Imaging Science in Dentistry

Korean Academy of Oral and Maxillofacial Radiology (대한영상치의학회)
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Volumetric quantification of bone-implant contact using micro-computed tomography analysis based on region-based segmentation

  • Kang, Sung-Won (Interdisciplinary Program in Radiation, Applied Life Science Major, College of Medicine, BK21, and Dental Research Institute, Seoul National University) ;
  • Lee, Woo-Jin (Interdisciplinary Program in Radiation, Applied Life Science Major, College of Medicine, BK21, and Dental Research Institute, Seoul National University) ;
  • Choi, Soon-Chul (Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Lee, Sam-Sun (Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Heo, Min-Suk (Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Huh, Kyung-Hoe (Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Kim, Tae-Il (Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University) ;
  • Yi, Won-Jin (Department of Oral and Maxillofacial Radiology, BK21, and Dental Research Institute, School of Dentistry, Seoul National University)
  • Received : 2014.07.10
  • Accepted : 2014.11.17
  • Published : 2015.03.31
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Abstract

Purpose: We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA). Materials and Methods: The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method. Results: VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05). Conclusion: It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.

Keywords

References

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