참고문헌
- Eizirik DL, Colli ML and Ortis F (2009) The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 5, 219-226 https://doi.org/10.1038/nrendo.2009.21
- Holohan C, Szegezdi E, Ritter T, O'Brien T and Samali A (2008) Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL. J Cell Mol Med 12, 591-606 https://doi.org/10.1111/j.1582-4934.2007.00191.x
- Rabinovitch A and Suarez-Pinzon WL (1998) Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus. Biochem Pharmacol 55, 1139-1149 https://doi.org/10.1016/S0006-2952(97)00492-9
- Southern C, Schulster D and Green IC (1990) Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett 276, 42-44 https://doi.org/10.1016/0014-5793(90)80502-A
- Chen MC, Proost P, Gysemans C, Mathieu C and Eizirik DL (2001) Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells. Diabetologia 44, 325-332 https://doi.org/10.1007/s001250051622
- Sarkar SA, Lee CE, Victorino F et al (2012) Expression and regulation of chemokines in murine and human type 1 diabetes. Diabetes 61, 436-446 https://doi.org/10.2337/db11-0853
- Eizirik DL and Mandrup-Poulsen T (2001) A choice of death-- the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 44, 2115-2133 https://doi.org/10.1007/s001250100021
- Karin M and Delhase M (2000) The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signaling. Semin Immunol 12, 85-98 https://doi.org/10.1006/smim.2000.0210
- Allison AC, Cacabelos R, Lombardi VR, Alvarez XA and Vigo C (2001) Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry 25, 1341-1357 https://doi.org/10.1016/S0278-5846(01)00192-0
- Kannaiyan R, Shanmugam MK and Sethi G (2011) Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer. Cancer Lett 303, 9-20 https://doi.org/10.1016/j.canlet.2010.10.025
- Grant CW, Moran-Paul CM, Duclos SK, Guberski DL, Arreaza-Rubín G and Spain LM (2013) Testing Agents for Prevention or Reversal of Type 1 Diabetes in Rodents. PLoS One 8, e72989 https://doi.org/10.1371/journal.pone.0072989
- Kim JE, Lee MH, Nam DH et al (2013) Celastrol, an NF-κB inhibitor, improves insulin resistance and attenuates renal injury in db/db mice. PLoS One 8, e62068 https://doi.org/10.1371/journal.pone.0062068
- Corbett JA and McDaniel ML (1992) Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM. Diabetes 41, 897-903 https://doi.org/10.2337/diab.41.8.897
- Igoillo-Esteve M, Marselli L, Cunha DA et al (2010) Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. Diabetologia 53, 1395-1405 https://doi.org/10.1007/s00125-010-1707-y
- Cardozo AK, Heimberg H, Heremans Y et al (2001) A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells. J Biol Chem 276, 48879-48886 https://doi.org/10.1074/jbc.M108658200
- Pirot P, Cardozo AK and Eizirik DL (2008) Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes. Arq Bras Endocrinol Metabol 52, 156-165 https://doi.org/10.1590/S0004-27302008000200003
- Cameron MJ, Arreaza GA, Grattan M et al (2000) Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes. J Immunol 165, 1102-1110 https://doi.org/10.4049/jimmunol.165.2.1102
- Zhao Y, Krishnamurthy B, Mollah ZU, Kay TW and Thomas HE (2011) NF-κB in type 1 diabetes. Inflamm Allergy Drug Targets 10, 208-217 https://doi.org/10.2174/187152811795564046
- Häcker H and Karin M (2006). Regulation and function of IKK and IKKrelated kinases. Sci STKE 2006, re13 https://doi.org/10.1126/stke.3572006re13
- Lee JH, Koo TH, Yoon H et al (2006) Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. Biochem Pharmacol 72, 1311-1321 https://doi.org/10.1016/j.bcp.2006.08.014
- Kwon DJ, Bae YS, Ju SM, Youn GS, Choi SY and Park J (2014) Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages. BMB Rep 47, 318-323 https://doi.org/10.5483/BMBRep.2014.47.6.200
- Youn GS, Kwon DJ, Ju SM, Choi SY and Park J (2013) Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells. BMB Rep 46, 410-415 https://doi.org/10.5483/BMBRep.2013.46.8.014
- Park MC, Kim D, Lee Y and Kwon HJ (2013) CD83 expression induced by CpG-DNA stimulation in a macrophage cell line RAW 264.7. BMB Rep 46, 448-453 https://doi.org/10.5483/BMBRep.2013.46.9.023
- Shin SY, Kim CG and Lee YH (2013) Egr-1 regulates the transcription of the BRCA1 gene by etoposide. BMB Rep 46, 92-96 https://doi.org/10.5483/BMBRep.2013.46.2.202
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