hayashi M, Kouzu H, Nishihara M, Takahashi T, Furuhashi M, Sakamoto K, et al. Acute renal failure likely due to acute nephritis syndrome associated with typhoid fever. Intern Med 2005;44:1074-7. https://doi.org/10.2169/internalmedicine.44.1074
  11. Sreedharan R, Avnar ED, Acute renal failure. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE, eds. Nelson Textbook of Pediatrics. 19th ed, Philadelphia: WB Sounders Co, 2011:1818.
  12. Sitprija V, Pipatanagul V, Boonpucknavig V, Boonpucknavig S. Glomerulitis in typhoid fever, Ann Intern Med 1974;81:210-3. https://doi.org/10.7326/0003-4819-81-2-210
  13. Oh JM, Lee NR, Yim HE, Yoo KH, Jeong WY, Hong YS, et al. Acute tubulointerstitial nephritis with renal failure complicated by typhoid fever, J Korean Soc Pediatr Nephrol 2010;14:236-9. https://doi.org/10.3339/jkspn.2010.14.2.236
  14. Buysen JG, Houthoff HJ, Krediet RT, Arisz L. Acute interstitial nephritis: a clinical and morphological study in 27 patients. Nephrol Dial Transplant 1990;5:94-9. https://doi.org/10.1093/ndt/5.2.94
  15. Shin PJ, Lee HS, Cho BS, Ahn CI, Yang MH. Acute tubular necrosis associated with typhoid fever, Korean J Pediatr 1994;37:250-6.
  16. Murithi AK, Leung N, Valeri AM, Cornell LD, Sethi S, Fidler ME et al. Biopsy-proven acute interstitial nephritis, 1993-2011: A case series, Am J Kidney Dis 2014;64:558-66. https://doi.org/10.1053/j.ajkd.2014.04.027