Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Dietary Supplementation of Mushroom Water Suppresses Fat Accumulation in High Fat Diet Induced-Obese Female Mice and Enhances Immune Cell Development in Non-Obese Mice

  • Bing, So Jin (Department of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Ho, Manh Tin (Department of Biochemistry School of Medicine, Jeju National University) ;
  • Sophors, Phorl (Department of Biochemistry School of Medicine, Jeju National University) ;
  • Park, Sanggyu (Division of Life & Environmental Science, Daegu University) ;
  • Yun, Young Min (Department of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jee, Youngheun (Department of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Cho, Moonjae (Department of Biochemistry, School of Medicine, Institute of Medical Science, Jeju National University)
  • Received : 2014.12.22
  • Accepted : 2015.01.14
  • Published : 2015.03.31
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Abstract

Extracted mushroom water showed an ability to suppress the accumulation of body fat in female mice after feeding 5 weeks with high fat diet. Particularly, in parametrial and mesenteric adipose, it significantly reduced 44 and 47% of weight, respectively. In non-obese mice, maturated NK cell ($CD11b^{hi}CD27^{lo}$) population were increased ($70.9{\pm}3.8%$) in mushroom water fed mice compared to control ($61.4{\pm}4.3%$) and NK cell population were augmented in mushroom fed mice compared to control.

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References

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