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Limited immune tolerance induced by transient mixed chimerism

  • Yu, Ji Hyun (Division of Nephrology, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Chung, Byung Ha (Division of Nephrology, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Oh, Eun Ji (Department of Laboratory Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Kim, Ji-Il (Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Kim, Hee-Je (Department of Hematology, Catholic Blood and Marrow Transplantation Center, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Moon, In Sung (Department of Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Yang, Chul Woo (Division of Nephrology, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea)
  • Received : 2014.10.25
  • Accepted : 2014.11.27
  • Published : 2015.09.01

Abstract

Keywords

Acknowledgement

Supported by : Ministry for Health and Welfare

References

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  3. Sellares J, de Freitas DG, Mengel M, et al. Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence. Am J Transplant 2012;12:388-399. https://doi.org/10.1111/j.1600-6143.2011.03840.x
  4. Leventhal J, Abecassis M, Miller J, et al. Tolerance induction in HLA disparate living donor kidney transplantation by donor stem cell infusion: durable chimerism predicts outcome. Transplantation 2013;95:169-176. https://doi.org/10.1097/TP.0b013e3182782fc1
  5. Kawai T, Sachs DH, Sprangers B, et al. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant 2014;14:1599-1611. https://doi.org/10.1111/ajt.12731