Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Low Grade Pulmonary Lymphomatoid Granulomatosis with an Endobronchial Mass

  • Kim, Kyung Hoon (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Park, Jinhee (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Yoo, Ji Yeon (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kim, Min Jae (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kim, Il (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Rhee, Chin Kook (Division of Pulmonary Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Lee, Hea Yon (Division of Pulmonary Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
  • Received : 2014.09.18
  • Accepted : 2014.12.10
  • Published : 2015.02.28
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Abstract

Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive neoplastic proliferation of B and T lymphocytes commonly involving the lungs. Epstein-Barr virus is commonly detected in lesional cells. We report a case of a 54-year-old female with underlying monoclonal gammopathy of unknown significance who presented with a 4 week history of dyspnea and cough. Computed tomography scan of the chest showed multiple lung nodules as well as endobronchial narrowing causing atelectasis at the left upper lobe. Bronchoscopic findings revealed obstruction at the lingula segment due to endobronchial mass as a rare presentation. Bronchoscopic biopsy was diagnosed with LYG grade 1. After treatment, the endobronchial mass and lung lesions were completely resolved. However, the patient eventually evolved to malignant lymphoma after 1 year.

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References

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